“a strong trend”

A strong trend for a genotype x treatment interaction was noted ( p = 0.059) ( Figure 3H ).

There was a strong trend for higher temperatures in the homes of the older age group (p=0.059).

Exposure to a Diet Enriched with Fat and Cholesterol Results in the Deficient Hippocampus-Dependent Performance in the Fear Conditioning and Pellet Displacement Tests In the fear conditioning test, in comparison to that in control mice, the number of “good learners” defined by the percentage of time spent with freezing ≥ 50% at the memory recall session was significantly diminished in the dietary-challenged group ( p = 0.017, Fisher's exact test, Figure 5(a) ); also, there was a strong trend to a decreased duration of freezing in this group ( t = 1.96, p = 0.059, t -test, Figure 5(b) ), suggesting reduced contextual memory in mice housed on the high-cholesterol and fat-containing diet.

A strong trend for a lower wear rate for the asymptomatic cohort compared to the symptomatic cohort was observed (p = 0.059).

In a randomized trial of 508 eligible patients, memantine in addition to WBRT (20 mg/d, starting 3 days prior to WBRT for 24 weeks) showed a strong trend towards less decline in delayed recall at 24 weeks when compared to WBRT without memantine ( p = 0.059).

Regarding HOMA index, a strong trend ( P = 0.059) in reducing insulin resistance status was seen in the trained animals when compared with sedentary groups, REF (0.29 ± 0.05); LS (0.32 ± 0.06); ET (0.21 ± 0.05); LS+ET (0.20 ± 0.03); diet ( P = 0.872); training ( P = 0.059), and interaction ( P = 0.683).

At P1, two cytokines Fas-L (2.79-fold, P =0.027) and IL-6 (2.35-fold, P =0.031) were significantly upregulated while there was a strong trend towards a decrease in the growth factor bFGF (0.38-fold, P =0.059).

Along these same lines, WT-PNPLA3 expressing mice displayed a strong trend ( p = 0.059) for increased left ventricle anterior wall thickness during diastole (LVAWd) post 16 weeks of MASH diet, which was not observed in either GFP or PNPLA3-I148M expressing mice (Fig. 4 F).

A statistically significant link between AMU and AMR was further determined for sulfonamides ( p = 0.010) and tetracyclines ( p = 0.042), and a strong trend for such a link was also found for fluoroquinolone use and quinolone resistance (all when classified into tertiles; p = 0.059; Table 2 ) among commensal E. coli .

This revealed a strong trend for the effect of mask condition ( F (1, 8) = 4.825, p = 0.059; no main effect of error location ( F (1, 8) = 3.549, p = 0.096; and no interaction ( F (1, 8) = 0.138, p = 0.72).

Principal coordinate analysis revealed a strong trend towards separation of microbiota communities between sham and CIH-exposed animals ( p = .059; Fig. 7 f).

Specifically, we observed greater lesion length, as well as a strong trend ( p = 0.059) towards reduced white matter sparing, in Cl-amidine treated female mice relative to vehicle controls.

However, univariate analysis did show a strong trend significance with a negative effect of preoperative RDW ( P = 0.059).

However, IL-4-treated TBI PPARγ OPC-cKO mice showed significantly improved cognitive performance (Supplemental Figure 2(b) to (d), Escape latency, p < 0.0001; Quadrant time, p = 0.0321) or a strong trend toward improvement in spatial memory (Supplemental Figure 2(d), Platform crossings, p = 0.0590) compared to vehicle-treated TBI mice.

A strong trend for an increase in the Fazekas scores in Fabry compared to controls was observed (1.05 ± 1.05 vs. 0.5 ± 0.7, respectively, P = 0.059; Fig 4a ).

Gfap mRNA levels were analyzed by non-parametric test and Kruskal–Wallis showed a significant effect of lesion in WT ( p = 0.013) and KO ( p = 0.000), with a strong trend towards higher basal levels in KO than in WT ( p = 0.059).

For spheroid staining, Donor 2 revealed a significant reduction in BMPR2 expression compared to Donor 3 ( p = 0.007), with a strong trend in reduction in relation to Donor 4 ( p = 0.059) and a diminished though evident trend in comparison to Donor 1 ( p = 0.106).

In further analyses, repeating the ANCOVA analyses including BDNF levels at week 5 the association was reduced to a strong trend (F = 3.07, p = 0.059, partial ŋ 2 = 0.08).

As shown in Figure 6 B , when looking at the total number of cells expressing DeltaFosB in the LC, the two-way ANOVA showed a strong trend (n.s.) for an effect of alcohol, which was again independent from sex (Ethanol: F (1,28) = 3.87, p = 0.059, n.s.; Ethanol × Sex: F (1,28) = 0.69, p = 0.41, n.s.); when sexes were pooled together, IA2BC overall caused a 35.6% increase in LC cells expressing DeltaFosB (Student's t test: t (30) = 2.09, p ≤ 0.05).

Kruskal–Wallis ANOVAs on z-scores showed significant group differences in the percentage of the same (H = 8.14, p = .02), closer-up (H = 7.32, p = .03) and a strong trend in the BE score (H = 5.66, p = .059).

There was a strong trend towards reduced outliers for inclination of the acetabular component (0% versus 8%, p = 0.059), but this did not reach statistical significance.

By contrast, after 25 days of inosine injections and continuing HFD feeding, we observed a strong trend for reduced fasting blood glucose levels ( P = 0.0592) (Extended Data Fig. 3m ).

A statistically significant difference resulted for TRZ30 vs PLB at visit 4 (day 28) [95% CI − 1.57, − 0.15; p = 0.0182) and a strong trend was observed at visit 5 (day 35) [95% CI − 1.51, 0.03; p = 0.0593] and visit 9 (day 63) [95% CI − 1.41, 0.04; p = 0.0630] (Fig. 3 ).

In Cox regression analysis, there was a strong trend toward reduced mortality risk (HR = 0.4, 95% CI = 0.16–1.0; p = 0.0593). 3.3.3.

A strong trend was observed between changes in divergence and corresponding changes in longitudinal diastolic strain rate between examinations (ρ = −0.58, p = 0.0595).