“a significant trend”

16 , 17 With the increasing demand for miniaturization, high-sensing efficiency, wide applicability, and cost reduction, the integration of high-performance biosensing platforms with hydrogels has become a significant trend, which represents a class of promising functional materials consisting of three-dimensional (3D) network structures produced by physical or chemical cross-linking. 18 , 19 Hydrogels have been widely used as reliable biomaterials for the fabrication of medical devices and scaffold-based tissue engineering because of their unique properties.

Moreover, the present model has been previously validated and indicates a significant trend towards cost reductions and a decreased duration of sick leave following the specific incorporation of effective targeted therapies.

A significant trend was observed across the CMI quartiles (p for trend < 0.001) ( Table 2 ).

Compared with patients from the least deprived neighborhoods, patients from the most deprived neighborhoods (ADI quintile >80%) had a 60% higher likelihood of PJI (HR, 1.60; 95% CI, 1.12-2.13) with a significant trend with worsening ADI ( P value for trend <.01).

Similarly, the values for the c-lattice parameter, which range from 3.220 Å at 200 μs to 3.223 Å at 50 μs, do not show a significant trend.

That is, a significant trend toward decreasing rates of POUR with increasing BMI.

Introduction The increasing level of antimicrobial resistance (AMR) is a significant trend seen throughout the globe, and this phenomenon may affect general public health at all levels of healthcare [ 1 ].

Further investigation into the associations by subtypes of benign breast nodules showed that animal-based dietary patterns were positively associated with breast cystic nodules, with ORs (95% CI) of 1.44 (1.01–2.06) and 1.61 (1.12–2.32) for the third and fourth quartile groups, respectively, with a significant trend ( P -value for trend test = 0.007).

The results showed that rCol III exhibited a significant trend in total tube length, number of reticular pores, number of junctions and number of segments in this cell line compared to the control group ( Figure 4C–F ), which suggests that rCol III has a promotional effect on blood vessel formation.

Among men, a significant trend towards a higher abundance of GP21, GP28, GP31, GP32, GP33, GP34, and trigalactosylated, trisialylated, triantennary, and outer fucose glycans in relation to increasing categories of alcohol consumption was confirmed ( Supplementary Table S3A,B ).

The Jonckheere–Terpstra test revealed a significant trend in the data: as better illness perception was perceived, the median anxiety levels decreased both at baseline, J = 8490.5, z = −2.098, r = −0.13 ( Figure 4 A), and at follow-up, J = 20326, z = −3.651, r = −0.18 ( Figure 4 B).

Although a reduction was observed over time in terms of presence/absence, statistical analysis showed a partial effect for the intensity score, showing only a significant trend.

With regard to scalar surface wind speeds, an examination of annual anomalies revealed a significant trend towards greater surface wind speeds from 1998–2012 both on LBB and GBB, which in each area was associated with increasing surface wind speeds across years both on and off the sandbanks.

Age‐subdivided management pathways in chest pain presentations Typical Chest Pain Analysis of management pathways for typical chest pain patients revealed a significant trend with age.

Historically, 9 out of 34 stations (26.47%) showed a significant trend.

24 , 25 , 26 Furthermore, with strong national policies supporting the development of AI in healthcare, the future of clinical treatment is set to increasingly rely on AI‐assisted imaging diagnosis systems, marking a significant trend in medical advancement.

Interestingly, there is a significant trend for the 20S core complex to be more stable than the 19S regulatory complex in B-cells, monocytes, and NK cells, but a clear and significant opposite behavior is observed for hepatocytes.

In HIV, the mean values of ECR1 when estimated for AIDS and AIDS related syndromes, gave a significant trend.

In addition to the centrifugal spread of the disease, some epidemiologic studies also showed a significant trend of an increase in human AE incidence in some previously known foci, for example, in Switzerland ( 10 ).

This means that it shouldn’t have a significant trend or seasonality component.

Furthermore, there was a significant trend between increased tertiles of ODI and risk of hypertension (trend test: p = 0.016), although the significant association of tertile 2, compared to tertile 1, with hypertension disappeared with adjustment for all the potential confounding factors ( Table 3 ).

There was a significant trend between shorter duration after an episode and higher ACS risk.

However, a significant trend in terms of increasing strength values with increasing part density can be observed.

In our sample we found a significant trend of thinning in choroid of T2D patients, also observed in nDKD group.

As the mice aged, a significant trend towards decreased pTie2/Tie2 ratios was observed in mdx/utrn +/− mice compared to WT mice, which did correlate with the changes in Ang1/Ang2 ratios.