In the Cox proportional hazards regression analysis (reference: unimpaired cognition without IADL limitations), the HRs (95% CIs) of unimpaired cognition with IADL limitations, MCI without IADL limitations, and MCI with IADL limitations were 1.53 (0.90–2.61), 1.87 (1.28–2.74), and 2.88 (1.65–5.03), respectively, in the full-adjusted model (adjusted model 2), and a significant trend was observed in HRs between the four groups ( P < 0.001, Table 3 ).
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Further, the number of sickle-shaped blood vessels was associated with distant metastasis and OS, with a significant trend toward a poor prognosis (metastasis P < 0.001, Cox; OS P < 0.001, Cox) observed for patients with more than 100 such vessels in large maximal tumor sections.
Compared with controls, mean IGFBP-2 SDS were significantly elevated in patients with Dukes B ( P < 0.001), Dukes C ( n = 13 P < 0.001) and advanced disease ( n = 42 P < 0.0001), with a significant trend from early to advanced disease (one-way ANOVA P < 0.001).
A significant trend of increase in BMI was found in both sexes between 2011 and 2020( P < 0.001).
SCAT-A scores also showed a significant trend toward lower scores with longer years of competition [the shortest group: 20.5 (4.2), the longest group: 18.5 (4.3), p < 0.001 for trend].
We found a significant trend for both crows individually [crow 1: L (4) = 1722.5, P < 0.001; crow 2: L (4) = 1334.5, P < 0.001, Page’s trend test].
There has been a significant trend for increasing number of loci per year (R 2 = 0.07, p <0.001) as well as a weak increase in genetic diversity with year (H O : R 2 = 0. 0.009, p <0.001 and MNA: R 2 = 0.001, p = 0.003).
For WC-defined phenotypes, both obesity and metabolic dysfunction independently contributed to increased CVD risk relative to MHN: MHO (RR 1.84, 95% CI: 1.23–2.77), MUN (RR 1.58, 95% CI: 1.14–2.20), and MUO (RR 2.22, 95% CI: 1.63–3.04), with a significant trend across categories ( P < 0.001).
Furthermore, a significant trend ( P < 0.001) was observed, indicating an increased risk of hyperuricemia with higher quartiles of VFMI.
Interrupted time-series analysis did not detect an immediate shift in Medi-Cal or uninsured visits at the quarter of unwinding, but indicated a significant trend change, showing a decline of 0.37 pp per quarter ( P < .001) in Medi-Cal visits and an increase of 0.16 pp per quarter ( P < .001) in uninsured visits relative to the pre-unwinding period ( Table 1 , Figure 1 ).
Results There was a significant trend favoring DDKT as ADI quartile increased (Q1=59.1%, Q4=83.5%, P = 0.001).
When stratified by RFM tertiles, a significant trend was observed, with higher RFM tertiles being more prevalent among participants with asthma ( P < 0.001).
There was a significant trend (Spearman’s ρ = -0.66, N = 33, P<0.001) for villages with lower kdr frequencies in 2017 to show a higher increase over subsequent years ( Fig 3 ).
Taking prostate volume into consideration, there was a significant trend in increased detection of csPCa with decreased prostate volume by all methods ( Figure 4 , all P < 0.001).
While no specific trend for muscle power was observed in the HA group ( P =0.454) and the HA + 2 ESWT group ( P =0.217), the HA + 1 ESWT group exhibited a significant trend of muscle power improvement from baseline to 12 months after Day 1 ( P <0.001) (Fig. 4 ).
There was a significant trend in the association between duration of hypertension and VaD ( p < 0.001).
A significant trend for decrease in TSH values was determined ( p < 0.001), estimating a mean decrease around 0.034 units per month of follow-up.
There was a significant trend in OR over the four quartiles ( P < 0.001).
Statistical significance was set at p < 0.05, where 0.05 ≤ p < 0.1 indicates a significant trend, and p < 0.001 indicates a highly significant difference. 3.
066), and a post hoc linear contrast showed a significant trend ( F (1,94) = −6.02, β = −3.33, p < .001), indicating that there was a linear relationship among the corrected recognition scores to novel picture categories.
LV and RV volumes, function and LV mass (age-related differences) All LV and RV volumes showed significant differences between age groups with a significant trend for an age-depended decline (all p < 0.001).
There was no age trend in response in the usual postal arm ( P = .23), but a significant trend in the postal plus optional Internet arm ( P < .001), driven by the lower response rate in the 20-24 age group.
When age at the time of surgery was evaluated in 5 categories, a significant trend was noted, with increased frequency of CADP as the age at the time of surgery increased (chi-square test of trend, P < 0.001, Fig. 2 ).
When considering MRA use based on calendar year, there was a significant trend for increased MRA prescription at discharge among MRA‐eligible patients over time ( P <0.001) (Figure 2 ).
After adjusting for the effects of potential confounding factors such as age, sex, hypertension, duration of diabetes, biochemical data, and cataract status, a significant trend was observed for all contrast conditions ( p for trend p < 0.001).