In a more recent publication, Miiler et al [ 5 ] observed a nonsignificant trend toward improved outcomes with initial combination therapy, although differences in time to surgery between groups may have influenced this finding.
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miR‐181a treatment of old mice resulted in a nonsignificant trend for increased SDH intensity (Figure 6g ).
Patient outcomes were similar between the conservative and liberal groups including 90-day mortality (14.7 vs 35.2%; p = 0.091) and ICU LOS (8.5 vs 12.5 d; p = 0.094); however, there was a nonsignificant trend toward better outcomes in the conservative group.
A nonsignificant trend toward a growing-into-deficit for intelligence has been observed in children undergoing surgery for transposition of the great arteries from 5- to 10-year post-PICU ( 9 ).
However, meta-regression revealed a nonsignificant trend for increase in the anxiety-reducing effects of music interventions with increasing maternal age.
The relationship between CPAP adherence and health literacy has been evaluated in only two trials, in which health literacy was a secondary outcome; one found a nonsignificant trend toward poor adherence with low health literacy, and the other found no significant relationship [ 8 , 17 ].
Moreover, the recent meta-analysis also found a nonsignificant trend of higher repeated continence surgery rates in patients received SIMS [ 28 ].
In breast invasive carcinoma no predictive value was observed by SLC6A14 , SLC12A4 or SLC25A15 alone, but there was a nonsignificant trend for reduced survival in SLC6A14 -high combined with SLC12A4 -high or SLC25A15 -high expression (Extended Data Fig. 7b ).
This finding was observed as a nonsignificant trend when considering total NK cells but significant in case of conventional regulatory (7.65 vs. 11.12) as well as dysfunctional NK cells (9.08 vs. 19.65).
A nonsignificant trend also emerged indicating fewer beliefs about the relationship between genetics and race.
Viral integration was associated with increases in somatic DNA copy number and a nonsignificant trend toward a higher mutational burden, suggesting that tumors with HPV integration might be associated with more immunogenic tumors [ 23 ].
A meta-analysis of twenty trials involving 2195 patients showed summary risk ratio for contrast-related nephropathy to be 0.73 (95% confidence interval: 0.52 to 1.0; P = .08), a nonsignificant trend towards benefit in patients treated with acetylcysteine [ 85 ].
In the TN cohort, there was a nonsignificant trend for lower TILs for patients who received chemotherapy for metastatic disease prior to metastasis biopsy, as compared to patients undergoing biopsy before starting first-line treatment (median 2%, Q1 2% to Q3 5%; median 5%, Q1 23% to Q3 10%, respectively; p = 0.104).
Jones et al., for example, found that adults with class II obesity (BMI = 35.0-39.9) who had inaccurate weight perceptions had less weight concern, less distress regarding overeating, less distress regarding control overeating, less emotional overeating, less eating disinhibition as well as exhibited a nonsignificant trend toward less time spent dieting [ 28 ].
Levels of phosphorylated p38 mitogen-activated protein kinase (p-p38 MAPK T180/Y182) were higher in dorsal NSPCs, and p-Akt S473, upstream of mTORC1, exhibited a nonsignificant trend towards higher levels in dorsal NSPCs, likely because of feedback from mTORC2 ( Fig S2C ).
A nonsignificant trend towards slightly reduced deep sleep was noted, which is consistent with the results of previous studies.
There was no difference between assPD and IHD for hospitalizations with cardiovascular diagnoses and a nonsignificant trend towards a higher number of admissions with infectious disease diagnoses for patients with assPD during the two years following the first CSS.
In this study, we found a nonsignificant trend toward age-related gray matter volume loss in the temporal network (network e).
It seems likely that reduction of the distress caused by tinnitus resulting from participation in the iCBT(T) program led to the observed reductions in anxiety and depression. There was a nonsignificant trend for participants whose tinnitus started 1 month or less before commencing the iCBT(T) program to show greater improvements in their 4C and SAD-T scores than participants whose tinnitus started 6 months or more before commencing.
Additionally, our analysis found that completing at least 30 mL/kg of fluid resuscitation within the first hour did not confer a survival benefit and showed a nonsignificant trend toward increased odds of mortality.
Finally, a retrospective study from Italy found that interferon- β was associated with a nonsignificant trend towards lower birth weight arising from 38 pregnancies (versus 202 nonexposed pregnancies), but that development up to 18 months was indistinguishable between exposed and nonexposed pregnancies [ 30 ].
We also evaluated PD-L1 expression levels in human monocytes (CD33 + CD66b − CD14 + ) and found a nonsignificant trend towards increased PD-L1 expression in the anti-PD-1-resistant samples ( Supplementary Fig. 7f ).
Alcohol intake showed a nonsignificant trend toward an association with diverticulosis.
53 In addition, rest breaks were found to be protective against severe increases in creatinine and a nonsignificant trend that increasing USG was associated with increases in creatinine.
However, there was a nonsignificant trend toward worse final BCVA values in patients whose PCR occurred during earlier surgical stages.