“a strong trend”

Results Increased IL-22 in active MS patients First, using ELISA, we found that there was a strong trend ( p = 0.07) for an increase of IL-22 protein in the serum of 63 MS patients as compared to 13 HC (Fig. 1a ).

AR mRNA expression showed a strong trend toward positive correlation with Ki67 proliferation index ( r = 0.44, p = 0.07) and tumor volume ( r = 0.36, p = 0.06 for T1-enhancing regions; r = 0.40, p = 0.03 for non-enhancing FLAIR-hyperintense regions).

Next, we isolated EVs from additional plasma samples of the same subjects and 10 new subjects per group (Figure 2A ), and found a strong trend for an increase of miR‐122‐5p (FC = 1.84; P = .07) in severe asthma, and in all asthma subjects (FC = 1.96; P = .09) (Figure 2A ) by RT‐qPCR, confirming the sequencing results. miR‐191‐5p did not differ significantly among the groups, and miR‐3168 was not detectable by RT‐qPCR.

Findings from a prospective, double-blind, placebo-controlled trial of 60 adults undergoing cardiac procedures involving cardiopulmonary bypass demonstrated a strong trend toward a shorter hospital LOS for patients who received IVA (1 g every 6 hours for 4 doses) than for patients who received placebo ( P = 0.07). 26 The shorter LOS was attributed to reductions in overall opioid consumption and therefore opioid-related adverse events when IVA was used in an MMA regimen.

In addition, pain sensitivity for pinprick stimuli (MPS) was significantly reduced in the hand of NMO patients (p<0.05), accompanied by a strong trend towards MPS reduction in the feet (p = 0.07; Table 4 ).

1 g ), and a strong trend existed for correlation for EM patients (P = 0.07; Fig. 1 h ).

Including PS components in the final model, we observed a strong trend towards an association between age at admission and ICU mortality (OR: 1·04, 95% CI: 0·996–1·088, p=0·07).

In addition, RV ESP ( Figure 3I ) and dP/dt max ( Figure 3K ) were significantly reduced by COL treatment, with a strong trend of decrease ( P = 0.07) in ESPVR ( Figure 3J ) in the MCT group, while these parameters were unaffected in the CTL group.

Western blots showed that the V-SVZ of 4-month-old animals had a 55.5% decrease in PCNA expression (1 month, 0.18 ± 0,02 AU versus 4 months, 0.08 ± 0.01 AU, n = 4, p = 0.007, Unpaired t -test) that was accompanied by statistically significant downregulations of pAKT (27.4% decrease between 1 month, 0.51 ± 0.04 AU and 4 months, 0.37 ± 0.03 AU, n = 4 per age group, p = 0.03, Unpaired t -test) and p4EBP1 (51.5% decrease between 1 month, 0.68 ± 0.13 AU and 4 months, 0.33 ± 0.04 AU, n = 4 per age group, p = 0.03, Unpaired t -test) and a strong trend for pS6 (47.4% decrease between 1 month, 0.5731 ± 0.1223 AU and 4 months, 0.30 ± 0.05 AU, n = 4 per age group, p = 0.07, Unpaired t -test) ( Figure 1F ).

Interestingly, when data from all the patients irrespective of their prior CDI history were included in the analysis, CCL-5 was the sole biomarker that showed a strong trend ( P = 0.07) toward association with 90-day recurrence.

Among Sami adolescents, there was a strong trend (p = .07) of more suicide attempts in adolescents not speaking the Sami language ( Table 3 ).

Interestingly, there was an apparent initial decrease in activity over the first 4 days, with a strong trend for less distance covered in the EXER VITD mice on day 4 ( p = .07, Fig. 3 A ); however, the mice quickly recovered.

Significant associations were found between cerebral hypoperfusion with decreased volume for the temporal lobe ( F (1, 41) = 12.92, P = 0.01; β = 0.25) and a strong trend for the parietal lobe ( F (1, 41) = 3.56, P = 0.07; β = 0.19).

Further, there was a strong trend that gender influenced the response of inflammation to higher CVF, (p = 0.07); specifically, in the high fitness group only 3% of males had an elevated hsCRP compared to 26% of the females.

The forced swim test showed significantly decreased immobility time in Dagla KO mice, while a much smaller cohort of Cnr1 KO mice showed a strong trend ( P = 0.07) toward a similar decrease.

With the exception of a strong trend towards clustering older patients in the high LTS group (67±3 vs. 59±2 years old; p=0.07), patients with low or high LTS scores did not differ in obvious vascular or medical risk factors that would otherwise identify them as high risk for future cardiovascular events or that might influence the regenerative performance of EDCs.

Evaluation of human muscle biopsies revealed a strong trend for depressed expression of HO-1 (Fig. 3e , P < 0.07) (although these data must be interpreted with caution, in light of small number of samples and variability of biopsy site).

T-cell density and hypointense volume changes exhibited a strong trend toward a positive correlation 19 days after CT26 tumor inoculation (r = 0.57, P = .07, Figure 3 M ).

However, a strong trend ( p = 0.07) was noted in fatigue rate during a 60-s Wingate anaerobic power test.

When they subdivided the patients with midwall fibrosis into groups with scar < 4.8% and scar > 4.8%, Kaplan-Meier analysis showed a strong trend towards significant difference in outcome between the two groups for their primary endpoint of all-cause death and cardiovascular hospitalization ( p = 0.07).

Moreover a two-factor ANOVA, analyzing the interaction of sex and knockdown on this parameter did not indicate a significant effect of sex (F (1, 31 ) = 0.02, P = 0.9), or an interaction (F (1, 31) = 0.03, P = 0.9) on food seeking while indicating a strong trend for an effect of knockdown (F (1, 31) = 3.513, P = 0.07).

ER-negativity had a strong trend in Cohort A (HR 2.8, 95 % CI 0.9–9.1; p = 0.07) and was significant in Cohort B (HR 5.0, 95 % CI 1.1–10.0; p = 0.04).

2009 ), although a third test reported a strong trend ( P = 0.07) for an improvement in the supplemented group (2,000 m rowing; Baguet et al. 2010a ).

Myonuclear domain size, defined as the fiber CSA per nuclei, was maintained in type I (pre: 1409.6±72.5 μm 2 /nuclei; post: 1341.1±61.5 μm 2 /nuclei) and in type II fibres (pre: 1799.6±96.7 μm 2 /nuclei; post: 1987.1±111.8 μm 2 /nuclei), with an increase in the number of nuclei per muscle cross section of type I fibres (pre: 3.9±0.2; post: 4.6±0.2; p<0.05) and a strong trend for an increase in type II fibres (pre: 3.6±0.2; post: 3.9±0.2; p = 0.07) observed with training ( Fig 2A and B ).

There was a strong trend toward increased CS total activity of the diaphragm compared to TA in both control and mdx muscle (20%; p = 0.07), however there were no significant differences in any of the other CS measures between muscles (CS before , CS after and CS before :CS after all p >0.05).