“a strong trend”

In addition, patients with central conduction deficit showed a strong trend towards having a higher grade of stenosis compared to patients without central conduction deficit (grade II (I-II) vs grade I (I—I), p = .055).

In addition, there was a strong trend for a reduction in frequencies of IFN-γ + CD8 + T cells in JSLE ( Fig. 1b , P = 0.055) and a significant reduction in TNF-α + CD8 + T cells in JSLE ( Fig. 1c , P = 0.009) compared to HC.

Univariate Cox regression for OS (Table 3 ) revealed that poor baseline ECOG PS (2–3) was associated with worse survival (HR 1.72, 95% CI 1.02–2.92, p = 0.04), and major mutations showed a strong trend toward improved survival (HR 0.44, 95% CI 0.19–1.02, p = 0.055).

After removing two outliers from the control group, C6 and C16, there was only a strong trend towards significance (2-tailed Mann–Whitney U test, p = 0.055, n = 48).

There were no significant differences in the expression of p-eNOS ( p = 0.41) or total eNOS ( p = 0.15), though there was a strong trend towards a decreased p-eNOS to eNOS ratio ( p = 0.055) in the HYP group compared to NOR.

2 B–D) were not different between groups, there was a strong trend ( p = 0.055) toward group differences in the amount of time spent in the center of the OF.

At 24 h there was also a strong trend to an increase in quinolinic acid levels (P = 0.055).

However, there was a strong trend toward greater likelihood of TP53 alterations in nonresponders (Fisher’s exact test P = 0.055).

The Variable group showed a strong trend toward a positive correlation ( r = 0.37, p = 0.055), but there was no correlation in the Constant group ( r = –0.23, p = 0.24).

Patients receiving lactated Ringer's solution also had a strong trend of lower concentrations of plasma hydroxyisocaproic acid (interaction P = .055), a leucine degradation metabolite, and smaller decreases in phospholipid breakdown anti-inflammatory metabolite concentrations, namely 15-ketoeicosatetraenoic acid (15-oxoETE, interaction P = .063).

As TCF1 was also expressed by cancer cells, we assessed its prognostic impact and found that increased percentage of TCF1 + in cancer cells was associated with a strong trend for a worse DFS in the TC (HR:2.5, 95%CI:1.0-6.5 p=0.055), a trend that became significant when the TCF1 positivity was assessed in the IF (HR:2.1, 95%CI:1.0-4.4, p=0.045) ( Table 1 , Figure 1D ).

Regarding RFS, IPI score emerged as a significant predictor of shorter RFS (HR = 1.633, p = 0.012), while response to therapy showed a strong trend toward association with RFS ( p = 0.055).

RT-qPCR confirmed significant reduction of FC-induced RNA increase in Top3β-KO mice for Arc, Egr1 , and Npas4 ( p < 0.05); and a strong trend of reduction for c-fos ( p = 0.055) (Supplementary Fig. 6a-d ).

A main effect emerged of semantic relation on RTs [ F (1, 20) = 5.26, p = .033, η p 2 = .208], with targets responded to faster on SR objects (865 ms) than on NR objects (882 ms), and a strong trend for a main effect of exposure duration, with participants finding the target faster after 1,250 ms [ F (1, 20) = 4.14, p = .055, η p 2 = .171; 886 and 862 ms for the 750 ms and 1,250 ms durations, respectively], but no interaction between the two [ F (1, 20) = 2.31, p = .144, η p 2 = .103].

Compared to the placebo group there was also a strong trend for a higher decrease in the bilberry/red grape group for myocardium specific CK (CK-MB) ( p = 0.055) decreasing from median 9.8 U/L at baseline (U/L) to 9.0 U/L (Table 5 ).

We observed a strong trend for an increase of FAK phosphorylation (+70 %; p = 0.055) (not shown).

The mammary epithelium of untreated Mcs5a -resistant congenic rats as compared with susceptible congenic control rats had equal percentages of CD3 + T cells (Figure 5a ), of which CD4 + and CD8 + T cells were equal as well, but γδTCR + T cells showed a strong trend ( P = 0.055) toward overabundance (Figure 5a ).

In contrast, mutations in ASXL1 were more prevalent among newly diagnosed patients ( p = 0.04), and a strong trend for a higher prevalence of TET2 mutations among this cohort as well ( p = 0.055).

PV cell number in the hippocampus One-way ANOVA showed a strong trend for a significant difference in total PV cell count across treatment groups in the DHP ( P =0.055).

A priori planned comparisons using one-tailed paired t-tests revealed significantly higher scores for dilemmas with humanized than neutral persons on the H scale (H umanized : M = 60.7, SE = 2,5, N eutral : M = 56.2, SE = 2.5, T(53) = 2.36, p = 0.011), a strong trend towards higher scores on the PD scale for dilemmas with H umanized persons (H umanized : M = 59.5, SE = 3.3, N eutral : M = 56.0, SE = 2.6, T(53) = 1.63, p = 0.055), and a weaker trend towards higher scores on the EC scale (H umanized : M = 56.4, SE = 2,5, N eutral : M = 53.8, SE = 2.5, T(53) = 1.30, p = 0.099).

The association with “extreme” symptoms showed a strong trend (OR = 3.16) but was borderline distinct (p = 0.055), reinforcing the substantial impact of metabolic health on joint pathology.

Finally, these metabolic changes were associated with a strong trend towards decreased cardiac function (p= 0.055) ( Figure 7G ), with a significant decrease in heart rate following ML348 treatment ( Supplementary Figure 6 ).

The female vicarious group showed a strong trend toward reduced grooming ( p = 0.055).

There was a strong trend towards a drug effect on adolescent locomotion (F(5,67) = 2.298, p = 0.055), primarily driven by quinpirole, the only treatment significantly different from saline (p = 0.031).

Only Hispanic ethnicity was independently associated with definite MASH, with a strong trend for presence of PNPLA3 allele variants (OR 1.59, p = 0.055).