“a significant trend”

Figure 1 shows a significant trend toward lower accuracy on this measure as DTN performance declined ( P =0.002).

However, when the data from the 3 visits were combined and corrected for repeated measurements, there was a significant trend toward higher levels of CRP in affected individuals ( P = 0.002 versus unaffected).

The quartile analysis of SHBG demonstrated a dose-response relationship (Q4 vs Q1 in model 3: OR = 0.61, P = .008), with a significant trend test ( P ≤ .002).

There was a significant trend with trial commencement year for the measures physical activity ( p = 0.002) and weight/BMI ( p = 0.000) and all symptoms, except for appetite loss ( p = 0.115) and pain ( p = 0.433).

There was also a significant trend in reducing plasma TAG (-50%) in G (Ala12) carriers as the PUFA:SFA ratio increased from 0.34 to 0.65 ( p = 0.002).

We observed a significant trend toward longer fragments after enrichment for all experiments (Fig. 5 , Additional file 3 : Figure S2) (paired samples t-test , p -value = 0.002), consistent with previous findings [ 8 , 17 , 41 ].

A significant trend change was detected in the Diabetes group ( P = 0.002), and the trajectory of 5-Year MACE Survival changed from a negative slope to a positive slope.

There was a significant trend towards fewer HALS and laparoscopic surgery procedures than laparotomy (P=0.002).

A likelihood ratio test of the reduced model against the null model revealed a significant trend of decreasing entropy (linear mixed-effect: χ 2 (1) = 9.45, P = 0.002).

There was a significant trend of increasing HPV viral load with increasing severity of cytological abnormality both when restricting the analysis to HC2 positives (p = 0.002) and when including all samples (p < 0.0001).

In survival analysis, there was a significant trend in local recurrence from groups A to C (p = 0.002, log-rank test for trend) ( Fig. 3B ).

Among the participants, 816(60.13%) reported experiencing chronic pain, with a significant trend showing higher rates of chronic pain across increasing VAI quartiles ( P = 0.002).

Trends in comorbidity and injury severity There was a significant trend towards increasing comorbidity level, with the average CCI increasing from 4.6 to 4.8 during the study period (p = 0.002).

There was a significant trend ( p = 0.002) toward an increase in mean age each year, increasing by 4.4 years ( p = 0.008) over the course of the analysis.

Moreover, although the model adjusting for age, gender, ethnicity, and total energy intake suggested a significant trend between lifelong milk exposure and cataract extraction history ( p =0.002), none of the individual groups were significantly different from the high exposure group ( p > 0.01, Table 3 ).

Length of stay and in-hospital mortality There was a significant trend toward increasing ED LOS over the tertiles ( P = 0.002) (Table 5 ).

There was a significant trend that the longer the duration of ACEI/ARB, the higher log [Calc/BSA] ( P = 0.0022) with Jonckheere-Terpstra trend test.

CSF 14-3-3 levels showed a significant trend of being higher in patients who had a shorter duration from symptom onset to death ( R 2 = 0.71, F = 19.55, P = .0022; Supplementary Figure 1 ).

We observed a significant trend ( P =2.28 × 10 −3 , Figure 1 right panel) in that the strength of association of the individual SNPs with TSMC (measured by the regression coefficient) tended to be larger for those with larger reported odds ratio of association with breast cancer risk, but this trend was largely influenced by SNP rs11814448 in DNAJC1 ( P =0.37 when excluding SNP rs11814448).

The Cochran–Mantel–Haenszel trend chi-square test revealed a significant trend of decreasing MCI prevalence with increasing CDAI ( p = 0.0024). 3.2.

From that, we observed a significant trend (Cochran–Armitage test P value = 2.6 × 10 −3 ) whereby newly acquired genes appeared more frequent than ancestral genes in these regions ( Fig. 6A ).

There was a significant trend between ellipsoid zone appearance and ability to quantify AOSLO ( P = 0.0028).

Figure 2 shows Kaplan-Meier curves of the proportions of subjects remaining in sinus rhythm in the 3 groups, which revealed that there was a significant trend toward an increased risk of AF recurrence in the group with higher GRS (log-rank test; p=0.003).

When CMI was stratified into quartiles for group comparison, the results from Model 3, adjusted for covariates, revealed that, compared with the Q1 group, the OR for the Q4 group was 2.071 (95% CI: 1.019–4.210), with a significant trend ( P = 0.003).

Although the antihypertensive treatment with the use of 2800 IU daily was not effective, a significant trend of an inverse association between the achieved 25(OH)D concentration and systolic pressure was noted ( p = 0.003).