In addition, sodium concentrations during − 15–0, 0–30, and 30–60 min showed a nonsignificant trend toward lower values in Visit 2.
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Paradoxically, topical application of flurbiprofen sodium 0.03% demonstrated a significant increase in corneal sensitivity 30 minutes post-application while a nonsignificant trend for an increase in corneal sensitivity occurred for all other study drugs during the initial 15 to 30 minutes.
No statistical significance was detected at week 12.[ 20 ] In another study, there was a nonsignificant trend suggesting that HLA-Cw6-POS patients were more likely to respond to adalimumab.[ 21 ] In this study, it was found that HLA-Cw6 was not predictive of response to adalimumab In our study, the rate of response from infliximab in HLA-Cw6-POS patients was 75%, whereas this ratio was 77.8% in HLA-Cw6 - NEG patients ( P = 1.00).
However, a multicenter clinical trial of corticosteroids for the treatment of pulmonary fibrosis failed to show benefit, with a nonsignificant trend toward harm ( Raghu et al., 2012 ).
4 A nonsignificant trend for reduction in O 2 •− by l‐NAME in Ang II‐treated cells in our study ( Figure 2 A and 2 B) may be consistent with a partial reduction in glutathionylated heNOS‐derived O 2 •− , 4 or indicate the coexistence of other uncoupling mechanisms, such as BH4 depletion, that primarily affect the oxidase domain.
2000 ; Xu 2005 ), one found a nonsignificant trend for greater relative activity for experts ( Rhodes et al. 2004 ), and one found no difference between experts and novices ( Grill-Spector et al. 2004 ).
One found a nonsignificant trend towards improvement of self-efficacy and self-management after a coaching encounter to engage patients in a patient-owned aftercare plan [ 32 ].
In a case-control study of 40 individuals with pulmonary tuberculosis, significantly lower blood interferon (IFN) ɣ levels and a nonsignificant trend toward more severe disease were found in helminth-coinfected individuals compared with helminth uninfected controls [ 10 ].
The small sample size in the HIV− group may have limited the power to detect significant differences; however, we did find a nonsignificant trend between serum PCSK9 and MRI measures of systemic endothelial function.
In these regions, women showed a nonsignificant trend to greater increase in aggregate g ‐ratio with age as compared to men.
Mean age was 60.9 years, with a nonsignificant trend for greater age in the DOAC group (63.3 vs 56.6 years).
[ 27 ], who observed no significant differences in angiographic or clinical outcomes at two years, again with a nonsignificant trend toward better patency after balloon angioplasty.
However, various PARPi may have different cytotoxic potential and toxic side effects on tumor cells owing to their different ability to induce PARP reverse conformation, which makes the OS outcome of patients with BC show considerable variability: whereas EMBRACA and BROCADE3 reported statistically significant OS improvements, OlympiAD revealed only a nonsignificant trend toward OS benefit.
Interestingly, late follicular and ovulatory phase initiations were associated with significantly higher estradiol and LH levels at S8, with a nonsignificant trend toward higher oocyte retrievals.
On the other hand, survival analysis within the metastatic cohort suggested a nonsignificant trend toward longer survival in the high-expression group.
Additionally, there was a nonsignificant trend of a higher density of monocytes/macrophages, a higher collagen volume fraction, and a higher viral load ( p -value 0.154, 0.186, and 0.402 respectively).
Furthermore, there was a nonsignificant trend toward higher turbidity for treatments with fish and unmanipulated crayfish than for those with unmanipulated crayfish alone (Cohen's d FUMvsUM = 0.42, CI95% FUMvsUM = [−0.03; 0.81]; Figure 2 ; Table 1 ).
For instance, the KORA F4 study found a nonsignificant trend suggesting a positive association between higher PAC levels and cardiovascular mortality, stroke, and composite cardiovascular endpoints, but not with MI 30 .
Within the fibrin glue group, there was a nonsignificant trend toward a higher incidence of diabetes compared with the control group ( Table 1 ).
There was a nonsignificant trend for long-duration exercise to increase plantaris muscle COXIV activity ( Figure 1C ).
We note, however, that our data show a nonsignificant trend where larger groups exhibited smaller learning gains ( Table 4 and Figure 12 ), and this is also apparent in the normalized gains: the normalized gain was 44.0% for two-person groups, 37.3% for three-person groups, 37.5% for four-person groups, 31.7% for five-person groups, and 15.4% for six-person groups.
25 Shown in Table 4 , in this cohort of patients with mild stroke or TIA, the reasons for readmission were most commonly cerebrovascular, followed by cardiopulmonary circulatory diagnoses, with a nonsignificant trend for more frequent ICD‐10 codes representing these conditions in the INV arm compared with UC.
In our hands, extracellular addition of C3a did not make statistically significant changes in cell survival, although there was a nonsignificant trend toward improved survival of C3 −/− clones ( Fig. 3 B ) up to 100 nM C3a, levels which are unlikely to be achieved in vivo, where C3a is rapidly inactivated by serum carboxypeptidase N ( 44 ).
A nonsignificant trend toward lower 25(OH) vitamin D levels at admission was observed in patients who required NIMV compared with those without (11.9 [8.2-18.9] ng/mL vs 15.8 [10.8-25.5] ng/mL; P = .077).
Association between waist circumference and metabolic syndrome components The result of the meta regression showed that the decrease in WC was significantly associated with decrease in LDL, SBP, DBP, FBS, and TG and a significant increase in HDL but a nonsignificant trend was found for the association of WC with TC [ Table 2 ].