Using Cox proportional hazards models with asenapine as reference, quetiapine demonstrated a significantly lower hazard of achieving calming (hazard ratio 0.39), while risperidone showed a nonsignificant trend.
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In sensitivity analyses, there was a nonsignificant trend for a benefit of AmB + 5FC over AmB alone among studies that included participants with altered consciousness, but we found no other subgroups for which combination therapy seemed to be of benefit ( Supplementary Table S3 ).
Prior work showed that severely damaging SDHB truncating alleles were associated with increased risk of PPGL, while missense variants exhibited a nonsignificant trend toward increased risk of hnPGL ( 44 ).
Similarly, in Blichert-Toft's study of mastectomy versus breast-conserving surgery for breast cancer [ 30 ], randomized patients were more likely than nonrandomized patients to experience the outcome of cancer recurrence (13.7% versus 6.6%), although the difference was of borderline significance (relative risk: 2.08; 95% CI: 1.07, 4.02). In the single study in which randomized patients were categorized as having a better baseline health status than nonrandomized patients, there was a nonsignificant trend towards the randomized patients being less likely to experience disease recurrence or death (odds ratio for randomized versus nonrandomized: 0.35; 95% CI: 0.12, 1.01) [ 31 ].
A nonsignificant trend toward an increase in baseline fluorescence was also observed at all concentrations of oxotremorine ( Fig. 7 D ).
This non-parametric test yielded a chi-squared statistic of χ 2 = 3.33 ( p = 0.068), indicating a nonsignificant trend toward higher gene discovery rates in Gram-negative species.
We found a nonsignificant trend towards a greater effect of familiarity for inverted faces: 51 ms [26, 77] for upright faces, and 83 ms [50, 116] for inverted faces (difference 33 ms [–10, 74]).
One explanation may be lack of power, as there was still a nonsignificant trend toward worse CPP in those with cyclic CHC ineffectiveness.
Although there were significant increases in Bglap expression in the LPS-stimulated cultures following parecoxib treatment, a nonsignificant trend towards a decrease was also noted in unstimulated cultures ( Figure 4(f) ).
We investigated the contribution of PHE interactions with an analysis correlating A1c values to number of touchpoints and observed a nonsignificant trend towards correlation between these factors.
Among patients without gastrointestinal symptoms, there was a nonsignificant trend toward elevated VAT/SAT ratio in those who died, which was not seen in patients with gastrointestinal symptoms.
However, we found a nonsignificant trend towards a reduced risk of all-cause mortality, ischemic S/SE and net clinical outcome between edoxaban 60 mg daily and warfarin.
While the ACE index showed a nonsignificant trend in α-diversity (Fig. 1 C), β-diversity assessed by principal coordinates analysis (PCoA) based on UniFrac distance revealed significant separation between the OVX and Sham groups ( P = 0.005) (Fig. 1 D).
The HR for adjuvant nivolumab shifted from above one in the univariable analysis to below one after adjustment for ypT and ypN (HR 0.602 [0.240–1.511], P = 0.280), suggesting a nonsignificant trend toward reduced DFS risk.
One week after treatment, the ORS-treated group showed a nonsignificant trend toward a lower SBP (194.1 ± 18.3 mmHg) relative to control (209.0 ± 7.8 mmHg).
Middle deltoid and biceps brachii activities increased significantly, with a nonsignificant trend toward higher upper trapezius activation.
In patients younger than 80 years (mRS 0–2: aOR, 1.52; 0.84–2.77; p = 0.166) and without stroke history (aOR, 1.60; 0.85–3.06; p = 0.152), tenecteplase therapy was associated with a nonsignificant trend toward better functional outcomes at 90 days.
In the landmark analysis, time‐to‐event demonstrated a nonsignificant trend toward lower MACE with IVL, suggesting that early events within 30 days may have driven the overall hazard difference (Supporting Information S1: Figure 4 ).
The radial and circumferential function remained unchanged during follow-up; however, a nonsignificant trend of an increase after transplantation was observed.
Electrophysiologically, there was a nonsignificant trend toward b-wave and oscillatory potential (OP) preservation in the trabodenoson-treated eyes.
In fact, the manual capsulotomy group showed a nonsignificant trend toward greater circularity compared to the FSL group. 30 In regards to capsulotomy strength, Friedman et al . and Nagy et al ., showed greater strength in FSL-guided capsulotomies in porcine eyes. 12 , 31 Summaries of all reported capsulorhexis parameter studies allow for direct comparison [Tables 1 – 3 ].
Delayed patients had 50% higher mortality (HR: 1.50), 59% higher risk of HF hospitalizations (HR: 1.59), and a nonsignificant trend toward higher risk of disabling stroke (HR: 1.25), and incurred $36,740 in additional health care costs over the 3-year follow-up period.
Conversely, in a untreated 7 mm calvarial defect created 4 weeks post-OVX, there was a nonsignificant trend for higher bone volume within the defect space of OVX rats compared to rats receiving sham OVX[ 13 ].
In colonic biopsy tissues from UC patients, a nonsignificant trend towards reducing the activity of mitochondrial electron transport chain complex I and complex II is observed [ 17 ].
A nonsignificant trend was found when examining differences between Arabs and Jews in prevalence of weight stigma experiences, suggesting that weight stigma experiences may be slightly more common among Jews relative to Arabs.