The biliary-like ampullary group, which showed a strong trend for shorter survival, showed increased expression of activation-specific markers in several kinase signaling pathways, including the PI3K-AKT (P-AKT Ser473, P-GSK3 Ser21, P-P70S6K T389, P-mTOR S2448, and P-FOXO3a), RAS-RAF-MEK-ERK (P-MAPK, P-MEK), and JAK-STAT (P-STAT3 S727) ( Table S2 ).
Hispanics showed a strong trend in transitioning to PhD programs (67%) versus just 33% of non-Hispanics.
This indicates a strong trend towards neutrality (Ka/Ks ratio of 1) for substitution rates at synonymous and non-synonymous sites for GLI gene family.
In addition to marker analysis, our blood flow assays showed that the ischemic myocardium of the HEV group exhibited a significant increase in myocardial perfusion during rapid ventricular pacing, as well as a strong trend toward increased myocardial perfusion at rest.
Multivariate analysis showed PSAd to be an independent factor for predicting tumour upgrading on repeat biopsy, whereas it showed a strong trend to predict PSAV on follow-up.
oncern for others”; and outbreaking situations as “excessive burden, difficulties relevant to personality defaults, interpersonal conflicts, maturational crisis”; attitudes toward treatment as “antidepressants are almost ineffective, intensive psychotherapy is needed”; clinical course as “they have a strong trend of becoming chronic and prolonged”; age as “two age ranges, one from late teens to 20s, the other in 40s or 50s”; physical features as “no characteristics”; life history as “already showed neurological symptoms or tendency of personality neurosis before onset of depression”; family image as “no cha
Currently, there is a strong trend towards to organic food and the consumption of lean meats from goats and sheep that reared on pasture.
The ANOVA estimates appear to have a strong trend where τ 2 is smaller than expected, reflecting the tendency of the ANOVA estimate to favor σ 2 at the cost of shrinking τ 2 to zero if necessary (we saw this same pattern in fig. 2 ).
We also saw a strong trend where the probability of hypo-methylation increases with increasing number and density of CpGs in the cluster.
[ 19 ], which included several tumor types, there was no significant prognostic impact of TIL expression in brain metastases in the entire population, and there was a strong trend towards better survival in brain metastases from melanoma with high levels of PD-L1 [ 19 ].
These effects were associated with decreased muscle expression of the putative uncoupler adenine nucleotide translocase, but also a strong trend towards decreased UCP3 expression [ 44 ].
While the low dose (0.27 g kg −1 ) effectively decreased the TNF‐α level (66.13 ± 15.93 pg mL −1 , p = 0.0005, Cohen's d = 1.88), its effect on IL‐6 reduction (4.51 ± 0.27, p = 0.058, Cohen's d = 0.91) showed a strong trend but did not reach statistical significance.
Contrary to our expectation, we do not see a strong trend towards an enrichment of repetitive elements among young genes.
Experts’ perceptions of the popularity of plant-based and insect-based APF Research investigating haute cuisine restaurant trends suggested that expert panels (selected on the basis of their entry on the official Michelin Guide website) predict that alternative proteins (insect- and plant-based) will become a strong trend in major European restaurants [ 47 *].
As expected, all stages show accelerated kinetics with increasing temperature, demonstrating a strong trend despite the narrow temperature window.
The percentages of triple-negative IL-2 − IFNγ − TNFα − T lymphocytes were also markedly increased in CD8 + T cells and with a strong trend in CD4 + T cells (Fig. 5 b).
In addition of new methodology to remove traces of palladium or other catalysts, there is a strong trend to develop more “green” or environmentally friendly approaches to minimize potential toxicity to the ecosystem.
Although these outcomes are statistically non-significant, there is a strong trend toward a reduction in NEC and an improvement in all anthropometric measurements.
Across participants, Z-scores were strictly positive in 69–75% of the trials in all ROIs, indicative of a strong trend away from the surrogate data (Fig. 4b ).
We examined this phenomenon further by looking at siRNA distributions around individual genes, and we noticed a strong trend for 24-nt siRNAs to be concentrated very close to gene ends, as illustrated by a cluster of genes in Figure 1A .
Similarly, recent studies have revealed transcriptomic differences between young and old microglia during the post-stroke recovery phase (14 days post-stroke), with young microglia also showing a strong trend toward the upregulation of gene expression after stroke compared to that observed in aged microglia [ 80 ].
Central ambulatory systolic pressure, measured with an oscillometric cuff, shows a strong trend toward a closer association with left ventricular mass and hypertrophy than brachial office/ambulatory systolic pressure [ 17 ].
Nevertheless, we observe a strong trend relating city size to automation impact that is robust to errors in the automatability of individual occupations and occupational subsampling.
However, although we did not observe significant group differences in psychophysical thresholds in the present study, we did find a strong trend toward group differences in hearing acuity when we used a permutation test to search for effects across both ears and all frequencies.
We measured a strong trend for reduced synapse numbers in the aged injured animals when compared to the age-matched sham animals ( Figure 5 A).