While there may have been a numerical trend for inhibition of structural progression the trial was hampered by high discontinuation rates and a very short placebo period.
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“a numerical trend”
Sighted at
p=0.09
In the literature
However, the subgroup analysis of STEMI patients in PLATO showed only a numerical trend toward benefit without reaching statistical significance for the primary endpoint.
While the increase in PRE IL-8 did not reach statistical significance ( p = 0.056), a numerical trend toward higher levels in the PD group was observed.
Analyses conservatively suggest a numerical trend toward decreased atrophy in ALLO‐treated participants across all doses, with the greatest potential for regeneration in the 4 mg dose group.
In our cohort, the prevalence of prior cardiac and aortic surgery was notably high across all BMI categories, with a numerical trend toward more prior aortic interventions in lower-weight patients.
LANDMARK trial showed a numerical trend in favor of Myval, without reaching significance, as it was not properly powered for this comparison [ 20 ].
Nonetheless, adjusted means indicated a numerical trend toward higher Pparg expression in NW-MSCs compared to OW/OB-MSCs by day 14 of differentiation ( Figure 1E ).
While no statistically significant association was observed between starting dose and objective response rate (ORR) or clinical benefit rate (CBR), a numerical trend suggested that patients with shorter duration of response tended to have received lower initial doses [ 27 ].
While a previous study of patients with breast cancer and bone metastases showed that BESM patients had a numerical trend for persistently higher uNTX levels and an erratic uNTX variation during ZA treatment [ 20 ], in the present cohort bone markers did not differ according to metastatic compartment both at baseline and at 3 months.
The within-subject microbiological data (n = 10) suggested a numerical trend toward greater bacterial-burden reduction with HACCP’ER than with benzalkonium chloride, but the between-arm difference did not reach statistical significance.
A numerical trend of lower rates of serious infections among higher quartiles of baseline IgG level was observed (by baseline IgG quartile, serious infections rates per 100 participant-years [95% CI] were as follows: Q1, 1.63 [0.95–2.61]; Q2, 1.55 [0.90–2.48]; Q3, 1.51 [0.86–2.45]; and Q4, 1.11 [0.57–1.94]) [ 37 ].
Finally, there was a numerical trend for a correlation between CRT score and salary.
Despite the absence of significant differences between upper and lower locations for body and chair detection in full noise conditions, a numerical trend emerged.
10 The mean raw reading times summarized in Table 4 show a numerical trend opposite from the one of the RRTs in Region 3 such that the they condition exhibits higher mean raw reading times than the he condition for all antecedent types.
After propensity score matching, the association was attenuated and did not reach statistical significance (β = 0.26 [95% CI, −0.01–0.52]; p = 0.061), although a numerical trend toward longer procedural duration in the GA group persisted.
Nevertheless, a numerical trend toward symptom relief was observed, suggesting potential individual variability in response.
Moreover, exploratory stage stratified analyses showed a numerical trend towards greater absolute benefit in stage II/III disease than in stage I disease (hazard ratio 0.61 for stage II/III versus 0.76 for stage I), but the test for interaction between stage (I versus II/III) and carboplatin effect was not significant (P for interaction=0.63).
These results looked similar to those previously reported for cobimetinib plus paclitaxel without atezolizumab, but there was a numerical trend for a higher response rate in subgroups with PD-L1-positive tumor-infiltrating immune cells.
The main finding of interest in Experiment 2a is that speakers did not produce come more often when describing the Both scene than the Speaker scene; in fact, a numerical trend was observed in the opposite direction.
Conclusions In aSAH patients undergoing cranioplasty after DC, customized 3-D printed implants achieved significantly better anatomical restoration and showed a numerical trend toward fewer complications compared with autologous bone.
CV Safety In the entire study population, CV safety outcomes suggested a numerical trend favoring pegmolesatide in both DD-CKD and NDD-CKD patients.
In the severe hypoalbuminemia cohort (baseline serum albumin ≤2.8 g/dL), a numerical trend toward improved survival was observed with albumin supplementation; however, this effect did not attain statistical significance(HR 0.80, 95%CI 0.41–1.58) ( Figure 3 ). 5 Discussion In the propensity score-matched cohort of SIMI patients with comparable baseline albumin levels (mean 2.8 g/dL in both groups; p = 0.142), albumin administration demonstrated no mortality benefit across all evaluated endpoints: 28-day, 60-day, and 90-day mortality, as well as in-hospital mortality.
Nonetheless, there is a numerical trend broadly in line with what we found in Experiment 1: ORCs had higher RTs than SRCs. 4.5.
No effects on nutrient intake or digestibility were observed in beef steers on a feedlot diet supplemented with Bacillus , but there was a lower acetate:propionate ratio and rumen ammonia concentration, with a numerical trend towards higher pH levels post-feeding ( Dias et al., 2022 ).
In this analysis, there was a numerical trend in baseline platelet count and response (i.e., platelet level ≥ 50 × 10 9 /L that is also 20 × 10 9 /L higher than baseline) decreasing from 71% in 18 patients with low TPO levels (< 115 pg/mL), 45% in eight patients with normal TPO levels (115–228 pg/mL), and 15% in five patients with high TPO levels (> 228 pg/mL) [ 35 ].