“a significant trend”

A linear mixed-effects model revealed a significant trend ( P <.001) for improved SVMC already in the baseline phase.

For RCII, the association was stronger and more consistent: per SD increase (OR 1.23, 95% CI: 1.00–1.51, p = 0.046) and Q4 (OR 5.20, 95% CI: 2.24–12.08, p < 0.001) both showed significant independent associations, with a significant trend across quartiles ( p < 0.001).

Also, after 24 h exposure in the absence of metabolic activation, the frequency of binucleated cells with micronuclei was reported to be significantly elevated at all concentrations ( p < 0.05 for the lowest concentration tested; p < 0.001 all subsequent concentrations) with a significant trend test ( p < 0.001).

A significant trend was observed, indicating a higher in-hospital mortality with increasing normalized lactate load (quartile 4 vs. quartile 1: 62.7% vs. 24.2%, P < 0.001) as shown in Table 1 .

Additionally, compared to no use of tobacco nor vaping, exceeding the guidelines was significantly more common among men and women who only vape, who only smoke, or those who vape and smoke with a significant trend ( p < 0.001) for men.

A significant trend (P = 0.001) across eGFRcys categories was found, with an HR of 2.11 (95% CI 1.19–3.74) for eGFRcys <60 compared with eGFRcys >90 mL/min/1.73 m 2 .

In addition, the relation between professional titles and competency scores showed a significant trend with higher professional title ( P <0.001, Table 4 ).

A significant trend in the association between the degree of infertility (fertile, uRPL and UI) and the HSCORE level (negative, medium and high) was found ( P < 0.001; x 2 for trend).

Treatment with slowly eliminated antimalarials was associated with a significant trend to decreasing risk of P. vivax infection recurrence up to 63 days after both malaria due to P. falciparum monoinfection and malaria due to mixed infection ( P < .001 for trend in both cases; Figure 2 ).

We found a significant trend for both crows individually [crow 1: L (4) = 1722.5, P < 0.001; crow 2: L (4) = 1334.5, P < 0.001, Page’s trend test].

There was a significant trend of declining 1-year mortality with time, with high values of 17 patients (85%) observed in 1991–2000 to just one patient (8%) in 2011–2020 ( p < 0.001, Figure 2 A).

This association was rather slightly intensified after adjusting for age and sex, and other possible confounders, and a significant trend ( P < 0.001) was maintained.

The Jonckheere-Terpstra test showed a significant trend across 4 pain response categories in patients with PBMs and those with PNTs ( P < .001 for both).

There was a significant trend for with increasing race distance ( p < 0.001) with both failure to finish and pulled-up.

The association between AI across quartiles and diabetes incidence Table 2 explored the incidence of diabetes across AI quartiles, revealing a significant trend of increasing incidence with higher quartiles ( P < 0.001).

A significant trend towards higher stage prevalence with advancing age was observed (Kruskal–Wallis H = 22.46, p < 0.001).

The ES-J also differentiated healthy respondents (i.e., those with no history of MDE and without psychological distress) from subjects with a history of MDE and moderate to severe symptoms of psychological distress ( p < 0.001). The Jonckheere trend test revealed a significant trend ( p < 0.001): a healthy population without history scored higher on ES-J, and a severely distressed population with history scored lower on ES-J.

Comparing the ALS‐IPS with clinically derived stages based on the King's College system in all ALS subjects reveals a significant trend ( p = 0.001) of higher ALS‐IPS in progressive King's College stages (Figure 3B ).

Compared with controls, mean IGFBP-2 SDS were significantly elevated in patients with Dukes B ( P < 0.001), Dukes C ( n = 13 P < 0.001) and advanced disease ( n = 42 P < 0.0001), with a significant trend from early to advanced disease (one-way ANOVA P < 0.001).

The prevalence of metabolic vitamin B12 deficiency [Fedosov’s wellness quotient ω < −0.5] in our cross-sectional survey, within the three age groups 60–69, 70–79 and ≥80 year were significantly different and showed a significant trend (p < 0.001 for both) as follows: 8.0 % (37/426), 13.4 % (55/356) and 19.0 % (35/149).

Analysis of TyG-WHtR quartiles showed a significant trend in Q4 compared to Q1 (trend p < 0.001).

After full adjustment (model 3), FLI ≥ 60 was significantly associated with higher risks of all-cause (HR; 1.33, 95% CI; 1.26–1.44) and CVD mortality (HR; 1.32, 95% CI; 1.12–1.56), with a significant trend across FLI ( p < 0.001).

This upward shift continued, with women comprising 37% of speakers (38/103) by 2024. By domain, plenary sessions showed a significant trend ( P < 0.001).

Meanwhile, targeting VEGFR drugs had a significant trend of decreasing PDR compared with the control arms (OR 0.45, 95% CI (0.34, 0.59), P < 0.001, Figure 5 ).

A significant trend was observed in the fully adjusted model ( P < 0.001).