“a strong trend”

There was a strong trend of decreased PROX1 promoter DNA methylation in DNPC tumors as well, with two of three samples showing greatly decreased DNA methylation ( Figure 3A ).

There is a strong trend for studies to combine data from multiple GWAS studies into a meta-analysis to (1) validate previous findings ( 2 ), (2) expand findings from single populations to universal effects ( 3 ), and (3) identify novel gene effects ( 1 ).

The Japan-specific dosage of rivaroxaban was found to be non-inferior to warfarin with respect to the incidence of major and non-major clinically relevant bleeding, and was associated with a lower incidence of intracranial bleeding and a strong trend for a lower incidence of stroke/SE compared with warfarin [ 9 ].

On the other hand, there is a strong trend to discriminate malignant cells from the healthy ones by adjusting the threshold for CAR-T cell activation.

Subgroup analysis showed a strong trend in both subgroups, reaching significance in the surgical group even though it was not powered for a separate analysis.

Basically, without this rep there at least is a strong trend that there is a difference in secretion without EtOH stimulation.

Only in the GLU model was a strong trend present; as the quality of the diet increased, the deltas between seniority groups increased.

However, neither the Resilience nor the Food Waste metrics show such a strong trend (Table 1 ).

In the synaptoneurosomal fraction, similarly to what was found with RU486, compared to either naïve or trained rats injected with IgG, anti–BDNF significantly lowered the levels of pERK1/2 and pPLCγ without affecting those of ERK1/2 and PLCγ, and resulted in a strong trend toward a decrease, although not significant, of pAkt without changing Akt ( Fig. 4a and Supplementary Table 4 ).

In agreement with the mRNA expression data, there was a strong trend for RagA protein abundance to be higher than RagB protein abundance in rat skeletal muscle.

Interim analysis of overall survival (OS) showed a strong trend in favor of the pertuzumab plus trastuzumab plus docetaxel regimen [2] .

Importantly though, we found significantly higher APTw values in PET-positive areas in FHT in GB and a strong trend towards higher APTw values in FET hotspots even in the FHT in LGG, where APTw was generally low.

Importantly, there is a strong trend of higher accuracy with increasing confidence level.

7 illustrates the data at 60 °C for which a strong trend of decreasing conductivity with MW is observed.

The place of chemotherapy remains to be defined: recent results presented at the annual meeting of American Society of Clinical Oncology (ASCO) 2012 demonstrated a significant radiological PFS benefit and a strong trend in overall survival benefit of abiraterone plus prednisone over placebo plus predisone for patients with asymptomatic or mildly symptomatic mCRPC. 58 Other phase 3 studies exploring the impact of docetaxel based chemotherapy when used in earlier stage have shown positive biological PSA responses at the ASCO 2011 meeting. 59 – 61 Clinical events are strongly awaited.

There was also a strong trend to less IgE-associated eczema, but there was no difference in “any IgE-mediated disease” [ 83 ].

Our interfacial simulations reveal that while the double-layer structure is dependent on cation identity, the free energy of nitrate physisorption to the cathode lacks a strong trend with the cation identity.

The current prices have a strong trend of reduction [ 33 ].

There was also a strong trend towards a reduction in the risk of kidney failure in patients with CKD defined as eGFR less than 60 ml/min/1.73 m 2 , compared with those with an eGFR greater than 60 ml/min/1.73 m 2 .

5 ), it is possible to observe a strong trend for plants exposed by the tank-mixture dicamba + potassium glyphosate + lecithin + propionic acid (D + R + L).

When the AA and NonAA cohorts were divided into PD-L1 positive and negative or sTILs high (≥30%) and low (<30%) biomarker groups, respectively, the PD-L1 positive and sTILs high groups showed a strong trend for better recurrence-free survival in NonAA patients.

However, there was evidence of a strong trend in group differences for prescription of SSRIs.

Starting at 24 hours, we observed a strong trend for a greater rate and number of recoverable bacteria by WU2 versus ∆ pspA .

The waterfall plot similarly showed a strong trend between PDC AUC values and the clinical tumor response to EGFR- or ALK-TKIs ( Figure 3 B).

Exposure to MMC led to a statistically significant increase in the 8-oxodG levels in the PFC tissues of male mice (p=0.016), while the PFCs of MMC-exposed female mice showed a strong trend towards an increase in 8-oxodG levels, but the difference did not reach statistical significance (p=0.146) (Figure 3 A ).