Zuranolone 30‐ and 45‐mg doses did not produce significant next‐day effects on sleepiness or psychomotor performance; however, KSS results showed a slight trend towards increased signs of sleepiness at the post‐PSG assessment in the zuranolone 45‐mg group.
Despite also finding a slight trend in the same (negative) direction as our results and the cone snail study above [ 22 ], this was non-significant and explained very little of the data.
Specifically, Bgn HO and Dcn HO mice exhibited a slight trend toward higher ERK phosphorylation levels, which was completely abolished in Bgn HO/ Dcn HT mice (Fig. 7c ).
However, there was a slight trend toward detection with increased tumour size.
For representatives of Solobacterium (P = 0.054) and Fusobacterium (P = 0.065) a slight trend towards reduced abundance in samples derived from GC treated patients was observable, but is missing significance.
Meta-analysis of vitamin C studies found no significant difference in C-reactive protein concentrations (−0.50; 95% CI: −3.63, 2.63; I 2 = 0%), intensive care unit stay duration (pooled mean difference: 1.44; 95% CI: 0.07, 2.81; I 2 = 0%), or mortality (pooled odds ratio: 0.55; 95% CI: 0.28, 1.09; I 2 = 0%), with a slight trend favoring reduced hospitalization duration (pooled mean difference: −2.37; 95% CI: −2.99, −1.76; I 2 = 49%).
In this regard, the general weakening of the return-flow coincides with a slight trend in sea level air pressure (~−1 h P a / d e c a d e ) over the Svalbard shelf (Fig.
There was a slight trend of increasing plasma C max with decreasing age but was not exhibited of plasma AUC 0–t ( Figure 3 ).
The A313S allele showed a slight trend toward stronger suppression but did not show a significant improvement over the wild‐type SIRT6 when assessed for the 3′ bias.
Although their study suggested a slight trend toward greater dermal and subcutaneous thickness on the subcutaneous side, these differences did not reach statistical significance, likely due to the small sample size ( n = 6).
As follow-up continues, there is a slight trend towards escalating from csDMARD to bDMARD use.
There may be a slight trend towards better outcome in the contacts receiving IPT, although not significant.
However, a slight trend towards a higher degree of swelling in the GT group than in the NGT group was noted.
With this, the smartFilm tablets can be considered to yield comparable intestinal permeation values for curcumin to that of the micellar curcumin, with a slight trend towards a deeper permeation of curcumin.
In fact, GABARAPL1 SKO cells displayed a slight trend towards higher EGFR total protein levels over time, while a slight but significant (1.32-fold, p ≤ 0.05) increase in the basal total EGFR levels was observed for GABARAPL2 SKO cells.
Secondary analysis: Th1 cytokines and sustained IGRA conversion (binary outcomes) When assessing binary outcomes for sustained IGRA conversion, Th1 cytokine markers collectively showed a slight trend toward positive association, though confidence intervals for most pooled estimates crossed the null.
2 ▸ a ) does not change much over the course of the years; if anything, there is a slight trend that more carbohydrate residues have been built or rebuilt in recent years.
A slight trend in the norketamine model fit at the inhibitor phase can be attributed to the fast metabolism to secondary metabolites, but also to the marked between‐subject variability in the S ‐ketamine metabolism.
A slight trend toward increased inflammatory markers (CRP, IL-6, and the proportion of immature neutrophils) was observed in patients with higher CIRS-G scores, although differences did not reach statistical significance (Fig. 3 a-i).
Thus, the median RT-PCR positivity rate in symptomatic study populations was about 12 percentage points higher than in asymptomatic study populations, indicating a slight trend in the RT-PCR positivity rate with respect to the proportion of symptomatic subjects.
There was no significant effect of ALG/HAP scaffolds on COL10A1 expression, although a slight trend was noticeable.
Thus, though the patterns of risk are consistent with a possible risk due to HC exposure, the limited number of observed and expected deaths are only suggestive and do not allow a concise interpretation. Other relevant kidney cancer studies include a population-based case-control study among renal cell can- cer cases (31), in which a slight trend of increasing odds ratios was found for gas station attendants.
On the contrary, our study revealed the negative effect of mesenchymal PD-L1 expression on survival, which was in line with the findings of Shen et al.[ 26 ] who also demonstrated a slight trend for poorer overall survival in osteosarcoma patients with high PD-L1 expression.
With respect to the gut microbiome-related metabolites TMAO, betaine, and choline, the placebo-treated group had a small but statistically significant increase in TMAO in the fasting state ( p = 0.014) ( Table 3 ), whereas there was a slight trend for a reduction in TMAO in the participants whose diet was supplemented with blueberry powder in both the fasting and post-prandial states ( Table 3 and Table 4 ).
6 ), but a slight trend toward more downwardly tilted head postures seems to occur in species living in a more open habitat (Fig. 6 ); however, this trend is not significant (F = 1.343; p-value = 0.792).