Indeed, we detected a significant trend towards longer GC tracts, most notably in PMS2-deficient cells, which confirms that MMR affects resolution of the heteroduplex intermediates arising during Ig GC ( 46 , 47 , 79 ).
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In the literature
A recent meta-analysis of cohort and case–control data on soy intake and breast cancer showed soy to be associated with a small reduction in risk ( Trock et al ., 2006 ) whereas another found a significant trend of reduced breast cancer risk with increasing soy food intake ( Wu et al ., 2008 ).
Increasing the load of the training protocol and improving adherence may reveal a significant trend towards higher MTLP after lateral training than after lifting training.
Our study demonstrated a significant trend of a decrease general physical activity, measured by the Yale score, from controls to DM groups, and a significant positive association between the Yale score and soleus muscle exercise SMBF.
The conclusions display a significant trend where Young’s modulus, bulk modulus, Poisson’s ratio, linear compressibility, and anisotropy parameters show an increase with increasing Si concentration.
Combining multiple imaging modalities to give full play to their respective advantages will be a significant trend in the future.
Disease-Free Survival According to the Beppu and RAS-Beppu Classifications The DFS curves of the three risk groups based on the Beppu and RAS -Beppu classifications were clearly separated, and there was a significant trend for shorter DFS as the risk increased ( Figure 2 ).
When grouped by decades of age, a significant trend was observed for miR‐199a‐5p and miR‐214‐3p (Figure 2B,C ; trend p ‐values 0.0384 and 0.0314, respectively).
A significant trend across quartiles was observed in all models (all P for trend < 0.0001), indicating a robust and consistent inverse association between PIV and Klotho levels.
In this sense, a significant trend was found in the fatality and mortality rates of COVID-19 with advanced age in humans, 40 given that there is a weakened immune system, underlying chronic diseases, multiple drug therapies, lack of attention and self-care, poor environmental hygiene, loneliness, and lack of adequate support fr
Precipitation declines significantly (−28 mm decade −1 ) in the A2 scenario, but does not have a significant trend in the B1 scenario.
Discussion Contemporary analyses of a homogeneous ethnic and socioeconomic group of children and adults at a single reference center in a low-middle income country over a fifteen-year period provide evidence for a significant trend per month of the ALL diagnosis, with the highest number of cases diagnosed in March, followed by October.
All three cohort studies reported stronger associations between PM 2.5 and cardiovascular mortality among obese subjects and one reported a significant trend of increased risk with increased body mass index.
The same tests in the longitudinal direction did not show a significant trend for different locations.
Even after further adjustment for nutrient intake in Model 3, the Q3 group remained significantly associated with reduced all-cause mortality (HR = 0.788, 95% CI: 0.657–0.944, p = 0.010), with a significant trend observed across quartiles (P for trend < 0.05).
We did not observe a significant trend of decrease in AML stem cell population in our limited sample size ( Figure 4A ).
HAMD scores differed between the PSA, nPSA, and HCs groups and did not differ between the PSA and nPSA groups, but there was a significant trend.
We conducted a changepoint analysis to analyse this time trend series to see whether there was a significant trend change after 2018.
Although past studies have not found a relationship between education level and traditional medicine use [ 2 ], our study showed a significant trend towards highly educated women being less likely to use traditional medicine than those with no education, with a significant effect found for women with a secondary education (OR = 0.42).
When adropin was categorized into quartiles (Q1 ≤ 3.94 ng/mL; 3.94 < Q2 ≤ 5.20; 5.20 < Q3 ≤ 6.55; Q4 > 6.55), participants in the highest quartile (Q4) had significantly lower odds of DKD than those in Q1 across all models, and a significant trend was observed with increasing adropin levels (P for trend < 0.01) ( Table 2 ; Supplementary Figure 1A ).
Long-term changes in crop phenology (observer network western Germany) The PVTT from emergence to heading (PVTT heading ) calculated from the observations for western Germany showed similar trends, with a 15% smaller PVTT heading in the most recent years than before 1986, which did not show a significant trend (Fig. 2d ).
However, at the later time point, i.e., at 72 h of incubation, the potential differences were not statistically significant; thus, they do not represent a significant trend. 2.1.
There is a significant trend between GRS and the age of onset groups for T2DM in the total Case population and also by sex.
In Model 3, with full adjustment for all covariates, the negative associations between NHHR and FEV1 (β = −21, 95% CI: −34, −7.7) and FVC (β = −29, 95% CI: −43 to −15) persisted, with a significant trend.
Although our results show no difference in the LA booster EF between the pre-ApHCM and normal controls, there was a significant trend that LA booster EF in pre-ApHCM decreased.