“a significant trend”

There was also a significant trend of increasing LC depth and greater LC horizontal curvature with increasing severity of glaucoma ( P Trend = 0.04 and 0.02, respectively).

Although a significant trend was not present, we speculated that a short duration of high fat intake could explain this observation.

21 In that study, female participants showed a significant trend toward higher TSH levels across incremental BMI classes, whereas in male participants, the opposite trend was observed for FT4 levels (i.e.

Our study observed a significant trend in the reduction of age at the time of the first cycle of cryopreservation in a large cohort over a 13-year period.

Moreover, we retrospectively found evidence that our protocol of sequential open challenges with all cultivars on the same day showed a significant trend of milder reactions with every following apple.

The ongoing advancements in biomedical research have led to a significant trend towards the miniaturization and integration of electrochemical sensors [ 44 ].

There was a significant trend in CEMP-1 over time, and this trend was different among the 2 groups: the REG group showed a statistically significant rising CEMP-1 trend (0.18 ng/ml a week p = 0.012), while the OFD had a trend that was significantly lower (-0.22 ng/ml a week compared to the REG group trend p = 0.023), the OFD group lost on average 0.05 ng/ml a week.

Alpha Diversity Analysis As shown in Figure 7 , according to the statistical analysis, sediment bacterial α-diversity index had a significant trend, and the variation tended to be consistent among the three sample sites.

12 The study showed a significant trend in terms of older age distribution (median 59.3 years) and utilization of matched unrelated donors (45.2%) in more recent times. 12 The study also showed decreasing rates of acute and chronic graft- versus -host disease, with recent rates of extensive chronic graft- versus -host disease at 23%.

There was a significant trend of increasing inflammatory biomarkers in the ESS patients.

In contrast, although the proportion of antacid use decreased, a significant trend in the proportion of enteral nutrition and prokinetic agent use was not observed among patients with CHD (Tables S3 and S4 ).

In order to conclude on the direction of a significant trend, the Somer’s D measure of association was calculated.

There was a significant trend toward lower serum potassium concentration with increasing duration of spironolactone treatment ( Fig. 4 ).

This change is compounded by the fact that the delivery of care in all medical specialties is changing, with a significant trend towards virtual and remote care, a trend that has also started in nephrology in some areas [ 25 ].

For categories of MVPA, there was a significant trend towards a low risk of overall dementia when higher levels of MVPA were achieved (HR trend 0.66 [95% CI 0.62 to 0.70].

However, fungicide ( R = −0.50, df = 8; P = 0.12) and adjuvant usage ( R = −0.37, df = 8; P = 0.26) do not show a significant trend using Spearman’s correlation and have remained relatively consistent ( Supplementary Figs.

Moreover, treatments were additive, with a significant trend for higher nitrite levels in groups receiving two (L-arginine+nor-NOHA) or three (L-arginine+nor-NOHA+BH4) compounds.

Even if the surrogacy of TRG and NAR for improved DFS has been validated in the CAO/ARO/AIO-04 trial [ 16 , 17 ] and a significant trend to higher tumor regression and low NAR score correlated with improved DFS and lower incidence of distant metastasis in the PRODIGE-23 trial [ 12 ], potential surrogacy of both parameters has not been broadly reported in recent trials ( Table 4 ) [ 10 , 13 , 14 ].

This reflects a significant trend of higher-adherence individuals being more activated in managing their health.

While post-treatment EEG abnormalities did not significantly differ between the groups, a significant trend toward improved EEG outcomes was observed in the intervention group.

Introduction Segmented mirror technology addresses the challenges of manufacturing, transporting, and installing single-piece mirrors, representing a significant trend in the development of large aperture telescopes [ 1 , 2 , 3 , 4 ].

Note that inhibitory effects (negative betas in the Figure 5 B, especially for −40 ms lag) sporadically observed for some cells did not constitute a significant trend in the population.

In addition, genes in the JCVI role categories "Unclassified" and "Protein synthesis" showed a significant trend of having low p -values in the Choleraesuis and Typhimurium branch tests for positive selection, respectively, as compared to genes in other role categories (Bonferroni corrected P = 0.002 and P = 0.013, respectively; one sided U-test).

According to the fully adjusted models, the adjusted odds ratios (95% CIs) for Q4 and Q5 were 0.70 (0.52–0.95) and 0.65 (0.47–0.90), respectively, which was supported by a significant trend ( p for trend = 0.017).

Introduction Minimally invasive surgery is a significant trend in surgical development.