Of these, only Emoclot ( n = 1019) had more than 1000 treatment years, showing a nonsignificant trend toward reduced inhibitor development compared with Advate (IRR, 0.00; 95% CI, <0.01 to 1.09).
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In the literature
A study in Copiah county, Mississippi, USA reported a nonsignificant trend in which the prevalence of ET was higher in whites than African–Americans [ 33 ].
Rosuvastatin treatment showed a nonsignificant trend toward decreasing the incidence of MACE.
Moreover, a nonsignificant trend towards higher levels of Bacteroidetes phylum and the Bacteroidaceae family were also found ( Supplementary Table S1 ).
However, we found a nonsignificant trend towards a reduced risk of all-cause mortality, ischemic S/SE and net clinical outcome between edoxaban 60 mg daily and warfarin.
Two of this studies involved SSRI[ 12 , 23 ] and two monoamine oxidase inhibitor (MAOI).[ 24 , 25 ] Response rates in the acute stages of treatment in all the four studies showed a nonsignificant trend in favor of combined medicationpsychological treatments over medication alone, like in the present study.
Of note, ROS production in the liver of obese mice was almost three times higher than that in lean mice, despite only a nonsignificant trend for reduction in liver RCR, suggesting that liver ROS production may be more dependent on nonmitochondrial sources in obese mice compared to lean mice.
HFNO showed a nonsignificant trend in reducing endotracheal intubation.
Higher team scores on neuroticism showed a nonsignificant trend toward more aggressive behavior, OR 1.23 (95% CrI 0.90–1.53).
Two-sided Fisher exact testing revealed no statistically significant difference in detection rates between grade 3 versus grade 4 ( P = .421) or grade 2 versus grade 3 ( P = 1.000), with a nonsignificant trend toward lower detection in grade 4 relative to grades 2/3 combined.
Among patients without gastrointestinal symptoms, there was a nonsignificant trend toward elevated VAT/SAT ratio in those who died, which was not seen in patients with gastrointestinal symptoms.
There was also a nonsignificant trend for a positive correlation between the AAAQ inclined/indulgent subcale (weak “approach”) and the SRC task approach bias score.
There was a nonsignificant trend towards a greater rate of first time attendance to ANC in intervention C compared to controls ( Table 2 ).
We investigated the contribution of PHE interactions with an analysis correlating A1c values to number of touchpoints and observed a nonsignificant trend towards correlation between these factors.
Of note, this growth factor was not affected by the NSAID type (treatment effect) and time effect, although carprofen showed a nonsignificant trend of higher values at 6 h ( Figure 2 B).
Although there were significant increases in Bglap expression in the LPS-stimulated cultures following parecoxib treatment, a nonsignificant trend towards a decrease was also noted in unstimulated cultures ( Figure 4(f) ).
Another observational study found that replacing saturated fat with low glycemic index carbohydrates was associated with a nonsignificant trend toward lower risk of myocardial infarction, while replacement of saturated fat with high glycemic index carbohydrates was associated with significantly higher risk (hazard ratio: 1.33; 95% CI: 1.08, 1.64) [ 37 ].
10 , 12 , 29 However, we did find a nonsignificant trend of 1.7‐fold higher enhancement ratio in recurrent stroke patients than that in stable patients at follow‐up MRI.
One explanation may be lack of power, as there was still a nonsignificant trend toward worse CPP in those with cyclic CHC ineffectiveness.
3.6%, p = 0.06) compared with the younger patients, although it was a nonsignificant trend.
A larger sample size is needed to reliably assess the effect of metreleptin therapy on mortality risk in the GL subgroup, where a nonsignificant trend towards lower mortality was observed, as well as in subgroups of specific GL and PL subtypes.
Mortality results were modified (RR 0.92, 95% CI 0.83–1.02, p = 0.098), with a nonsignificant trend of lower mortality rates in patients randomized to SSD.
We found a nonsignificant trend towards a greater effect of familiarity for inverted faces: 51 ms [26, 77] for upright faces, and 83 ms [50, 116] for inverted faces (difference 33 ms [–10, 74]).
A subgroup analysis limited to total gastrectomy showed a nonsignificant trend toward increased IH risk after LG (OR 6.12).
A nonsignificant trend toward increased serious adverse events or treatment discontinuation was observed (odds ratio = 1.52; 95% CI: 0.66; 3.50), with low heterogeneity.