“a significant trend”

Positive autocorrelation increases the probability of type I error, namely detecting a significant trend despite one not being present [ 61 ].

10 (d), it can be seen that the TCSP comprehensive score showed a significant trend of change under different combinations of ultrasound time and microwave time.

Additionally, a significant trend of reduced levels of bacteria-producing butyrate (such as Roseburia and Ruminococcaceae) has been revealed, correlated with lower butyrate levels in cachexia individuals and mice.

Although a significant trend was observed in MDS‐UPDRS part III scores over time, post hoc comparisons did not confirm significant differences at specific time points.

In the South region, there were 4 trends: from 1999 to 2006, the burden decreased but was then followed by an increasing trend from 2006 to 2023, with a significant trend from 2013 to 2021 with an APC of 20.6882 (95% CI: 19.6374–24.5342) that yielded an overall AAPC of 4.6558.

The ASDR for those aged 55 to 95 years has a significant trend with age, and the ASDR of both male and female reaches the highest at 95+ years.

We also reported a significant trend of decreased PFS and OS in ovarian cancer patients with a higher RSPO3 expression level, indicating that RSPO3 may serve as a novel prognostic factor in ovarian cancer.

The NOR and OPN groups showed a significant trend of clustering.

A significant trend is the incorporation and utilization of exercise in optimizing the care of PwP [ 9 , 102 ], and there are numerous PD-directed exercise programs/routines [ 10 , 87 , 88 , 90 , 103 , 104 , 105 , 106 ].

The Cochran - Armitage test indicated that a significant trend in the incidence rate of the cancers (Chi 2 = 559.85, P = < 0.001). 4.

According to the Third National Health and Nutrition Examination Survey, which included more than 15,000 people, there is a significant trend of increased mortality risk with increased number of nightly voiding episodes in men and women [ 5 ].

A significant trend has been noted in the increasing prevalence of cervical cancer in sub-Saharan Africa, Central America, and Southeast Asia.

By age group, a decline in influenza VE with time since vaccination was also observed only in patients ≥65 years, although interpretation is limited by small sample size, which likely precluded the observation of a significant trend with time since vaccination [ 37 ].

In the 14‐year monitoring period from 2007 and 2021, there was a significant trend toward an earlier onset of inflorescence emergence (Figure 2a ), flower anthesis (Figure 2b ), and seed release (Figure 2c ).

7 After 100 μM FAC treatment for 24 h, chondrocytes in the FAC group showed a significant trend of ferroptosis, an increase in catabolism, and a decrease in anabolism in chondrocytes. 2.5μM Quercetin pretreatment significantly increased the expression of anti-ferroptosis protein GPX4 (p = 0.0225) and increased the expression of SLC7A11 (p = 0.0884) in chondrocytes after FAC treatment.

Although there was a significant trend of increasing risk with numbers of affected relatives ( Table 1 ), there was no significant effect of family history (any vs none) of lung cancer in the study population overall or in late-onset cases, regardless of the age of affected relatives.

After treatment discontinuation a significant trend toward reversibility was also documented, with a progressive corneal epithelium and sub-basal nerve plexus regeneration.

The northern and southwestern regions exhibit a significant trend toward elevated extreme daytime and nighttime temperatures.

A significant trend in urinary CEMA levels with increasing ISO tar levels and Tneq was also observed.

The prevalence of ‘current asthma’ in children aged 6–7 years showed fluctuations (3.5%, 2.0%, 4.2%, and 0.6% in 1995, 2000, 2010, and 2022, respectively) without showing a significant trend.

APT-ICH patients showed a significant trend toward decreasing 1-year mortality throughout the study period (P for trend = 0.040).

Following HGF injection into the NP, a significant trend towards an increase in T2 signal intensity, type II collagen staining in the NP, and the number of BMP-2-positive cells in the AF was observed.

A significant trend was observed across the tertiles ( p for trend < 0.001).

This strategy is not only a current focal point but also represents a significant trend in future therapeutic developments ( Liu et al., 2014 ; Czechowicz et al., 2021 )​.

Discussion In this study, we demonstrate that there is a significant trend in established datasets towards reduced proportion of people having tests consistent with diabetes in ED but not in GP.