“a nonsignificant trend”

Intriguingly, although high PD-L1 seemed to be associated with RR independently of NLR, a nonsignificant trend toward better OS in patients with low NLR and high PD-L1 as compared to those with high NLR and high PD-L1 was observed.

Teglicar reduced basal insulin levels; a nonsignificant trend toward a reduction of basal blood glucose was also observed, whereas EGP, glucose infusion rate (GIR), and peripheral insulin sensitivity (GU), assessed with a hyperinsulinemic-euglycemic clamp, did not differ between treated animals and controls.

Diabetes mellitus was not associated with RAP, but showed a nonsignificant trend toward an increased risk of CP (OR, 3.77; 95% CI, 0.98–14.45; 95% PI, 0.12–120.85; I 2=0%, τ2=0; k=4 studies, N=169 patients) ( Figs. 3 and 4 ; Supplementary Figs. 2 , 4 , and 6 ).

However, there was a nonsignificant trend toward lower stress scales as measured by DASS-21 in the postimplementation group.

Pravastatin was associated with improved OS (HR: 0.674, 95% CI: 0.471–0.964) but showed a nonsignificant trend toward improvement in DFS (HR: 0.742, 95% CI: 0.532–1.037) [ Table 2 ].

In contrast to our surprise finding of increased mortality associated with receiving larger donated kidneys, Kasiske et al showed a nonsignificant trend toward better survival beyond 4-months for small recipients receiving large kidneys (although there was a trend toward poorer survival within the first 4-months).

For RSV wheezing illnesses, there was no association with rs7216389 genotype in White children (Figure 1C ), while in Black children there was a nonsignificant trend for rs7216389‐TT asthma‐risk genotype having a longer time‐to‐RSV wheezing illness ( p ‐value .054, Figure 1D ).

A summary of the quantification of these data are presented in Figure 7 ; imeglimin produced a nonsignificant trend towards greater β‐cell neogenesis with 21 and 28% mean increases in duct‐associated insulin‐positive single cells and clusters compared to control, respectively. 3.2.4.

While HRD status was not statistically associated with differences in patient outcome for patients treated with combined chemotherapy and endocrine therapy, a nonsignificant trend of poorer outcome for patients with HRD tumors was observed for patients treated with adjuvant endocrine therapy only.

However, the binary meta‐analysis showed a nonsignificant trend regarding the protective effect of vaccination on AMH levels.

The group with LBW also had higher blood pressure and a nonsignificant trend toward a lower mGFR as compared with those in the NBW group.

There was comparable neutralization for both cell lines within cohorts, with a nonsignificant trend toward reduced neutralization for the delta variant (Table S2 ).

In another meta-analysis that included 57 studies of postmenopausal women randomized to HT or control (PBO or calcium/vitamin D) for at least 1 year, there was a nonsignificant trend toward a reduced incidence of vertebral (RR, 0.66; 95% CI, 0.41–1.07; 5 trials) and nonvertebral fractures (RR, 0.87; 95% CI, 0.71–1.08; 6 trials) with HT and consistent, favorable effects on BMD [ 31 ].

Villumsen et al 63 observed a nonsignificant trend toward decreased need for TNF-α inhibitor initiation (aIRR: 0.56, 95% CI: 0.32–1.00).

There was a nonsignificant trend towards more sprue-like histologic features in patients taking olmesartan compared to patients taking other ARBs.

In the past, a Cochrane review on antiplatelet therapy after SAH showed a nonsignificant trend toward a lower occurrence of DCI and improved clinical outcome but was possibly offset by a concomitant nonsignificant increase in hemorrhagic complications [ 25 ].

Significant time effects show that over 18 months, the participants improved significantly in depressive, manic/hypomanic, and anxiety symptoms, with a nonsignificant trend toward improvement on the LIFE-Panic scale.

Fusion protein scFv425:sTRAILmR1–5 showed superior apoptotic activity compared to the corresponding wild-type sTRAIL fusion protein on half of the EGFR-positive solid tumor cell lines tested and showed a nonsignificant trend to higher apoptotic activity on the other cell lines.

There was a nonsignificant trend to increasing mean force requirement from the anterior to the posterior ethmoid sites.

Dexiostoma showed a similar persistence across all combinations of competitors, despite a nonsignificant trend to lower persistence when Paramecium was present.

25 Regarding the objective sleep architecture, the authors of the study Latreille et al found a nonsignificant trend towards a reduced duration of the REM phase in PNES patients compared to individuals with epilepsy. 50 This contradicts the Bazil et al results, which found the opposite relationship.

Among those with positive PD‐L1 expression (TC1/2/3 or IC1/2/3) treated with atezolizumab, an elevated pretreatment LDH level was associated with a nonsignificant trend of worse PFS and OS; this likely reflected the small patient numbers.

Behaviorally, SERT −/− rats showed a nonsignificant trend for more accurate responses to the CS−.

Being older than 70 years of age, having history of a nonfatal stroke, poor physical activity, and severe edentulism were significantly related to mortality, whereas individuals with primary school education only, a poor diet, and fasting glucose levels ≥126 mg/dL had a nonsignificant trend for a higher mortality rate ratio [ Table 1 ].

However, we observed a nonsignificant trend of QFR increase along with stent expansion, which is also surprising.