“a strong trend”

Compared to HST, CHP exhibited a strong trend of lipid downregulation, while OAS, LCG, and YXP showed upregulation trends.

7 The Baltimore Longitudinal Study of Ageing also found a strong trend towards reduced relative risk of AD in patients treated with DHP CCBs, with no lowered risk observed in the non-DHP CCB treatment group. 8 Furthermore, nilvadipine has been shown to have favourable effects on cognitive function with stabilisation of cognitive decline and reduced conversion to AD in patients with hypertension with mild cognitive impairment. 9 A study by Kennelly et al 10 provided preliminary evidence suggesting the potential efficacy in the treatment of AD.

In addition, there has been a strong trend toward the procedure being performed in older patients with less favorable anatomy and greater comorbidities with attendant less favorable results and substantially higher complication rates 53 , 54 ; this may reflect waning of experience by operators as well as the greater inherent risk in these patients.

Even in patients undergoing chemoradiation, surgery was the only prognostic variable that significantly affected survival in stages I–II patients (HR 0.63) and showed a strong trend in stage III (HR 0.77) patients.

However, we do observe a strong trend for the two matched samples ( Figures 4B, D , and Supplementary Figure S4A ) supporting our main claims above.

As can be seen in Fig 2G , muscle mitochondria from mice from the early group had a strong trend for an increase in free radical leak under both state 2 and 3 conditions ( Fig 2G : G + M, G + M + ADP + Succ).

The static single measurement of the methylation status of both SEPT9 and SHOX2 showed a strong trend for hypermethylation in PCa patients but did not reliably distinguish between healthy individuals and men suffering from PCa.

In line with this hypothesis, vividness of reward-based imagined scenes was higher in the reward condition at a strong trend level ( Fig 2 ), indicating that reward association led to greater clarity and vibrancy of the imagined scene.

More severe phenotypes at the lateral femur, medial tibia, and medial femur were significantly correlated with greater mass (p = 0.011, 031 and 0.003, respectively). The lateral tibia, although not significantly different (p = 0.051), appeared to have a strong trend based on the one-way ANOVA.

PFS HR for arm B was 0.65 (95% CI: 0.41–1.03), therefore not significantly worse than arm A and with a strong trend to superiority towards arm A.

Due to the progression conducted in LC, there is a strong trend in recent years to incorporate these techniques for protein separation without affecting their conformational structure, and consequently their biological activity [ 21 ]. 2.1.

brevirostris , an edge forager with a strong trend towards open space, were almost identical.

It showed a strong trend in the LF range with the active tumor patients exhibiting a higher gain than the LS patients.

Secondly, a strong trend toward the administration of both Mass and 793B vaccine at 1 day of life emerged during the last year in Italy.

By applying this cut-off value (9.82 relative units), we observed a strong trend towards an impaired survival in patients with miR-107 levels > 9.82, however the difference failed statistical significance (p = 0.119).

However, after accounting for mortality as a competing risk, only a strong trend toward risk reduction was observed, which did not reach statistical significance (aHR 0.74 95% CI 0.55–1; P −0.053) (Supplementary Table S3).

When reviewing the annual submission rate of all cases microscopically consistent with viral papillomas with transformation toward a malignant phenotype in comparison to our overall submissions, there is a strong trend toward a 2–3 fold increase of the number of such cases between 2006 and 2014.

The minimal KEi EDV and the proportion of in-plane KE significantly reduced from normal EF in healthy controls to MI patients with preserved EF and then had a strong trend to increase with decreasing EF – a finding that at first seems paradoxical.

Cavβ1b was able to significantly increase the surface pool of WT-Cav1.2-HA (10145 +/-790 ALUs, p = < 0.05 ANOVA), and there was a strong trend towards increased surface expression of A39V-Cav1.2 (10109 +/-842 ALUs), however, this effect did not reach statistical significance (also see Additional file 2 : Figure S2).

claveryi soil mycelium did not follow a strong trend or growth pattern.

Although the difference between the combined model and the SAA kinetics model at 12 months did not reach statistical significance, the p value was borderline (0.051), suggesting a strong trend toward improved prediction.

There is a strong trend of a direct correlation between adenocarcinoma (faceted square) and large cell carcinoma (triangle) and a highly significant inverse correlation with NSLC at the upper end (pentagram) and small cell cancer (rectangle) at the lower end ( Table 3 ).

As for the RV, there was a strong trend between suggesting that RV dilatation and dysfunction were associated with worse outcomes.

Except for one response, none of the responses obtained were supported by half or more than half of the participants to be considered as a strong trend in the data.

Based on the scatter plot of the numbers of "missing" images and "forgotten pictures" throughout the study period, there did not appear to be a strong trend in either "missing" images or "forgotten pictures" throughout the study.