In this study, relative to Nx-Veh, SuHx-Veh had significantly increased expression of E-selectin, Sele [ p = 0.0003] ( Figure 6A ), vascular cell adhesion molecule-, Vcam-1 [ p = 0.0102] ( Figure 6C ), connective tissue growth factor, Ctgf [ p < 0.05] ( Figure 6D ), and osteopontin, Spp1 [ p = 0.0025] ( Figure 6E ), with a strong trend for elevated P-selectin, Slep [ p = 0.0939] ( Figure 6B ).
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Furthermore, in the GSE21501 cohort, including 102 PDAC patients, we observed a strong trend towards shorter OS (log Rank P <0.094) for HMGA2-high patients, which remained in the Cox Proportional Hazards model (HR 1.50 (0.92–2.45 95% confidence interval); P <0.103) ( Figure 2B ).
In our univariate analysis, a positive PSMA-PET scan showed a strong trend toward being a predictor for worse LC (HR = 6.94, p=0.095), though it was not statistically significant, again likely due to low event rates.
There was a strong trend for more frequent FITC extravasation observed in WT mice compared to KO mice (Fischer's Exact two tailed test P < 0.095).
The differences in circulating CD4+ (or CD8+) T lymphocyte counts between animals treated 14 days pi and placebo-treated animals did not reach significance, but a strong trend was observed in relation to the CD4+ T cell count (p = 0.095).
A strong trend was found at electrode 6 (around AFz) between the unpleasant and pleasant condition with p = 0.095 (t(18) = 1.760) as well as at electrode 8 (around FPz) between the neutral and unpleasant condition with p = 0.098 (t(18) = −1.747).
Evaluation of multivariate analysis when stratifying by histologic subtype revealed that among KSCC patients, the CCI score appeared to be associated with worse OS, with patients with a CCI score of 1 displaying a strong trend to worse OS (HR: 1.253; 95% CI: 0.962–1.633; P = 0.095), and those with a CCI score of 2 displaying a statistically significant association with worse OS (HR: 1.848; 95% CI: 1.199–2.849; P = 0.005) when compared to patients without comorbidity.
A significant increase was observed in hippocampal Ccl21a expression ( p = 0.02, Mann–Whitney test) in Figure 4 in the old mice compared to the young mice, as well as a strong trend for increased expression in the prefrontal cortex ( p = 0.095, Mann–Whitney test).
Finally, patients with pre-existing COPD had significantly lower BMD values ( Figure 2 F) and patients with pre-existing malignant disease showed a strong trend towards lower BMD values ( p = 0.096, Figure 2 G).
Compared to the controls, a significant ( p < 0.05) height loss was found with damaged IVDs under dynamic loading, and a strong trend in height loss ( p = 0.097) was seen with damaged IVDs under static loading ( Figure 3 b).
There was a strong trend towards a correlation between the half-life of resting CD4 T cell SIV DNA and viral load using the KVA10 escape data using a two-tailed test (r = −0.4138, p = 0.0971).
Although the number of sarcomatoid tumors in this cohort was low, a strong trend for increased JAK2 protein levels in areas of sarcomatoid morphology was observed ( Figure 2 R) (Wilcoxon signed-rank test, P = 0.0975) ( Supplemental Figure S2 B).
In the multivariate Cox regression proportional hazard model, a strong trend could be observed for elevated S100 at baseline (HR 1.78, 95% CI 0.90–3.54, p = 0.098) but not for the high-CCL20 group (HR 1.46, 95% CI 0.77–2.75, p = 0.244) regarding OS ( Table 5 ).
There was a positive relationship between FFM (derived from bioelectrical impedance) and TEE in the combined cohort of females and males ( p = 0.0004), which continued in females ( p = 0.03) but only detailed a strong trend in males ( p = 0.098) ( Figure 2 ).
However, we still observed a strong trend toward an association with higher BMI ( β = 0.52, SE = 0.32, P = 0.098) when compared with noncarrier or WT individuals ( Fig. 4D ).
0% ( p =0.013), and there was a strong trend toward better OS than patients with low S727 TILs H score ( p =0.099).
A strong trend in favour of the FLO-therapy was detected (Figure 2 A, p = 0.099), in terms of 5-year survival.
3B ) and a strong trend towards an increase in the expression of Igf2R mRNA in females ( Fig. 4B , p = 0.099) due to parental adolescent binge EtOH exposure.
For the biphasic group, loading resulted in a significant increase in metabolic activity within the tendon region and a strong trend ( P < 0.10) of reduced metabolic activity within the interfacial region.
2019 ), we also report those with a strong trend ( P < 0.1).
In patients with global dysfunction, LVD‐FMR patients displayed a strong trend for larger annular area (8.5±2.3 versus 7.8±2.1), antero‐posterior diameter (30.2±4.9 versus 27.4±4.0), and lower saddle‐shape depth (9.6±4.1 versus 11.3±3.1; P =0.1), but no differences in intercommissural diameters, circumference, or annular height compared to patients with global dysfunction and no MR.
The change in the fiber number of the right AF revealed a strong trend with a change in CIU/min without significant difference ( r = 0.7; p = 0.1).
No significant memory masking effect was observed for two of the participants (Participant 1 and 3) in Psychophysical Experiment 2, however Participant 2 showed a strong trend ( p <0.1) towards a masking effect in the MSR = 2 condition.
Although we observed a strong trend toward reduced medium AHP in neurons from Cond-1hr and Cond-24hr groups relative to Control, these changes did not reach statistical significance ( P < 0.1, 200–500 msec following current offset) (see Fig. 3 A).
At the completion of the trial the composite primary end point (death, cardiac death equivalent, or HF hospitalisation) did not differ significantly between groups, but there a strong trend to harm with the intervention (54.1% vs. 50.8%; HR, 1.13; 95% CI, 0.97–1.31; p=0.10) and a significant excess in total mortality (HR, 1.28; 95% CI, 1.06–1.55; p=0.01) and cardiac related mortality (HR, 1.34; 95% CI, 1.09–1.65; p=0.006).