“a numerical trend”

Mepolizumab vs placebo was associated with a numerical trend for improved pre‐bronchodilator FEV 1 from baseline in all patients except those with fungal sensitization only, although this may be due to the small sample size (n = 51) for this group (Figure 1C ; Table S4 ).

Image: Summary/Conclusion: There was a numerical trend towards better CR and EFS for novel therapy compared to traditional chemotherapy for first salvage, however the outcomes were not statistically significant.

While we observed a numerical trend in 90-day survival of patients with Impella support, our study was not powered to detect a mortality difference.

Furthermore, within lysis time Q4 (2940 to 11 302 s), there was a numerical trend towards higher rates of cardiovascular events with increasing lysis time on adjusted analysis ( Figure 3 ) that was consistent with previous findings in ACS patients and warrants future scrutiny of those with very high lysis times.

This implies a numerical trend rather than a statistically confirmed association.

In comparison with medical therapy, RFA showed a numerical trend that remained far from statistical significance (HR, 0.89; 95% CI: 0.62 to 1.27).

A numerical trend in favor of NVA237 on Day 1 was also observed for leg discomfort.

In summary, the trials have shown a lower rate of adverse outcomes in initially invasive strategy driven by a decreased need for future revascularizations with only a numerical trend towards fewer non-fatal myocardial infarctions and no difference in mortality.

However, rates of estimated ACR20, ACR50 and EULAR good response did show a numerical trend towards greater improvement in bDMARDs + MTX patients vs bDMARD monotherapy patients, consistent with prior research that demonstrated the superiority of bDMARD combination therapy over monotherapy [ 9 , 36 , 37 ].

However, direct comparisons of effect sizes revealed a numerical trend indicating higher vulnerability in females and non-elderly subjects, but these differences were not statistically significant between sexes or age groups.

Conclusion Short-lasting oxytocin inhibition through the OT-receptor antagonist atosiban did not significantly increase the incidence of migraine attacks in women with episodic migraine, although a numerical trend was observed.

Microbiological analyses, although based on pooled samples, indicated a numerical trend toward lower thermotolerant coliform counts in NDF-supplemented groups.

9 Intriguingly, some of the LABA/LAMA FDCs showed a numerical trend in protecting against cardiovascular SAEs, whereas other combinations showed a signal in increasing the risk of cardiovascular SAEs. 9 The frequencies of SAEs and deaths in RCTs of LABA/LAMA FDCs are low.

Compared with placebo, gilteritinib treatment showed a numerical trend of improvement in RFS (8.2 months) but this was not statistically significant (HR, 0.74; 95% CI, 0.41–1.34; p = .16), and the primary objective was not met.

A numerical trend toward reduced efficacy was observed in patients with the highest number of emetogenic risk factors; however, this finding was based on a small sample size and was associated with wide confidence intervals, indicating substantial uncertainty.

While both groups engaged in the phonemic fluency task, children with HFA showed a numerical trend toward reduced verbal output ( Table 1 ).

Notably, although the pooled analysis did not reach statistical significance, the meta-analysis showed a numerical trend toward increased risk (OR 1.37) accompanied by very high between-study heterogeneity (I2 = 87.2%).

It is also of interest that presence of SE alleles was significantly associated with arthritis progression, whereas exposure to cigarette smoking was not, although smoking showed a numerical trend for association with disease progression.

In the psychomotor domain, IVR simulation did not significantly enhance skill performance (SMD = 0.49, 95% CI: −0.24–1.22), despite a numerical trend favoring the intervention.

At week 12, a numerical trend was noted in favour of BTFC eye gel over BTFC eye drops for the investigators (96.0% and 93.2%, respectively) and patients (95.3% and 91.3%, respectively).

Along with recent findings of a numerical trend toward improvement in both OS and PFS with first-line lenvatinib plus pembrolizumab vs. lenvatinib monotherapy in participants with advanced HCC (LEAP-002; NCT03713593 ), although prespecified statistical significance for OS or PFS were not met, 20 these results provide additional evidence for pembrolizumab in the treatment of advanced HCC.

While the RBANS findings suggest a numerical trend, the absence of statistical significance and potential baseline confounding suggest the results are best viewed as exploratory and hypothesis-generating .

4.1%, P = 0.79) compare favorably with published series [ 33 , 34 ], and the MWA group showed a numerical trend toward lower cement leakage (2.9% vs. 4.1%), though this did not reach statistical significance likely due to our limited sample size.

Additionally, a numerical trend was also observed for domain 2 (OR: 1.56, 95% CrI: 0.97 to 2.54).

Examining the proportions of trials where multiple elements of different kinds disappeared simultaneously (lightest-shaded bars in Figure 6 ), the full model with factors motion and ocularity showed no significant effects (motion: χ 2 (1) = 1.2; P = 0.26; ocularity: χ 2 (2) = 5.1; P = 0.08; interaction: χ 2 (2) = 0.01; P = 0.99), even though there is a numerical trend across all ocularity conditions for the shared motion conditions to have a higher proportion of this type of disappearances than the different motion conditions.