For men, there was a nonsignificant trend towards reduced mean IGF-I levels with increasing smoking exposure ( P trend =0.11), but no association after adjustment for IGFBP-3.
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lappa prophylactic group, there was a nonsignificant trend toward decreased release of the pro-inflammatory cytokines TNF-alpha and IL-12.
Among normal-weight girls, those with CPP/EP had higher body weight ( P = .03) and greater ΔH–TH SDS ( P = .009) than their peers with npPBD, as well as more advanced bone age ( P = .02) and higher IGF-1 SDS ( P = .001); they also showed a nonsignificant trend toward a larger uterine anteroposterior diameter.
Remarkably, there was even a nonsignificant trend for better memory for single items than for adjacent items encoded under stress (i.e., a reversed recognition priming effect).
In subgroup analyses, extended thromboprophylaxis with rivaroxaban showed a nonsignificant trend towards less efficacy than short-term enoxaparin in patients with active cancer on day 35 (9.9% versus 7.4%; RR 1.34; 95% CI 0.71–2.54), 64 , 65 while clinically relevant bleeding was more frequent with rivaroxaban than with enoxaparin plus placebo onday35 (5.4% versus 1.7%, 64 RR 3.16; 95%CI 1.17–8.50; authors’ calculation).
However, we observed a nonsignificant trend of QFR increase along with stent expansion, which is also surprising.
Behaviorally, SERT −/− rats showed a nonsignificant trend for more accurate responses to the CS−.
Dexiostoma showed a similar persistence across all combinations of competitors, despite a nonsignificant trend to lower persistence when Paramecium was present.
There was a nonsignificant trend to increasing mean force requirement from the anterior to the posterior ethmoid sites.
Significant time effects show that over 18 months, the participants improved significantly in depressive, manic/hypomanic, and anxiety symptoms, with a nonsignificant trend toward improvement on the LIFE-Panic scale.
In the past, a Cochrane review on antiplatelet therapy after SAH showed a nonsignificant trend toward a lower occurrence of DCI and improved clinical outcome but was possibly offset by a concomitant nonsignificant increase in hemorrhagic complications [ 25 ].
In another meta-analysis that included 57 studies of postmenopausal women randomized to HT or control (PBO or calcium/vitamin D) for at least 1 year, there was a nonsignificant trend toward a reduced incidence of vertebral (RR, 0.66; 95% CI, 0.41–1.07; 5 trials) and nonvertebral fractures (RR, 0.87; 95% CI, 0.71–1.08; 6 trials) with HT and consistent, favorable effects on BMD [ 31 ].
The group with LBW also had higher blood pressure and a nonsignificant trend toward a lower mGFR as compared with those in the NBW group.
However, the binary meta‐analysis showed a nonsignificant trend regarding the protective effect of vaccination on AMH levels.
Teglicar reduced basal insulin levels; a nonsignificant trend toward a reduction of basal blood glucose was also observed, whereas EGP, glucose infusion rate (GIR), and peripheral insulin sensitivity (GU), assessed with a hyperinsulinemic-euglycemic clamp, did not differ between treated animals and controls.
Intriguingly, although high PD-L1 seemed to be associated with RR independently of NLR, a nonsignificant trend toward better OS in patients with low NLR and high PD-L1 as compared to those with high NLR and high PD-L1 was observed.
In contrast to previous data on aromatase inhibitors, which suggested a nonsignificant trend toward increased risks of myocardial infarction and ischemic stroke in women with breast cancer, our study found that women with abdominal obesity—regardless of aromatase inhibitor treatment—had significantly higher risks of CVD and stroke alone [ 29 ].
found a higher frequency of recurrent ischemia in MVD patients at 30 days, but a nonsignificant trend toward death and major adverse cardiac events (MACE) at 30 days [ 16 ].
However, partially unlike our data, Mkhwanazi et al., (2014) have shown that the administration of a similar dose of MA could alleviate fasting hyperglycaemia with a nonsignificant trend to increase plasma insulin levels.
A nonsignificant trend towards higher rate of AF ablation at follow‐up was detected in the non‐SCV group (7 in the SCV group vs 15 in the non‐SCV group, log‐rank p‐value 0.050; Figure 5 ).
A nonsignificant trend of higher density of macrophage-like cells in MS eyes was also observed.
Mgat5 KO in the T cell–inflamed line resulted in a nonsignificant trend toward increased α-smooth muscle actin + (aSMA + ) fibroblasts ( Figure 1F ).
40 A meta‐analysis on the association between low serum magnesium and fatal CHD, which included the 2 studies discussed above, 11 , 14 found a nonsignificant trend towards an increased risk. 9 However, this meta‐analysis also included 2 studies with SCD as outcome of interest which, judging from the Forest plot, were mainly responsible for this observed inverse effect. 2 We analyzed SCD independently of CHD and found a significantly elevated risk for SCD in participants with low serum magnesium levels.
Moreover, while there was no association between concomitant use of DOACs and antiplatelet agents and the risk of all‐cause mortality among male patients (weighted HR, 0.95; 95% CI, 0.56‐1.60; I 2 , 0.00), there was a nonsignificant trend toward an increased risk among female patients (weighted HR, 1.64; 95% CI, 0.98‐2.72; I 2 , 0.00).
In addition, there was a nonsignificant trend of higher incidence of myocardial infarction in the PPI group compared to patients in the non‐PPI group (PPI group: 2.0% vs. non‐PPI group: 1.5%; OR: 1.30; 95% CI: 0.95–1.78; p = 0.096).