OS between the two group showed a strong tendency towards statistical significance ( P =0.05), which is consistent with other reports [ 19 , 21 , 22 ].
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However, none of these relationships was significant, except Australia, which showed a strong tendency towards statistical significance (z2 = 3.82; p = 0.0506).
In addition, a strong tendency towards statistical significance ( P = 0.051, Table 1 ) has been found between PTPN12 expression and the serum AFP levels.
In patients with laryngeal squamous cell carcinoma (LSCC), high expression of IL-33 in tumor samples was an unfavorable prognostic factor, with a strong tendency towards statistical significance (p = 0.051) ( Figure 3B ).
Interestingly, we detected a strong tendency towards statistical significance ( p = 0.051) regarding the correlation with circKEAP1 expression and CD8 + T-cell density (Figure S8 B).
ypT0-2: HR, 2.02; 95%CI, 1.14–3.58; p = 0.016), while AC treatment had a strong tendency towards statistical significance (AC vs. non-AC: HR, 0.56; 95%CI, 0.31–1.00; p = 0.051), followed by mucinous/signet-ring cells (HR, 1.68; 95%CI, 0.94–3.03; p = 0.081), SAE (HR, 1.68; 95%CI, 0.93–3.02; p = 0.086), and LVI (HR, 2.06; 95%CI, 0.90–4.72; p = 0.087) with marginal significance ( Table 3 ).
A strong tendency towards statistical significance ( p = 0.051) was observed in rs539689 allele distribution between patients and controls in overall study subjects.
However, it cannot be excluded that the observed sex-specific associations may result from a small group of the studied men, especially as in the recessive model, a strong tendency towards statistical significance was observed in men ( p = 0.052).
The difference in showing tumors before reconstruction was a strong tendency towards statistical significance ( p = 0.052), while the difference after reconstruction was not significant.
The results of Cox regression showed that cirrhosis ( P = 0.018) and NRF1 expression ( P = 0.004) correlated with survival of LIHC, and the TNM stage showed a strong tendency towards statistical significance ( P = 0.052).
Coexistence and Associated Daily Activity Rhythms There was a strong tendency towards statistical significance in the daily activity pattern in red serows when they were on their own and when with Chinese serows ( p = 0.052) ( Table 6 ) with lower overlap in activity pattern (mean Δ 1 = 0.599; CI: 0.427–0.822) ( Figure 6 A).
Correspondingly, DFS of patients with CNV amplification (n=43) was much lower compared to the ones without CNV amplification (n=98), with a strong tendency towards statistical significance (Chisq=3.7, P=0.053) (Figure 2 B).
Moreover, we observed a strong tendency towards statistical significance for normal hypothalamic-pituitary-thyroid-axis function at diagnosis in good-response to SRLs group (p=0.054).
The high stable trajectory of LVM/BSA had a strong tendency towards statistical significance related to all‐cause mortality in CKD (HR, 2.19 [95% CI, 0.98–4.89]; P =0.054) or non‐CKD individuals (HR, 1.79 [95% CI, 1.00–3.21]; P =0.050; Table 6 ).
An unexpected finding of this study was that none of the patients in the screw group experienced end-of-stem pain, whereas five knees in the non-screw group reported mild tibial end-of-stem pain; the incidence of end-of-stem pain in the screw group was less than that in the non-screw group, with a strong tendency towards statistical significance (0/55 vs. 5/51, P = 0.0548).
But in multivariate analyses, colonization of Pg was a favorable prognostic factor, with a strong tendency towards statistical significance (HR 0.340, 95% CI 0.112–1.025, P = 0.055) [ 10 ].
Indeed, following a strong tendency towards statistical significance, patients harbouring tumours with the E-cad loss /S100P ret molecular phenotype exhibited the worst survival of the cohort ( p = 0.055; Fig. 4 d).
In addition, patients who died had a significantly lower incidence of angiographic success, a higher rSS and more multivessel disease (Table 2 ). CA125 when evaluated as a continuous variable showed a strong tendency towards statistical significance for mortality (9.2 [6.4–14.5] vs. 8.0 [5.5–11.2], p = 0.056).
Longitudinally, increased PP was associated with worse memory performance with a strong tendency towards statistical significance (β = -1.829*e -2 , P = .058, Figure 2C ).
Smoking and family income at baseline showed both a strong tendency towards statistical significance (p=0.06) ( table 5 ).
In our analysis there was a strong tendency towards statistical significance for increased bone density in the metastases with concomitant bisphosphonate treatment 3 months following RT (p = .069) and after 6 months the mean increase in mean bone density was still larger in patients receiving combination treatment compared to those without bisphosphonates (245.8 HU ± SD 151.5 vs. 171.9 HU ± SD 114.4).
Multivariate analysis revealed that a strong tendency towards statistical significance was found between PD-L1 expression and poor OS (P = 0.081).
Discussion Previously, we found that rs733618 of CTLA4 was significantly associated with GO and rs16840252 had a strong tendency towards statistical significance based on the data from 22 GO cases and 20 healthy controls [ 20 ].
Although this result was not significant, it showed a strong tendency towards statistical significance.
The analysis, although indirectly—as it was based on the type of procedure—showed a strong tendency towards statistical significance and a substantial effect size, indicating that over 20% of the variability in microbial composition could be explained by the factor studied.