“a notable trend”

Furthermore, the figure highlighted a notable trend that initial approvals tended to be associated with a more extensive array of PMRs compared to approvals for expanding indications.

1 Introduction The incidence of metabolic syndrome and diabetes has been steadily increasing over the years, imposing significant economic burdens, with a notable trend of affecting younger individuals ( Rooney et al., 2023 ).

A notable trend was the predominance of publications in Dental Public Health, while specialties like Oral and Maxillofacial Surgery and Endodontics had no representation.

Although the number of RBC transfusions did not reach statistical significance, a notable trend suggested a potential increase in mortality.

There is a notable trend in using generative models 24 to investigate data from weak supervisory sources to solve this bottleneck.

However, the calculated effect size was large (r=0.52), indicating a notable trend toward a higher number of terminal branches in male specimens.

Currently, IBD afflicts more than 6.8 million people worldwide, with a notable trend toward younger age.

In 2022 and 2023, monthly precipitation patterns in Chesapeake Bay varied, but a notable trend for both years was the increased precipitation in December following a dip below the annual average in November ( Figure S5 ).

Over the past decade, there has been a notable trend towards reforming learning environments in dental education, with an increase of research on active learning techniques [ 16 – 18 ].

Anti-tumor effect of ZSTK474 in vivo A notable trend was observed during the monitoring of subcutaneous tumor volume.

However, there is a notable trend indicating a rise in incidence attributed to the widespread adoption of ART and ovulation induction.

With regard to the technical aspects of primary THA, there is a notable trend toward an increasing use of uncemented femoral stems over the years [ 3 , 4 ].

There was a notable trend indicating dose-dependent QUIN toxicity on oligodendrocytes where the LD 50 for N19 is 0.5 μM and for N20.1 is 1 μM for 72 hours.

A notable trend was observed up to 50% SCG–ALS content (relative to oven-dry fibers), where MOE increased by 1.09 times compared to the 40% formulation.

Despite this, a notable trend was the occurrence of hyperopic PEs across all formulas, likely due to the reliance on constants optimised for normal eyes.

Discussion During the decades, there has been a notable trend in the increase of thyroid cancer, although the specific reasons for this trend are still undefined. 30 Many genetic factors involved in thyroid cancer have been discovered.

System-Level Integration of ISF Biosensors A notable trend in the recent literature is the shift from “sensor-on-a-bench” prototypes to fully packaged devices that address wearability, power, and telemetry.

With increasing patient age, there was a notable trend toward a higher prevalence of triple osteotomy, whereas the proportion of Salter osteotomy decreased accordingly.

The results revealed that responses generated by GPT achieved statistically significant ratings in empathy and readability, with a notable trend toward statistical differences in relevance and medical accuracy compared with authentic patient portal message responses.

Comparable schemes exist or are under consideration internationally ( Boulet and van Zanten, 2014 ; Sehlbach et al., 2018 ), marking a notable trend towards continuing assessment of competency.

Despite the lack of statistical significance, the FCD group exhibited a notable trend of increased proportion of astrocytes, inhibitory and excitatory neurons, as well as a decrease in oligodendrocytes, compared with the control group.

Although the percentage of T‐cells, neither Th cells or CTLs, did not increase with any of the individual components, we found a notable trend toward an increase of intracellular IFN‐γ levels in CTLs and Th cells, particularly when stimulated with MSLN3 and MSLN4 sequences.

Similarly, Table 4 and Table 5 highlight a notable trend in body image satisfaction across different age groups.

However, as the annealing temperature increases, there's a notable trend towards a decrease in zeta potential.

The effect of CWYW and enzyme supplementation on VFA profiles showed a notable trend.