A meta-analysis of four RCTs and eight observational studies of DEB-TACE versus conventional TACE found a nonsignificant trend in 1-, 2-, and 3-year survival in favor of DEB-TACE, and concluded DEB-TACE to be non-superior to conventional TACE ( 63 ).
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10 As LR is sometimes considered a traditional model and not an ML algorithm, a meta‐analysis concluded that ML was superior to the LR model in terms of mortality prediction after cardiac surgery, with a nonsignificant trend toward the better predictive ability of each ML algorithm.
Adverse event rates showed a nonsignificant trend favoring HM (RR 0.56, 95% CI [0.06, 5.26]; low-certainty evidence).
In agreement with previous descriptions of the CD model, mice presented an increase in the heart weight/body weight ratio ( Figure 5a ) and a nonsignificant trend on muscle proportion of the left ventricle ( Figure 5—figure supplement 1 ) consistent with cardiac hypertrophy.
They were also more likely to be male, in comparison to those with NICBP, and a nonsignificant trend was seen comparing those with CIBP with those without.
Whereas cervical cancer mortality rates have been declining significantly in almost all age groups, a nonsignificant trend of increasing mortality rates was found among women 20 to 34 years of age after 2004 (APC, 6.4%; 95% CI, -2.6 to 16.2).
Use of post-transplant cyclophosphamide (PT-CY) showed a nonsignificant trend toward more frequent application in the early mortality group.
Kaplan–Meier survival plots suggested a nonsignificant trend toward better survival outcomes with higher miR-5000-3p expression.
In this study, we observed a nonsignificant trend toward greater numbers of gram‐positive infections in patients with Hohn and PICC catheters, as might be expected.
There were no pre‐existing differences in the final 3 days of trial‐based self‐administration data between eNpHR3.0 and eYFP groups, although there was a nonsignificant trend toward an interaction effect between day and group for heroin infusions (Table 1 ).
The only randomized trial to date that has compared a 5-day regimen of concomitant therapy with a 10-day regimen 58 revealed a nonsignificant trend for higher cure rates with the longer regimen (96% with 10 days versus 90% with 5 days).
However, a similar review reported a nonsignificant trend in favor of CBT over usual care for the reduction of anxiety and depression in COPD patients. 136 Although mixed, the literature indicates that CBT is likely effective for reducing anxiety and depression among COPD patients.
Using a paired analysis, we confirmed that the slow oscillation in the primary focus (i.e., the LH) started significantly before the one in the FC (−490 vs −325 ms), while there was only a nonsignificant trend when comparing to the RH onset (−365 ms; Fig. 6 D ).
No change in arthritis score was observed upon physical examination, but patient-reported outcomes did show a nonsignificant trend towards a response.
Both of these studies, however, noted a nonsignificant trend of lower yield from plants with higher defoliation compared with the controls without adults or lower levels of defoliation.
For the small number progressing to UENS more than four in either group there was a nonsignificant trend toward lower thigh IENFD and worsening of nerve conduction study values (Fig. 2 ).
There was a nonsignificant trend toward better perceived QoL and decreased disability by SF36 and WHO-DAS 2.0.
fraxineus showed significant increases in ITS‐2 read percentages in leaflets and petiole base, the biotrophic genus Exobasidium showed significant increase in ITS‐1 and ITS‐2 read proportions in leaflets, while the biotrophic genus Phyllactinia showed a nonsignificant trend of increase in ITS‐1 and ‐2 read percentages in leaflets.
Similarly, another study found a nonsignificant trend toward better long-term response in patients with definite SLE compared to incomplete SLE.
For example, a nonsignificant trend was shown by observed stations in the wet season (Fig. 2c , circle) at the bottom of the CLRB, and the same trends were detected on the CRU measuring point near the observed precipitation station.
However, a nonsignificant trend toward attenuation of the induction of hypertrophic gene markers was observed in female double-knockout mice ( Figures 2Q,R ), whereas no differences were detected in male mice ( Figures 2L,M ). 3.5 TG-582 mice do not show a baseline cardiac phenotype We next examined the cardiac effects of miR-582 overexpression in TG-582 mice.
Although not powered to demonstrate statistically significant treatment differences, a nonsignificant trend of greater improvement was observed for ulotaront treatment compared with placebo for most outcomes.
There was a nonsignificant trend toward a benefit, but side effects of drowsiness were substantial.
12 Moreover, in this setting, two randomized trials reported that the combination of carboplatin–gemcitabine–bevacizumab or carboplatin–paclitaxel–bevacizumab administered until progression of disease, significantly increases PFS with an hazard ratio of 0.48 13 with a nonsignificant trend in OS increase (hazard ratio 0.82). 14 However, the unsatisfactory results obtained with salvage chemotherapy have elicited investigators to detect novel biological agents capable of achieving a better control of the disease. 15 In the last two decades several changes in all fields of ovarian cancer management have occurred, from the diagnosis, to the treatment, to the translational research.
The TNF-α receptor mRNA was strongly upregulated during chronic alcohol exposure, with a nonsignificant trend toward an additional increase during withdrawal.