Malignancy showed a statistical trend (0.05 < p < 0.15).
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“a statistical trend”
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p=0.09
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A statistical trend was defined as p < 0.15.
Variables that showed a statistical trend ( p < 0.150) in the univariate analysis were considered in multivariate analysis to identify independent predictors of response.
Additional covariates were selected using a four-step process: 1) identification of cross-sectional and longitudinal patterns in the data, 2) identification of variables which were predictors of outcome based on a statistical trend defined as a P < 0.15, 3) selection of variables that were significant independent predictors of outcome, with a P < 0.15 tolerance, and 4) assessment of the clinical relevance of the identified variables by an independent scientific advisory committee.
Parameters considered as potential predictors were those showing a statistical trend ( p < 0.150) in univariate analysis and the parsimonious model was derived using backwards variable selection at a p < 0.05 level. 3.
Many of those miRNAs (10–15% of the total miRNAs reported on) showed a statistical trend in the data regarding a difference in miRNA expression between the zinc group and the placebo group ( P < 0.15).
Second, bivariate analyses were used to identify variables which were predictors of outcome based on a statistical trend defined as a P < 0.15.
To identify factors independently associated with ORT formation, a two-step approach was followed where potential predictors were first identified based on whether they showed a statistical trend ( P < 0.15) in univariate analysis, as described above.
(2) A general decline of suicide rates from 1975 to 2016 (1975–1988, SMR: 7.05, CI: 2.24–17.00; 1989–2002, SMR: 3.12, CI: 1.91–4.48; 2003–2016, SMR: 1.95, CI: 1.45–2.57), though a statistical trend was not found ( P = 0.173).
Upregulation of mir-29a-5p and downregulation of mir-187-3p in stressed animals indicated by sequencing was confirmed by qPCR (two-tailed one sample t-tests, mir-29a-5p: t (11) = 4.207, p = 0.0015; mir-187-3p: t (11) = 3.751, p = 0.0032) and the other two miRNAs, mir-199a-5p and mir-135b-3p, showed a statistical trend in the expected direction based on the sequencing results (two-tailed one sample t-tests- mir-199a-5p: t (11) = 1.457, p = 0.1732; mir-135b-3p: t (10) = 1.623, p = 0.1357).
However post hoc analysis ( Fig 4C ) revealed that the PDGF-BB treated cells remained a statistical trend (p = 0.18).
A statistically increased astrocytoma incidence was reported at 7.5 mg/mL MTBE (calculated dose: ∼333 mg/kg-bw/day) when assessed using a statistical trend test (Cochran), but not when using a pairwise comparison (Fisher’s exact test p < 0.181).
In another study that evaluated immunotherapy in a group of 87 patients, those with the Gly12Asp variant had a higher probability of a therapeutic response (OR (95% CI) = 0.31 (0.09–0.95), p < 0.05) and a statistical trend toward improved survival (HR (95% CI) = 0.53 (0.21–1.36), p = 0.185) [ 22 ]. 4.3.
4.5 ± 2.0 p = 0.026); other factors showing an association at the level of a statistical trend were low BW ( p = 0.191) and the coexistence of IVH ( p = 0.142).
Additional analyses were completed to compare the 6-min walk distance at baseline between the dropout and completed groups; findings demonstrate a statistical trend with a 35 m higher 6-min walk distance ( p = 0.196, Cohen’s d = 0.76, 95% CI − 17 to 83 m) performed by the dropout group (302 ± 84 m) compared to the completed group (269 ± 78 m) at baseline.
A statistical trend was considered for P < 0.20.
However, when data were plotted, a statistical trend (P = 0.20) was observed for PDGF-BB concentrations in P-PRG from SC in comparison with ACD-B (Figure 2 ).
To use the minimum number of animals necessary, we analyzed data once n=4~5 (or ~8 for the non-EEG/dialysis experiment) was reached, and the sample size was increased if a statistical trend (p<0.2) was observed.
For all univariate analysis, if multiple confounders show a statistical trend for an association (p>0.2) with a given outcome, a purposeful backwards and forwards stepwise analysis will be conducted to identify a subset of confounders that show significant associations with the outcomes.
On MVA ( Table 5 ), treatment time was not associated with FFBF or FFDM when included in a model with NCCN risk category, although there was a statistical trend ( p < 0.2) for treatment time.
First, exploratory analysis based on Spearman’s rank correlation was conducted to identify independent variables that show a statistical trend ( p < 0.2) of association with the outcome of interest.
Although the probability of observing grooming did not show a statistical trend across feeding states (ANOVA: p = 0.21), the duration of these grooming bouts did (ANOVA: p < 0.001).
While 2uM of sorafenib alone didn't affect viability, the addition of Metformin resulted in statistically significant reduction in viability of SK-Hep-1 (p=0.029), and a statistical trend in reduction of viability in PLC/PRF/5 and HuH-7 (p=0.23, p=0.059 respectively; Fig. 1 ).
On the multivariate level using parameters from the univariate analysis with a statistical trend of p < 0.25, no significant risk factors could be detected.
Whilst the predictor attention , p = 0.061 shows a statistical trend, the predictors phonemic category fluency (RWT P), p = 0.279, phonemic category flexibility (RWT HT), p = 0.266, semantic category fluency (RWT Animals), p = 0.086, semantic category flexibility (RWT Sport-Fruits), p = 0.338 as well as verbal intelligence , p = 0.270, and numerical intelligence , p = 0.330 had no significant effects on cognitive ToM performance.