While sepsis alone did not reach statistical significance in the adjusted model, sepsis with septic shock showed a notable trend toward increased mortality risk (OR = 2.14, p = 0.08).
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Although not significant, this analysis also yielded a notable trend in which birds treated with E2 tended to have more NeuN+ cells in HVC than birds treated with FAD (F (1,53) = 3.2, p = 0.081; Figure 1C ).
We also found a notable trend towards a significant increase in the cell density of CD8 (Fig. 7a , p = 0.082) in ADC.
However, for the HIV- group ICAM-1 levels exhibited a notable trend, with higher concentrations in patients with active NCC compared to those with inactive NCC (adjusted p = 0.0826).
Although not all predictors were significant, there was a notable trend, with the solvent water/methanol showing a positive influence on FRAP levels (coefficient = 43.3467, p = 0.084), though this did not reach statistical significance. 4.
6 ) but a notable trend ( P = 0.084 and 0.066) toward higher magnitudes in response to the noisest face pictures compared with the rest of WM voxels.
A notable trend in surgical approaches for oral cancer treatment over the two periods studied was observed with open surgery ( p = 0.086) and en bloc resection ( p < 0.001) being used less common in the more recent period.
We found no significant associations between proctitis severity and patients' age, sex, ECOG performance score, comorbidities, or tumor location; however, there was a significant correlation between the planning target volume and proctitis (P=0.038), as well as a notable trend for a relationship between CTV and proctitis severity (P=0.089) ( Table 3 ).
Although these differences did not reach statistical significance, there was a notable trend toward longer surgery duration (median: 253 min, IQR: 217.5–295.5 vs. median: 282.0 min, IQR: 248.75–330.0; p = 0.089) and increased nasogastric tube aspiration (18% vs. 41%; p = 0.064) in the HU ≤ 37 subgroup.
We observed significantly lower Il12p40 mRNA expression (p = 0.032) as well as a notable trend toward decreased Tnfα expression (p = 0.089) in Il10 −/− ; Myd88 −/− compared to Il10 −/− mice ( Figure 7C ).
There was a notable trend for a higher RVP in the healthy/FS + group compared to the healthy/FS - group, which did not reach statistical significance (p = 0.0898).
Additionally, in substudies 1 (ASA use in mechanical prosthesis and concomitant atherosclerotic disease) and 6 (OAC after mitral valve repair), there was also a notable trend toward higher mortality in the non-AT groups at 6 months ( P = .09 and P = .08, respectively).
However, there was a notable trend ( P =0.09) towards the reduction in the density of PV-positive neurons in 13-month-old GK rats in comparison with 3-month-old GK rats (16% reduction) although this did not reach statistical significance ( Figures 5 B and 5 D).
The multivariable analysis revealed a notable trend toward a decrease in unintended pregnancies in the postintervention period ( P = .09).
Although age > 65 years showed a notable trend (OR = 5.91), it did not reach statistical significance in the multivariable model ( P = .092).
A notable trend was also observed for Clostridium UCG‐014, a member of the Clostridia class, which exhibited increased abundance following FA supplementation ( p = 0.093).
Research has shown that Lactobacillus acidophilus supplementation in broilers significantly improves feed efficiency ( p < 0.05) while reducing abdominal fat deposition, with a notable trend toward enhanced humoral immunity (IgG, p = 0.093) ( Liu et al., 2025 ).
When examining organ failure (OF) and mortality, the BAL + group exhibited a notable trend towards higher rates of central nervous system (CNS) failure (20.3% vs. 16.1% in BAL- TP; p = 0.094) and multiple organ failure (MOF) (19.4% vs. 15.3% in BAL- TP; p = 0.095).
While Zn levels in AML patients showed a notable trend toward higher values in females ( p = 0.094).
There was a notable trend towards decreased 11β-13,14-dihydro-15-keto prostaglandin F2α in rare melanomas compared to cutaneous (H = 6.378, p = 0.095) and enrichment in 13-OxoODE in acral and mucosal melanoma (H = 6.667, p = 0.083) ( Supplementary Figure S3 .
The interaction effect of drug × condition did not reach significance; however, a notable trend effect was observed ( F 2,10 = 3.0, p = 0.095, n G 2 = 0.056), such that PSE values appeared lower for psilocybin vs. placebo in the OS and PS conditions.
33.3% in the NBP group, p = 0.93), we observed a notable trend toward lower in‐hospital mortality in the NBP group (52.9% in the placebo group vs. 33.3% in the NBP group, p = 0.098), along with a substantial increase in the proportion of patients with a CPC score of 3 (5.9% in the placebo group vs. 16.7% in the NBP group) (Figure 2 ).
Additionally, there was a notable trend towards statistically significant lower mental toughness in the general surgery category when compared to other surgical specialties [ F (1.95) = 2.78; p = .099; η 2 = .028].
However, when sex drive is added as an additional covariate, the sex difference is no longer significant, although there is still a notable trend in the predicted direction ( F (4, 346) = 2.70, p = .10).
However, a notable trend of interaction between TFE and LPS was detected respect to ADG (0.05 < P < 0.10).