“a nonsignificant trend”

30 The current study found a nonsignificant trend toward higher LV mass-to-volume ratio, but significantly lower LVEF and MCF in the LFS group, which suggests that age might be related to, but not the only factor contributing to LFS.

Oseltamivir ablated overall viral diversity in lean mice, with a nonsignificant trend to reduced numbers of SNVs and total Shannon’s entropy in treated lean mice compared to no difference in treated OB mice ( Fig. 4A and B ).

In the landmark analysis, time‐to‐event demonstrated a nonsignificant trend toward lower MACE with IVL, suggesting that early events within 30 days may have driven the overall hazard difference (Supporting Information S1: Figure 4 ).

In patients younger than 80 years (mRS 0–2: aOR, 1.52; 0.84–2.77; p = 0.166) and without stroke history (aOR, 1.60; 0.85–3.06; p = 0.152), tenecteplase therapy was associated with a nonsignificant trend toward better functional outcomes at 90 days.

26 Both transcripts showed a nonsignificant trend toward upregulation in the hippocampi of tau‐expressing mice, with no significant effect of Nmnat1 coexpression (Fig.

17 Morphine and methadone have shown a nonsignificant trend toward greater pain relief compared with the TCAs nortriptyline and desipramine. 32 Adverse events included those usually reported with opioid analgesics, including nausea, constipation, dizziness, xerostomia, anorexia, and sedation/somnolence. 31 , 32 Despite the efficacy of opioids, opinion varies about their place in the treatment of PHN.

Mice treated with ch α-GA 1 and ch α-GP 1 antibodies also showed a nonsignificant trend toward improvement in this behavioral assay ( Fig. 4 D ).

Interestingly, a nonsignificant trend suggested a protective effect with GLP-1 RAs ( 4 ).

In addition, the vNOTES group had lower pain scores and shorter operative times but a nonsignificant trend toward higher complications, mostly due to bleeding. 49 A systematic review and meta-analysis comparing vNOTES to laparoscopic hysterectomy published in 2020 included one RCT and five retrospective cohort trials. 50 Authors found that vNOTES had shorter operative times, shorter length of stay, and lower estimated blood loss with no difference in complications, readmissions, and pain scores.

Unexpectedly, in our survey, only children with TD+ADHD demonstrated a significantly elevated risk of cyberbullying perpetration, with a nonsignificant trend toward increased risk compared with children with TD alone and ADHD alone (supplementary Table S7, not surviving Bonferroni correction).

Middle deltoid and biceps brachii activities increased significantly, with a nonsignificant trend toward higher upper trapezius activation.

However, IL6 mRNA levels showed only a nonsignificant trend toward change among groups ( Fig. 5 D).

One week after treatment, the ORS-treated group showed a nonsignificant trend toward a lower SBP (194.1 ± 18.3 mmHg) relative to control (209.0 ± 7.8 mmHg).

Results also showed a nonsignificant trend toward better performance in the incongruent trials of the Flanker Squared Task, an effect that was mediated by reduced perceived exertion. status released display-pdf yes is-in-collection-domain yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Revised 2025 Jun 23; Received 2025 May 14; Accepted 2025 Jul 16; Issue date 2025 Oct. 1.

In our patient cohort, AR1 and AR3 isoforms showed a nonsignificant trend toward higher expression in female patients (n = 10 per sex), with greater isoform variability among male patients in a smaller subset.

Morphometric analysis revealed a nonsignificant trend toward decreased volume of K5-expressing cells at day 2 followed by recovery to normal levels by day 4 (Figure 9A , although the distribution of the staining was altered, as shown in Figure 7 ).

DSRT achieved double the rate of FPR, although the FPR rate of SSRT was only 24%, the lowest observed in any RCT 93 – 103 for EVT (Table 3 ), and DSRT was associated with a nonsignificant trend towards a higher incidence of sICH.

On the other hand, a nonsignificant trend persisted in diabetes mellitus and dyslipidemia relative to DP and HR values, as well as in the influence of the presence of smoking and positive hereditary factors in relation to SP, DP, and HR values ( Table 5 ).

Injection of LV-CTSA-IRES-NEU1-GFP did not alter levels of the synaptic proteins in WT mice but led to a significant increase of VGLUT1 and PSD-95 levels in Hgsnat P304L mice, whereas the levels of Syn1 showed a nonsignificant trend toward an increase ( Figure 10 ).

The HR for adjuvant nivolumab shifted from above one in the univariable analysis to below one after adjustment for ypT and ypN (HR 0.602 [0.240–1.511], P = 0.280), suggesting a nonsignificant trend toward reduced DFS risk.

Although we only observed 11 patients with MDR TB and diabetes, we found a nonsignificant trend toward an increased median time to sputum culture conversion among MDR TB patients with diabetes.

There was a nonsignificant trend toward higher AF recurrence in patients with worse glycemic control.

One explanation for the marked difference could have included differences in health status, as there was a nonsignificant trend for the Mexican sample to be older and more impaired (Table 1 ).

Abatacept also induced a decline in the number of circulating CD4 + CD25 high cells, and we observed a nonsignificant trend for this change to associate with C-peptide level decline.

While the ACE index showed a nonsignificant trend in α-diversity (Fig. 1 C), β-diversity assessed by principal coordinates analysis (PCoA) based on UniFrac distance revealed significant separation between the OVX and Sham groups ( P = 0.005) (Fig. 1 D).