“a strong trend”

Moreover, a strong trend was demonstrated for decreased LDL cholesterol (100 ± 8 mg/dL (2.59 ± 0.21) to 93 ± 7 (2.40 ± 0.18); p = 0.05) and a decline in TC:HDL ratio from 4.0 ± 0.3 during control to 3.7 ± 0.2 during the fiber intervention ( p = 0.02) period.

We also detected decreased expression (a strong trend p=0.05) of ghrelin receptor-1a (GHSR), the central target of the appetite hormone ghrelin ( 38 ).

6 A meta-analysis of 18 studies involving 146,372 octogenarians reported a strong trend toward reduced mortality in OPCAB patients (odds ratio, 0.75; 95% CI, 0.56-1.00; P = .05), although statistical significance was not reached. 4 The ability of OPCAB to dampen systemic inflammatory responses, to minimize organ dysfunction, and to reduce physiologic stress may account for its lower 30-day mortality rate. 7 Although OPCAB patients received fewer grafts overall, their ICOR was significantly higher compared with ONCAB patients.

In the subgroup of lung cancer patients, we observed the following differences that were significant or showed a strong trend when compared to baseline: sFLT (at RTduring, p = 0.05), PlGF (at RTduring and RTend, p = 0.01), VEGF-C (at RTduring and RTend, p < 0.001; at FU1, p = 0.04), VEGF-D (FU1, p < 0.001), INF-γ (FU1, p = 0.008), IL-8 (at RTend, p = 0.02; at FU1, p = 0.03; and at FU2, p = 0.03) and HGF (at FU1, p = 0.01).

There was no main effect of CNO on chow intake in female rats, although there was a strong trend ( P = 0.05) for CNO to reduce peanut butter intake in females at the 1 h timepoint [CNO x sex, F(1, 13) = 9.426, P = 0.008; CNO F(1, 13) = 0.3, P = 0.5903; sex F(1,13) = 0.06728, P = 0.8].

We also found a strong trend (two-tailed permutation test without FDR correction; P <0.05) towards a greater association of genes with phenotypes related to lethality, including premature death and complete embryonic lethality, in the permutation set as compared to the avian missing gene set (Additional file 1 : Table S10B).

A higher mean dose to the heart base showed a strong trend toward reduced survival (HR, 3.70; P = .05).

There was a strong trend for NT-proBNP levels at discharge to independently predict 30-day mortality ( P = 0.05).

For the variant counts (B), there was a significant reduction in the long ccfDNA fraction compared to the medium ccfDNA fraction and a strong trend to have fewer counts than the short ccfDNA fraction. *P<0.05, **P<0.01, ***P<0.001.

The group effect in right anterior insula remained significant or showed a strong trend when controlling for either psychopathic traits ( p = .05, svc) or CU traits ( p < .05, svc).

8 mg/kg FA fortification prevented the occurrence of radiation-induced defects in the cervical region, whilst the 12 mg/kg diet group also showed a strong trend (henceforth defined as P = 0.05–0.08) toward prevention ( Figure 4 , cervical vertebrae).

5b ), a strong trend for a significant difference in EAE clinical score could be detected 11 (xCT +/+ vs. xCT −/− BM mice: 0.75 ± 0.23 vs. 0.21 ± 0.12; p = 0.050; n = 13–14) and 14 days (xCT +/+ vs. xCT −/− BM mice: 3.31 ± 0.26 vs. 2.46 ± 0.21; p = 0.054; n = 13–14) after immunization, with a better outcome for mice lacking xCT in their immune cells (Fig. 5a ).

As shown in Fig 6 , simvastatin induced a significant decrease in -HAD activity in the EDL Sim 60 and Sim 80 groups ( Fig 6C ), with a strong trend (p = 0.05, main effect) for a decrease in the PLT Sim 60 and Sim 80 groups ( Fig 6B ).

There was a strong trend of reduced relative CSA and reduced lesion CSA of fdESC treated tendons compared to that of CONT tendons (one-tailed P = 0.05 and P = 0.06, respectively; Table 1 ).

However, a strong trend of improved survival was reported among patients with AA who underwent radical surgery, as opposed to local surgical therapies (HR, 0.71; 95% CI, 0.51–1.00; P = 0.05)[ 6 ].

RV LAS only revealed an association with total EAT volume during exercise stress, while impaired right atrial (RA) LAS was associated with higher total EAT volume at rest ( P < 0.001) and showed a strong trend for an association during exercise stress ( P = 0.050) (cf.

Compared with patients without DSA, engraftment rate of patients receiving buffy coat was comparable (SHR, 0.89; 95% CI, 0.53-1.50; P = .661), whereas there was a strong trend toward a reduced rate of engraftment in DSA patients who received desensitization without buffy infusion (SHR, 0.46; 95% CI, 0.21-1.00; P = .050) ( Figure 3A ).

Specifically, between‐group differences for PEF%p, PEF, FVC, FEV1%p, and FEV1 for the change from baseline to week 52 were statistically significant and between‐group differences for FVC%p reached a strong trend ( P < 0.05 at weeks 13, 26, and 39; P = 0.082 at week 52). 17 Overall, the results of the study indicate a consistent slowing of the decline of these pulmonary function outcomes.

A strong trend in difference between phenotypes was observed for component 6, but did not reach statistical significance (F(2,84) = 2.98, p = 0.05) (Supplemental Table S3).

Significant effects were also observed for CSF p-tau (OR = 1.8, 95% C.I.: [1.14–2.7], p = 0.01) and CSF t-tau (OR = 1.6, 95% C.I.: [1.06–2.5], p = 0.03) while hippocampal volume displayed a strong trend (OR = 1.5, 95% C.I.: [1.00–2.29], p = 0.05).

In the insoluble fraction, APP/PS1 mice show an increased concentration of Aβ 1–42 ( W = 16, p = .03) compared with their control mice, whereas for 3xTg there was a strong trend toward an increase ( W = 63, p = .05) compared with their controls (Figure 2B ).

Free-viewing test Compared with HCs, CHR group exhibited a strong trend of reduced average saccade amplitude ( F = 3.926, p = 0.050, η 2 p = 0.040), significantly shortened scan path length ( F = 7.423, p = 0.008, η 2 p = 0.072) and increased average fixation duration ( F = 5.667, p = 0.019, η 2 p = 0.057) ( Table 2 ).

There was a strong trend toward worse OS for high FGFR1 amplification compare to low/no FGFR1 amplification group in multivariate analysis (HR 1.53; 95% CI, 0.99-2.34, P =0.050).

This overall positive versus negative comparison revealed a strong trend with a relative higher prevalence of ‘all TMD” in the abnormal group ( p = 0.05) ( Table 3 ).

[ 6 ], assessing the movement of the BN and base during voluntary MPFC and VM in 60 asymptomatic and 60 incontinent women, found a strong trend for the continent women to have greater BN elevation (p<0.05).