“a strong trend”

Expression of miRNA-221 was not correlated with OS in the present patient cohort, however, in patients without neoadjuvant treatment miRNA-221 positive tumors showed a strong trend towards shortened OS ( p = 0.070) with a median OS of 64.0 months in miRNA-221 negative patients (95%CI not calculable) compared to a median OS of 22.1 month (95%CI 13.3–30.8 months).

There was a strong trend to lower ablation times in the Cartomerge group, overall RF time (3,292 s vs. 4,041, p = 0.07).

There was a strong trend for deeper tillage on Large farms ( P = 0.070) but the difference in average tillage depths between farm size groups was very small.

A significant main effect of day [ F (2.5, 54.1) = 13.5, p <0.001], and a strong trend toward a sex effect [ F (1, 20) = 3.9, p = 0.07] were found, but there was no sex by day interaction.

Nevertheless, a strong trend here (corrected P -value = 0.07) was also evident ( Fig. 3A ).

Chronic 2‐MPPA reduced GCPII activity in dlPFC tissue The 2‐MPPA‐treated group showed a strong trend for reduced GCPII enzyme activity in dlPFC compared to the vehicle‐treated controls ( p = 0.07; Figure 4A ).

By day 49 post-stroke, a strong trend towards an increase in CD206-expressing cells was observed, which is indicative of macrophage involvement in tissue remodeling and homeostasis (*Fig. 5g, h , p = 0.07, t -test).

The mean CES-D scores were not significantly different between those who increased their PA levels and those whose PA levels remained the same or were reduced although a strong trend was in evidence (6 versus 14, p < .07).

A strong trend toward better results in patients with lower iPWV was found without reaching statistical significance ( P =0.07) (Figure S2 ).

There was a strong trend for cages with 2 or more plants to have higher fruit-to-flower ratios than those with 1 plant (Mann–Whitney U test, P = 0.07), although our low sample size for locations with 2 to 3 plants (rare at these sites; n = 8) may explain the lack of significance at α = 0.05.

When analyzing several markers of mitochondrial biogenesis, we found a strong trend ( p = 0.07) towards upregulated COX-1 3 h after HIHVT ( Fig 5B ).

Similarly, patients with multiple lesions and histologic high-grade DCIS had a strong trend of upstaging to invasive carcinoma ( p = 0.07).

The other coprimary endpoint, quality of life measured by Minnesota Living with Heart Failure questionnaire showed a strong trend ( P = 0.07) for improvement by both diet and ET.

EC and phosphorylation potential were not statistically significantly different ( Figure 7 A,C); however, both showed a strong trend ( p < 0.07) for significant differences between groups, which in both cases appears to have been driven by a decrease only in the high-fat group, which is consistent with the decreased ability of the heart to produce energy to improve salvage and sustain function.

Furthermore, we found a strong trend in the interaction between negative olfactory stimuli, Time, and Group, O x T x G (F 1,30 = 3.38, p = 0.07; η p 2 = 0.10), with the control group (CG) feeling emotionally worse during the occurrence of negative odours on the second measurement than the training group (TG).

In particular, there was a strong trend for an increased number of streamlines within the thalamoprecentral segment in patients relative to controls (p = 0.07, Table 3 ).

The differences between both groups were not statistically significant, but a strong trend was indicated (p = 0.07; Kruskal- Wallis rank sum test).

Prior to food deprivation for behavioral analysis, there was a strong trend for TgAD rats to weigh more than their WT counterparts (t [8] = 2.05; p = 0.07; Fig. 2 B).

The difference in weight between treatment groups was not significant although a strong trend was present (p = 0.070).

Radiographically, in comparison to calcitonin, there was a strong trend towards teriparatide for higher fusion rates (86.7% vs 56.3%, p = 0.07) [ 21 ].

The only significant aspect was the BMI value ( p < 0.001 expected 1.18) regarding years of service since it showed a strong trend ( p = 0.07 expected 5.43), while age was not considered significant ( p = 0.4 expected 1.003). 4.

Results Increased IL-22 in active MS patients First, using ELISA, we found that there was a strong trend ( p = 0.07) for an increase of IL-22 protein in the serum of 63 MS patients as compared to 13 HC (Fig. 1a ).

The findings were confirmed by qRT-PCR which demonstrated a strong trend towards increased ARG1 following injury ( P = 0.07), accompanied by a significant decrease in NOS2 ( P < 0.001; Figure 2C ).

AR mRNA expression showed a strong trend toward positive correlation with Ki67 proliferation index ( r = 0.44, p = 0.07) and tumor volume ( r = 0.36, p = 0.06 for T1-enhancing regions; r = 0.40, p = 0.03 for non-enhancing FLAIR-hyperintense regions).

Next, we isolated EVs from additional plasma samples of the same subjects and 10 new subjects per group (Figure 2A ), and found a strong trend for an increase of miR‐122‐5p (FC = 1.84; P = .07) in severe asthma, and in all asthma subjects (FC = 1.96; P = .09) (Figure 2A ) by RT‐qPCR, confirming the sequencing results. miR‐191‐5p did not differ significantly among the groups, and miR‐3168 was not detectable by RT‐qPCR.