“a significant trend”

Overall, there was a significant trend for increased cases in MAUDE over time ( P = .02 for linear trend; Figure 1 ).

Although studies staining for NKp46 also revealed a significant trend, the prognostic value was weaker 41 , 51 , 65 , 77 ( n = 4, HR=0.64, 95% CI: 0.41–1.00; p = 0.020) ( Fig. 5 B).

In the male groups, aged from 0 to 19 years and from 20 to 29 years, a significant trend occurred in the increase of incidence rates, with an increase of 0.159 and 0.606, respectively, of the rate (p = 0.02) per year.

Results: We found a significant trend of decreasing RRs for brain cancer with longer duration of allergy/atopy ( P =0.02), but not for other conditions studied.

Although there was a significant trend ( P = 0.02) in the association between the beverage pattern and advanced AMD, the significance seemed to be due to a random variation ( Supplementary Fig.

reported micronutrient status in 99 critically ill children with organ dysfunction, including respiratory failure, and compared it with 102 healthy controls; the results showed a significant trend ( p < 0.02) toward a plasma level decrease in six micronutrients (selenium, zinc, cooper, vitamin E, vitamin C, and β-carotene), while oxidative stress increased.

Combined effect between CD14 rs2569190 and delivery mode has a significant trend P-value (P = 0.02).

While TDR remained stable throughout the study period, clinically relevant resistance to first line drugs showed a significant trend to a decline (p = 0.02).

Additionally, death as an outcome also demonstrated a significant trend in favor of DOAC monotherapy (RR = 1.33 [1.05, 1.68]; p = 0.02; I 2 = 19%). 4 Discussion In this extensive meta -analysis comprising more than 50 000 patients, DOAC monotherapy significantly reduced the risk for major bleeding compared with combination therapy with DOAC and ASA.

Moreover, there was a significant trend of birds molting during the non-normal months between 2000 and 2006 ( Fig. 2 , trend, p = 0.02), whereas no trend existed before 2000.

Additionally, there was a significant trend indicating that patients with higher tumor grades were more likely to be SEPT9(+) (p = 0.02) and PAI-1(+) (p < 0.01).

Notwithstanding the small number of cases (10 HD-MTX and 10 IT-chemo), we observed a significant trend in improved survival in the HD-MTX group compared to IT-chemo only group (median OS: 28 months in IT-chemo and unreached in HD-MTX; p = 0.02; Fig. 4 D). 5.

In Jakarta, HPV positivity was inversely associated with daily income when women having ⩾US $3 per day were compared with those with ⩽US $1 per day (OR 0.51, 95% CI 0.28–0.92, with a significant trend of P =0.02), while having had more than one partner was associated with a higher HPV positivity than one partner (OR 2.66, 95% CI 1.64–4.33).

After the intervention, a significant trend change occurred, with a monthly difference estimated at -0.4% (95% CI -0.7% to -0.1%, p = 0.02) resulting in a stable proportion of unnecessarily repeated HBs antigen tests.

While this was not the case for all conditions, there is a significant trend where a slower WT strain growth in a condition is associated with a larger number of strain‐specific knockout phenotypes (Fig 3 C, Pearson's r = −0.21, P = 0.02).

After adjusting for covariates, there was a significant trend ( p = .02) indicating higher odds of poorer sleep quality with increasing MIS quartiles, with Model 2 showing the strongest association.

Although a likelihood ratio test suggested no significant multiplicative interaction between miR-16 and miR-21 (p>0.05), there was a significant trend for increased risk of being classified as SGA from having only miR-21 reduced or only miR-16 reduced in expression to having both reduced in expression (p<0.02).

When dividing IgM anti-PC levels into quartiles, there was a significant trend across the quartiles for the presence of multi-vessel disease with decreased levels of IgM anti-PC (p = 0.02), identifying a threshold for IgM anti-PC at the 25 percentiles, 24.6 U/ml, thus IgM anti-PC were divided into high and low levels at the 25 percentiles.

A significant trend was found for larger mean divergence in VAS and WOMAC pain with increasing KL grade ( P = 0.02), indicating that the more pronounced the structural knee OA damage becomes, the more VAS pain and WOMAC pain scales differ in the outcome they are measuring.

A significant trend was also observed in boys ( p = 0.02) and in girls ( p = 0.04), respectively (Table 2 and Fig. 2 ).

Brewster et al (2001) reported no significant differences in stage among socioeconomic groups, but a reanalysis of their tabular data on tumour size in breast cancer patients shows a significant trend of increasing size with deprivation ( χ =5.17, 1 degree of freedom, P =0.02).

There was a significant trend of elevated expression of proteins ( n = 13) in the haemolymph of early diapause queens (binomial test, p = 0.02).

However, there was a significant trend effect of examiner ( F [3,34.63] = 3.6, p = 0.02) with lower respiratory frequencies in participants treated by examiner 3 compared to examiner 1 and 2 ( p < 0.05; examiner 1: 0.21 ± 0.07; examiner 2: 0.22 ± 0.07; examiner 3: 0.12 ± 0.03; examiner 4: 0.25 ± 0.04). 4.

Using data on employment history, females showed a higher risk of moderate–severe asthma associated both with higher monthly number of night shifts (OR 1.39 (95% CI 1.04–1.88) for >10 night shifts per month; model 2, supplementary table 6 ) and with higher lifetime duration of night shifts (OR 1.28 (95% CI 1.03–1.59) for >10 years of night shifts; model 2, supplementary table 7 ), but a significant trend was found only among females for lifetime duration (p=0.02).

After further adjustment for weight and height (model 2), knee extensor strength was significantly decreased in the highest versus lowest HbA 1c quartile (−4.70 ± 2.30 N · m) with a significant trend of lower knee extensor strength across higher HbA 1c quartiles ( P = 0.02).