“a strong trend”

While GD2 and GH at 10 μg/mL showed a strong trend of IFI44L induction, the most robust and significant effects were centered on ISG15 , a core ubiquitin-like effector in the interferon response [ 112 ].

TNFα-producing BM and splenic monocytes/macrophages (CD11b + ) ( Supplementary Figures 7A and 7B respectively) were also significantly increased in reconstituted mice relative to WT mice, but despite a strong trend fell short of significance relative to TCRβ KO controls.

When excluding patients with an alcohol-related diagnosis, LDL was not significantly associated with fracture risk in type 2 diabetes patients, however, a strong trend was present.

Hepatocyte-specific knock-out mice showed a strong trend towards lower pathologic collagen deposition, whereas HSC-specific knock-out mice did not show a difference in collagen deposition compared with control mice ( Figure 6 , A, C ).

This observation can be explained by a strong trend towards urbanization in the city of Nouna, with an increase in the population and their purchasing power.

As in other studies leukopenia was the most common hematologic toxicity and our analysis showed a strong trend for higher grades of leukopenia in patients treated with CDDP/5FU in the ITT-analysis and significantly higher grades of leukopenia in patients treated with CDDP/5FU in the PP population.

Mecp2-OE mice treated with Veh exhibited a strong trend toward impaired social cognition compared with WT mice, based on the preference index ( Fig. 5, K and L ).

Similarly, we observed reduced 50 Hz ASSR in both Grin2a KO and Hets at 6 months and a strong trend towards reduced 40 Hz ASSR in Akap11 KO at 3 months (Fig. 5 ).

However, as was the case for oxygen, there was a strong trend of increasing glucose concentration within discs of decreased disc volume, with the initial culturing concentration of glucose reducing approximately 62% in the NP of discs from Group 1 and approximately 25% in the NP of discs from Group 3.

These discoveries suggested a strong trend towards progression and metastasis in our patients.

Investigation into the subcellular localization of AAV revealed a strong trend toward shifting from the cytosol to the nucleus upon HCQ treatment.

This interpretation is consistent with our flow cytometry data, which showed a strong trend toward RSV inhibition at 16 hpi that became statistically significant by 24 hpi.

We found a strong trend for both an increased proportion of patients in either systolic or diastolic control, and an increased proportion in both diastolic and systolic control.

mangle , this may be tied to salinity, as both also showed a strong trend with porewater salinity, suggesting that changes in urban hydrology may be driving the observed compositional metrics.

Furthermore, a recent cost-benefit analysis comparing wire cerclage and rigid plate fixation demonstrated a strong trend toward reduced sternal wound complications with plate fixation [ 16 ].

3e, f ), while for OS only a strong trend could be observed (p early =0.062, p late = 0.066) towards higher levels in patients who survived longer.

Lastly, the results from the medical records review highlighted a strong trend for clinicians to focus on the biomedical aspects of HIV care whilst paying little attention to holistic issues such as disability.

For device 3, however, there was a strong trend towards smaller B1 field in cranial direction, with the areas in the corner showing a B1 field reduced by up to 35% compared to the measurements in absence of a device.

There was a strong trend for reduced NOP mRNA in the bed nucleus of acute and repeated restraint groups, although there were no other significant changes seen.

The difference showed a strong trend but did reach statistical significance ( Figure 4(a) ).

In addition, also in the SQ population a strong trend towards a reduction of TWOS/IS was observed when devices were updated with the new SMR8 software (SQ-SMR8(−): 13.4%, n = 11/82 vs.

In particular, 0.2% DS sulfated carriers showed a strong trend towards decreased metabolic activity on day 0 and after 14 days, suggesting a sulfation-dependent decrease in cell performance ( Figure 5 b). 2.6.

There was a strong trend for an independent association between the presence of OSA and triglycerides/HDL ratio.

However, a strong trend was found between H γ and the severity of aging, with a greater H γ value indicating to a more aged binder ( Fig 17 ).

The subgroup analysis revealed a strong trend that 40 μg of teriparatide had a more prominent positive effect on radiographic callus formation than 20 μg.