“a significant trend”

A significant trend was observed, wherein higher HAR levels were associated with an increased risk of MACE.

Dose-response analyses of data from five studies revealed a significant trend; current smokers who smoked higher amount of tobacco had a higher risk of CAP.

Only ∼20% were seen within 10 weeks of symptom onset and ∼50% within 4 weeks of referral, with a significant trend towards longer waiting times following referral for first appointments in more recent years.

Discussion This study observed that higher total OBS was correlated with a decreased level of SUA and decreased incidence of hyperuricemia, with a significant trend across OBS quartiles.

Beyond that, similar to European Union, the export trade also has a significant trend over time, whereas the import trade is not obvious.

However, the PRMT1 and ADMA signal, although they had a significant trend, they did not reach significance.

A significant trend across quartiles was observed (p for trend = 0.014). 3.6 Mediated analysis Table 3 summarizes the mediation of the VOCm–frailty association by oxidative-stress markers.

Only for factor V Leiden mutation did we observe a significant trend related to the risk of Perthes disease (odds ratio 2.9; 95% confidence intervals, 0.2–47.8).

2 Compared with Western countries, China shows a significant trend toward a younger onset of STAAD. 3 Data from the Sino-RAD registry indicates that the average age of aortic dissection patients in China is approximately 51 years old, 4 more than a decade younger than patients in Western countries. 5 This implies that STAAD primarily affects the working-age population, many of whom are at critical stages of their careers and bear significant family and economic responsibilities.

An early intervention onset requires an early detection of ASD, and a significant trend toward such an early detection has been reported ( Chawarska et al., 2007 ; Costanzo et al., 2015 ; Kleinman et al., 2008 ; Lord et al., 2006 ; Rice et al., 2012 ).

A significant trend was observed across the RC quartiles and poor functional outcomes ( p for trend <0.001).

A significant trend shift was observed in the distribution of NET procedures, with endovascular treatment for acute ischemic stroke that showed a dramatic increase in 5 years.

For all compounds, there was a significant trend between dose and increasing M-PQ angle (combined plot in Figure 3 , per compound plots in Excel Figure S3).

We have to note that co-evolution does not imply a particular substitution rate along evolution, but that both members of the same CTFP evolve at a similar rate (in fact, we did not observe a significant trend for CTFPs towards a preferential evolutionary rate).

Elevated plasma Ang-2 is independently linked to a higher mortality risk, with a significant trend noted from days 1 to 3, particularly among pediatric hematopoietic stem cell transplant patients, highlighting ongoing endothelial injury ( Table 2 ). 314 Fluctuations in Ang-2 levels over time show varying relationships depending on assessment dates, with serial evaluations failing to effectively distinguish ARDS from non-ARDS conditions, thus limiting the reliability of a single measurement for diagnostics.

Furthermore, TFP was positively correlated with OA occurrence across all models, with a significant trend observed ( P for trend = 0.018).

Introduction A significant trend in the modern food industry is the development of food supplements specifically designed to improve human health and well-being, reduce the incidence of certain diseases, and improve human performance.

There was a significant trend towards greater protection from peripheral neuropathy with increased dietary diversification (see Table 3 ).

Our finding that there is a significant trend of decreasing estimated glomerular filtration rate (eGFR) as the dipstick changes from negative through 3+ was similar to the findings of other studies [10] , [11] .

In T-ALL cases, a significant trend was found between the shortening of a patient's survival rate associated with the lowest to the highest miR-16 levels for both disease-free survival (DFS) and overall survival [ 82 ].

In the primary model, each 1-unit increase in CTI was associated with an HR of 1.59 (95% CI 0.99–2.55), and participants in the highest quartile had a higher risk than those in the lowest quartile (HR = 2.22, 95% CI 1.06–4.62), with a significant trend test (P for trend = 0.027), indicating that the direction of the association was consistent with that observed in CHARLS.

Furthermore, telerehabilitation has become a significant trend in research studies because of the COVID-19 pandemic, which is continuing to affect the world through the delta and the omicron variants, and other epidemics.

In the majority of the analyzed countries, the share of health spending in total government expenditure has risen since 2000, though a significant trend was evident only in a few countries, and the increase was rather small, allowing only Czechia to reach a level above the EU average [ 54 ].

Meta-analyses ( Garg et al , 1998 ; Coughlin et al , 2000 ) and certain case–control studies ( Weiss et al , 1982 ; Riman et al , 2002 ) also failed to find a significant trend with duration of use, although some found a positive association ( Risch, 1996 ) or suggested a positive trend ( Kaufman et al , 1989 ; Bosetti et al , 2001 ).

Trials such as the SOLIDARITY and RECOVERY are ongoing, and first results were announced in favour of therapy with dexamethasone with a significant trend showing greatest benefit among those patients requiring ventilation.