“a strong trend”

The pooled results showed a strong trend, but no significant difference was observed between TPX2 protein expression level and MFS in GI tract cancers (HR: 3.25; 95% CI: 0.99–5.51), and there was no significant heterogeneity across studies (I 2 = 0.0%, P Q = .697; fixed-effect model) (Fig. 3 ). 3.2.3 TPX2 over-expression and clinicopathological factors in GC There were only 3 studies [ 16 – 18 ] exploring the relationship between TPX2 level and clinicopathological features of GC. 3 studies were assessed the correlation between TPX2 expression and gender, lymph node metastasis (LNM) and tumor stage.

Discussion There is a strong trend towards increased use of PROMs in clinical studies of medical devices, most of which are conducted in the Western European region.

In addition, in the present study, protein intake showed a strong trend towards being inversely associated with eGFR in the linear regression analysis.

Expression analysis of the N 2 -fixation genes, nifA and nifH , demonstrated a strong trend towards higher expression in samples cultivated under 0.3 mM N when compared to the 3.0 mM N treatment, being significantly higher in this condition for nifW expression ( Figure 8 ).

After compensating ypT and ypN staging, there was a strong trend in DFS; however, there was no significant difference in DFS ( p = 0.056) and OS ( p = 0.528) between the <10 nodes group and the ≥10 nodes group ( Figure 2 ).

It is worth noting that although the reduction in 12-month mortality rate with PE in this study did not reach statistical significance ( P = 0.051), we observed a strong trend that the mortality rate in the PE group was lower than that in the non-PE group, this trend is consistent with the findings of some previous studies, for example, a meta-analysis of ANCA-associated vasculitis patients, which included 9 trials and 387 patients, showed that the use of PE was associated with a positive signal of reduced mortality [ 27 ].

A strong trend towards reduction in maternal mortality was also observed: RR 0.55; CI (0.26–1.14).

gondii antibodies in camels over 4 years of age ( Table 2 ), indicating a strong trend of increased seropositivity with advancing age.

The association of urban living with development of MUO is more robust, especially since there is a strong trend of odds across the range of exposure ( Table 4 ) and there is a previous suggestion of a link between urban living and development of MS in people [ 37 ].

Among other prognostic factors, smoking (HR = 1.48, P = 0.061) demonstrated borderline significance, representing a strong trend.

There was a strong trend (1.6% average absolute change per year) towards increased fractions of women undergoing additional PCI of non-IRA whereas a corresponding trend in male patients was only 0.3% per year.

55 , 56 Indeed, in Study CA204-009, a strong trend toward longer PFS was reported for patients homozygous for the high-affinity FcγRIIIa V allele ( Figure 4 ).

We observed a strong trend towards cellular enlargement in VSMC treatment with EC EVs (Online Figure IX-A), which neared the effect of the pro-hypertrophic molecule, angiotensin II [ 42 ].

Although, no significant difference was found between the subgroups in TTP (54.3 vs 88.1 months, P = 0.149), the data showed a strong trend that patients with a high mGPS suffered an early progression in about 2.8 years.

route one month later showed significantly lower anti-OVA immunoglobulin (Ig) A titres and a strong trend towards lower anti-OVA IgM, IgG1, IgG2 and IgG titres relative to the i.p. control group indicating induction of oral tolerance [ 27 ].

There was a strong trend of improved survival among patients who received surgery. 4.

In patients with ER-negative breast cancer receiving chemotherapy, patients with increased CCR5 populations showed a strong trend toward reduced metastasis-free and relapse-free survival compared with the patient population showing reduced CCR5 expression in their tumors [ 9 ].

MCTI default values had a strong trend of overestimation, with an average of 60.3% for both genera, except for the youngest individuals (7.3–10 years) of Pinus spp. for which there was a slight underestimation.

Interestingly, we detected a strong trend indicating that high MC counts correlate with splenomegaly (Fig. 5D ).

Furthermore, in the genus Staphylococcus , we observed a strong trend of a decreasing r/m with increasing distance from Ori and hotspots of r/m proximal to Ori, and this had been observed in two prior studies in S. aureus ( 6 , 7 ).

Introduction In recent years, a strong trend has developed in favour of natural dietary supplements and herbal remedies due to the growing scientific evidence confirming the health benefits of extracts and bioactive compounds isolated from plants.

Expression of the inhibitory molecule PD-L2, on the other hand, was not as strongly affected and was significantly upregulated only by HAdV-B7, -B34, -C1, and -D26, whereas the expression showed a strong trend toward a decrease after transduction with other HAdV types such as HAdV-A18, -B21, -B50, -D17 and -D74.

These plots show a strong trend where our model resulted in greater predictions closer to the periphery of the Great Basin.

EVs and EVs-Associated mRNAs Diagnostic Potential in Diabetes and Its Complications DM is the most relevant metabolic disorder, affecting about 100 million persons worldwide, with a strong trend to increase.

Also, neither mean interstitial glucose (6.00 vs 6.03 mmol/L; p=0.865) nor HbA1c (5.40% vs 5.63%; p=0.052) differed significantly between participants with and without CAN, although HbA1c showed a strong trend toward higher values in the neuropathy group.