“a significant trend”

In recent years, cervical cancer miRNA research has shown a significant trend from the basic mechanism to clinical transformation.

3’UTR is also the main target of miRNAs and, interestingly, the distribution of the nucleotide sequences described in this study as having therapeutic potential for multitargeting also show a significant trend toward being more commonly located in the 3’UTR, with decreasing frequency approaching the 5’UTR (Fig. 3c ).

When competing for either the same MAT a or MAT α cells (except LH MAT α cells), although not all pairwise comparisons by t-test were significant due to the lack of contact when strains of no or low hyphal growth were involved, a significant trend by one-way ANOVA was observed that isolates with more hyphal growth yielded more double drug resistant colonies than isolates with reduced hyphal growth ( Fig 4C and S2 Table , seven group one-way ANOVA analyses are listed above pairwise Welch’s t-test analyses).

(2007) also reported that the risk of metabolic syndrome was highest in the third quartile and then plateaued in the case of DL-PCBs, whereas we found a significant trend for the association between the TEQ of DL-PCBs and metabolic syndrome.

Introducing telehealth into health insurance reimbursement has become a significant trend.

Although a significant trend was not observed, the highest quartile of total anthocyanidins and pelargonidin was significantly associated with reduced risk of adenocarcinoma compared with the lowest quartile.

Under the same rainfall duration, the content of photosynthetic pigments shows a significant trend of first increasing and then decreasing with the deepening of karst cracks.

2 , there was no evidence of a significant trend toward greater conductive hearing losses (CHL) at lower frequencies in ears with larger perforations. 3.2 Middle ear volume and conductive hearing loss The correlation of MEV to CHL was analyzed in perforated ears without evidence of cholesteatoma, while controlling for perforation size ( Fig. 3 ).

There was a significant trend to earlier smolt run initiation for two populations: Bush (−2.7 days/decade; 12 days over 1978–2020) and Burrishoole (−1.7 days/decade; 9 days from 1970 to 2022).

Chi-squared tests for trend were used to determine whether a significant trend existed within each neighborhood SES measure.

When stratified among KL groups, a significant trend was seen in the KL2 (p ​< ​0.025) Conclusion Our results suggest that decreased vitamin K intake from food may be associated with increased progression of knee OA.

Our results revealed a significant trend toward worse survival with increasing tumor size.

Within strata of risk factors, we observed no protection among lean women and a significant trend of increased risk with higher activity levels among obese premenopausal women.

Typhimurium isolation rate did not present a significant trend during the study period; however, its monophasic variant was identified in Greece for the first time in 2007 and, since then, has been among the five most frequently identified serotypes.

With the rapid advancement of artificial intelligence (AI), intelligent-assisted diagnosis and treatment in TCM have become a significant trend in the medical field [ 1 , 3 ].

Our regression analysis did not show a significant trend favouring KT with regards to mortality, SSC or PJI rate.

A significant trend was observed for a lower prevalence ratio (PR) of metabolic syndrome in individuals with high concentrations of adipose tissue ALA, compared to individuals with low adipose tissue ALA.

sPD-L1 demonstrated a significant trend with increasing severity and showed superior performance to conventional markers in distinguishing patients with organ dysfunction.

Cox regression analysis including interaction terms for age and log NT-proBNP showed that there was a significant trend for HR for all-cause mortality according to the interaction terms in the unadjusted model (p for interaction = 0.01), but not significant in the fully adjusted model (p for interaction = 0.33) (S-Table 5 ).

Results A significant trend of increasing ACDs with more contraction furrows were observed.

When applied to a xenograft model, however, the hypotensive activity of the drug prevented administration of statistically effective doses, though a significant trend toward tumor inhibition is observed ( Fig. 2 ).

A significant trend towards death away from home was most evident for CCCs (Fig. 2 and Additional file 3 : Table S2); despite yearly fluctuations, the last 10 years showed a stabilisation of HDs around 10% for CCCs, and 11% for OMCs and trauma.

A significant trend towards higher body mass index and more prevalent hypercholesterolemia, hypertension, and diabetes was found over time.

In recent years, the eutrophication of Caohai Lake has intensified, presenting a significant trend to an algae-type “muddy-water state” in some areas.

A significant trend for higher risks for all-cause deaths and cardiovascular deaths were found in the lower quartiles among hypertensive participants[ 25 ].