“a nonsignificant trend”

10 In contrast, another study identified enterocele as a risk factor for worse symptomatic outcomes after stapled transanal rectal resection for obstructed defecation, with a nonsignificant trend toward recurrent rectal intussusception. 27 We propose that an enterocele may predispose to recurrence through a number of mechanisms.

In the largest desensitization study to date, patients with recurrent ovarian cancer receiving carboplatin via desensitization had a nonsignificant trend toward increased life expectancy compared to matched controls receiving standard infusion, suggesting that at the least there is no trade-off in terms of mortality [ 31 ].

12 , 13 , 21 – 23 Within the time frame we examined, small sample sizes (<50 patients; n = 75 studies) and a high proportion of single-center trials (86.3%) were observed, and there was a nonsignificant trend toward smaller mean sample sizes over time (see Table 2 ).

3.0%; RR 0.56; 95% CI 0.35–0.87), with a nonsignificant trend toward reduced use of RRT.

Clinical pregnancy rates showed a nonsignificant trend toward more multiple gestations in the agonist group.

Hepatocyte growth factor therapy showed a nonsignificant trend towards pain reduction, and prostaglandin infusion demonstrated no meaningful effect; both excluded large proportions of the CLTI cohort.

When the compound trans - 1 was incubated at 0.2, 2, and 20 μM, the levels of sma-miR-10-5p in the worms and supernatant showed a nonsignificant trend of decreasing by up to 20% with an increase in concentration after 96 h ( Figure S3 ).

As previously described with high RV pacing burden, 3 we also observed a nonsignificant trend toward LV and RV functional decline and a significant increase in moderate-to-severe mitral valve regurgitation (n = 6 [19%] vs 27 [90%]; P < .001).

Consistent with findings from the ITT analysis, a nonsignificant trend toward a reduced risk estimate was observed for the composite CVD and new HF or CM diagnosis.

The anhepatic time showed a nonsignificant trend toward prolongation ( Table S1, SDC , https://links.lww.com/TXD/A883 ).

Most ether lipids measured display mean levels that increase with phenformin treatment, though these changes are either nominally significant or exhibit a nonsignificant trend because of the strict threshold required to reach significance when correcting for multiple hypotheses.

This is similar to the findings of our study, which found a nonsignificant trend of improved IGFBP-3 levels after exercise.

Univariate analysis to identify risk factors for false-negative events showed that the early study period and institution had a nonsignificant trend.

A nonsignificant trend was observed whereby some isolates with more growth in vehicle-treated mice required higher fAUC/MIC ratios for efficacy ( Fig. 2 ).

In contrast, ctDNA changes were not associated with OS at any time point although a nonsignificant trend suggested that any decrease of ctDNA from day 8 onward was associated with better OS.

Moreover, at a lower concentration of U0126 (5 μM), a nonsignificant trend toward ZEB2 upregulation was noticed in the PC9-GR cell line.

Finally, for the PedsQL GCS total score, there was a nonsignificant trend for QoL to be lower in children (mean 44.1, SD 16.7) than adults (mean 46.4, SD 12.3).

In contrast, TCDDHFD islets showed a nonsignificant trend toward having only ~2-fold higher Cyp1a1 compared to COChow islets, and Cyp1a1 levels remained significantly lower than in TCDDChow islets ( Fig. 6B ).

Perfluorooctane sulfonate, on the other hand, increased significantly over the entire monitoring period, whereas the trend analysis starting in the same year as PFOS production started to decline (2000) revealed a nonsignificant trend only, possibly indicating the start of declining concentrations.

There was only a nonsignificant trend in the pharmacokinetics of these anesthetics favoring mepivacaine.

It is interesting that BIN1 showed a nonsignificant trend for association in the previous studies by Harold et al. and Lambert et al.

After adjusting for all variables, higher FT4 was independently correlated with an elevated risk of CVD, while a higher FT3/FT4 ratio was independently correlated with a decreased risk of CVD, with a nonsignificant trend toward a lower CVD risk for FT3.

31 A more recent multicenter randomized, double-blind, placebo-controlled pilot trial from the Parkinson Study Group POETRY Investigators showed a nonsignificant trend of symptomatic and functional improvement in those receiving ERT. 32 Concerning the small number of participants included in each original study, it is conceivable that the conflicting results were due to the small sample size.

However, there was also a nonsignificant trend for stronger associations between KAP and self-reported total sleep period when the participants used the keyboard during more hours on the previous day.

Patients with both high CD47tumor_score and positive PD‐L1_TPS showed a nonsignificant trend toward worse PFS and OS compared to all other patients.