“a slight trend”

Although it was not considered a study outcome a priori, we also identified a slight trend (i.e., not statistically significant) toward higher preoperative seropositivity of anti-Col-V (78.6% vs. 56.5%, p = 0.17), anti-Kα1T (50% vs. 43.5%, p = 0.69), or either SAb (78.6% vs. 65.2%, p = 0.39) among patients with a manometric diagnosis of IEM.

IMI group comparison ( p < 0.001), with a slight trend involving OS elevating FAAH expression ( p = 0.1720 for vehicle vs.

Mast Cell Density, Survival, and Occurrence of AE-IPF The correlation between the survival time and MC density was not statistically significant, although there was a slight trend towards a shorter survival and low MC density (319 MCs or less per square millimeter) (RR 1.59 95%CI 0.81 − 3.10, p = 0.175).

Although a slight trend in PT was observed among the rs6046 genotypes ( p = 0.179; Figure 1 B), this effect did not reach statistical significance.

However, among the subset of 109 participants who engaged in injection drug use, there was a slight trend toward increased HCV testing uptake among those who used A-CHESS (89% vs 85%; hazard ratio: 1.34; 95% CI 0.87-2.05; P =.18), and a stronger trend was observed when focusing on the subset of 32 participants who reported sharing injection equipment (87% vs 56%; hazard ratio: 2.92; 95% CI 0.959-8.86; P =.06).

The qRT-PCR data showed no alterations in Nfκb expression after 3 and 14 days (p > 0.05, Table 1 ), while a slight trend pointed towards an upregulation was noted at 7 days (p = 0.18, Fig. 4C ).

There was a slight trend in the same direction for median TTF in the low TS expression group to the high expression group (12.3 vs.11.7 mo, HR 0.82, 95% CI: 0.33 to 2.0, Log-rank p = 0.18) that did not reach statistical significance.

While there was a slight trend of lower 25(OH)D, and higher 1,25(OH) 2 D 3 concentrations with more amount of oil injected, the differences were not significant ( p = 0.18 and p = 0.76, respectively, Fig. 2 D and E).

While the following results are not statistically significant, analysis of randomly assigned upper size limits identified a slight trend of peak support at 40”, where the majority of participants displayed positive or neutral opinions ( P = 0.18, Fig 4b ).

In terms of medication history, there was a slight trend toward absence of archaea in patients with exposure to proton pump inhibitors (PPIs) (OR 0.52, p = .18; Table 1 ).

After 2 d of HFD, the expressions of Il-7 and Ebf-1, critical to early B-cell development, were down −20% ( P = 0.08) and −11% ( P = 0.06), while Pax-5 expression, a marker indicating an intermediate stage of development, showed only a slight trend in reduction relative to RD (−9%; p = 0.18).

Leptin levels were significantly higher in females ( p = 0.003) and, although a slight trend was observed, we found no effect due to age ( p = 0.182) ( Figure 5 A).

There was a slight trend towards more matrix staining (56 vs 36, p = 0.184) and better tissue morphology (36 vs 27, p = 0.151) in the CB group.

However, when we compare the patients with metastasis with the disease-free patients, we observe a slight trend to metastatic patients present higher VEGF expression (p=0.185).

In the group that got the "abnormal" results (the ambiguous result of MSI-H tumour with various immunohistochemistry results), men (n = 14) appeared to show a slight improvement in QOL, though not statistically significant (p = 0.53) while women (n = 13) showed a slight trend toward decrease in self-rated QOL (p = 0.19), but again, not statistically significant.

For every 0.1 increase in the deprivation index, there was a slight trend towards lower PDC (estimate 0.84, p =0.191) and higher gap days (estimate 1.19, p =0.189), but again, not statistically significant.

The therapeutic effect did not significantly differ across follow-up visits but showed a slight trend of diminishing over time (HFS: F (1.6, 15.55) = 1.82, P = 0.198; VFS: F (1.7, 17.37) = 1.44, P = 0.263; LFS: F (3, 30) = 0.86, P = 0.475).

There was a slight trend towards greater expression of topoisomerase‐1 in patients with UIP versus those with NSIP (61% vs 29%; P = 0.20), although the difference was not statistically significant.

There was a slight trend (p < 0.2), but no significant difference in median OS in patients with CD68 + cell density ≥median versus <median (22.6 vs 17.8 months; HR: 0.6; p = 0.173).

Proportion correct to true items was slightly lower in the Coordinate condition than in the Anomalous condition, F (1,23) = 3.14, 0.05 < p < 0.10, with a slight trend toward the increase being larger for atypical than for typical exemplars, F (1,23) = 2.84, 0.1 < p < 0.2.

While it appears there is a slight trend, with FUS alone potentially inducing a small amount of necrosis, there were no significant differences between the control groups (ANOVA, p = 0.200).

A slight trend to a higher score in the I/R group (1.13 ± 0.13; p = 0.200) compared to controls was also noted ( Figures 9I,J ). 4 Discussion 4.1 Medicinal Chemistry Our initial attempt to find new proprietary ATX-inhibitors was based on the seed compound PF-8380 ( 1 ) and relied on modifications of the molecule which are in essence: 1) the ZBG, 2) the core region, and 3) the structural element that fits into the lipophilic pocket ( Figure 1A ).

A slight trend towards higher 180-day mortality in urinary tract infections was not significant (p = 0.2).

Factors including no previous surgery (OR: 0.659, 95% CI: 0.364 to 1.190, P = 0.169), longer lesion time (OR: 1.57, 95% CI: 0.810 to 3.050, P = 0.181), and Kellegren–Lawrence grade 2 or less (OR: 0.584, 95% CI: 0.328 to 1.040, P = 0.068) showed a slight trend towards statistical significance ( P < 0.200).

We evaluated several clinical variables and their influence on CD8 + T-cell reconstitution, and none of them correlated significantly with faster CD8 + T-cell reconstitution at the time point of 28 days post-transplant, although there was a slight trend towards faster CD8 + T-cell recovery in patients with higher CD34 + -cell dose in the graft (P = 0.20).