Barely Significant
← all phrases

“a slight trend”

4,079 sentences · 4,079 papers · 4,917 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

The APTH (Ambulatory Blood Pressure and Treatment of Hypertension) trial in 1997, the THOP (Treatment of Hypertension Based on Home or Office Blood Pressure) trial in 2004, and the HOMERUS (Home versus Office MEasurements, Reduction of Unnecessary treatment Study) trial in 2007 failed to show any significant difference in surrogate endpoint outcomes, such as left ventricular mass changes, with a slight trend toward lower medication costs balanced by the higher costs of the ambulatory and home blood pressure equipment. 43 - 45 Moreover, the idea of developing an ideal trial for absolute evidence becomes a difficult task, as noted by the Agency for Healthcare Research and Quality (AHRQ), which has estimated that a sample size of 26 000 to 57 000 patients would be needed to achieve a 10% relative risk reduction in a 10-year trial comparing office versus ambulatory blood pressure monitoring. 46 Such a trial is unlikely to happen anytime soon.
Twenty-Four-Hour Ambulatory Blood Pressure Monitoring.
J Prim Care Community Health · 2020 · PMC7356999
Regarding a potential correlation between SEC62 expression and response to treatment according to RECIST 1.1 criteria, no significant difference in SEC62 levels was seen between patients with complete remission (CR), partial remission (PR), stable disease (SD), and progressive disease (PD), with only a slight trend towards lower SEC62 levels in CR patients compared to non-CR patients (PR + SD + PD; Figure 1 F).
Data analyzed by only maternal age showed no differences in the quality of day 3 embryos, a slight trend toward higher blastulation rates in younger patients compared with advanced maternal age, and no difference in the number of embryos biopsied.
When studies were ranked from high glucocorticoid resistance in patients to low glucocorticoid resistance using the “glucocorticoid resistance index,” there was a slight trend for studies that reported high glucocorticoid resistance in patients to produce larger effect sizes (based on 170 patients and 187 controls; Figure 4A ).
Response rates and overall survival were evaluated using pooled statistical analysis.The pooled response data in 2281 patients showed a slight trend favouring the combination therapy, although this did not reach statistical significance (odds ratio (OR), 0.79; 95% confidence interval (CI), 0.60–1.05; p =0.10).