Barely Significant
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“a nonsignificant trend”

5,407 sentences · 5,407 papers · 7,516 search hits before verification · confirmed specimen

Sighted at

p<0.1

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

In subgroup analyses, extended thromboprophylaxis with rivaroxaban showed a nonsignificant trend towards less efficacy than short-term enoxaparin in patients with active cancer on day 35 (9.9% versus 7.4%; RR 1.34; 95% CI 0.71–2.54), 64 , 65 while clinically relevant bleeding was more frequent with rivaroxaban than with enoxaparin plus placebo onday35 (5.4% versus 1.7%, 64 RR 3.16; 95%CI 1.17–8.50; authors’ calculation).
In another meta-analysis that included 57 studies of postmenopausal women randomized to HT or control (PBO or calcium/vitamin D) for at least 1 year, there was a nonsignificant trend toward a reduced incidence of vertebral (RR, 0.66; 95% CI, 0.41–1.07; 5 trials) and nonvertebral fractures (RR, 0.87; 95% CI, 0.71–1.08; 6 trials) with HT and consistent, favorable effects on BMD [ 31 ].
Teglicar reduced basal insulin levels; a nonsignificant trend toward a reduction of basal blood glucose was also observed, whereas EGP, glucose infusion rate (GIR), and peripheral insulin sensitivity (GU), assessed with a hyperinsulinemic-euglycemic clamp, did not differ between treated animals and controls.
In contrast to previous data on aromatase inhibitors, which suggested a nonsignificant trend toward increased risks of myocardial infarction and ischemic stroke in women with breast cancer, our study found that women with abdominal obesity—regardless of aromatase inhibitor treatment—had significantly higher risks of CVD and stroke alone [ 29 ].
40 A meta‐analysis on the association between low serum magnesium and fatal CHD, which included the 2 studies discussed above, 11 , 14 found a nonsignificant trend towards an increased risk. 9 However, this meta‐analysis also included 2 studies with SCD as outcome of interest which, judging from the Forest plot, were mainly responsible for this observed inverse effect. 2 We analyzed SCD independently of CHD and found a significantly elevated risk for SCD in participants with low serum magnesium levels.
Moreover, while there was no association between concomitant use of DOACs and antiplatelet agents and the risk of all‐cause mortality among male patients (weighted HR, 0.95; 95% CI, 0.56‐1.60; I 2 , 0.00), there was a nonsignificant trend toward an increased risk among female patients (weighted HR, 1.64; 95% CI, 0.98‐2.72; I 2 , 0.00).