There was a nonsignificant trend towards a decreased frequency of spontaneous contraction with advancing age (change in contraction frequency for a 5-y increase in age = −26.4%, 95% CI, −50.9% to 10.2%, p = 0.14).
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The meta-analysis revealed a nonsignificant trend for poorer CSS among CRCs harboring BRAF mutation ( Figure S2 ).
[ 60 ] also reported that the β-lactam-resistant phenotypes were more frequent in infants who received one or more antibiotic therapies, although with a nonsignificant trend.
In contrast, the incidence of acute and late genitourinary (GU) toxicities was higher after LDR-BT boost, and there was a nonsignificant trend for worse gastrointestinal (GI) morbidity 5 .
A small trend to a smaller decline in the spine bone mineral density over 10 years in postmenopausal women using opioids, in comparison to non-exposed, was demonstrated (however with a nonsignificant trend towards more fractures) in Danish Osteoporosis Prevention Study (Vestergaard et al. 2012 ).
In a crossover trial in which 30 patients with T2DM and coronary artery disease received 12-week courses of liraglutide and placebo in random sequence, insulin clearance did not differ between the interventions, though there was a nonsignificant trend towards higher clearance with liraglutide in completer analyses consisting of only 73% of 41 randomized participants [ 9 ].
However, both lin-35 ( n745 ) and lin-54 ( n2231 ) mutants did show a nonsignificant trend toward fewer oocytes when upshifted to 26 °C compared with the same strain at 20 °C ( Fig. 4a ).
The male AIR group also showed a nonsignificant trend toward more entries into the zone surrounding the novel mouse compared to entries of the ISO males (Fig. 3H ; Table 3 ).
7e ), we also observed a nonsignificant trend toward the suppression of reactive oxygen species and UV-response gene sets (Fig. 7e ), suggesting reduced oxidative stress, as also observed in patient-derived TAMs.
As we observed with microinjections into the BST, injection of nor-BNI plus U50 into the MPA was associated with a nonsignificant trend toward increase in UNaV.
However, mean IKDC improvement was 42.2 points in MB versus 39.7 in FB, and Kujala improvement was 42.4 versus 41.8, suggesting a nonsignificant trend favoring MB implants in patient-reported outcomes ( Table 3 ).
There was also a nonsignificant trend for MUC5B to have a reduced mRNA level in the presence of the moderate-to-severe asthma risk allele.
Although this P -value suggests a nonsignificant trend that warrants cautious interpretation, the adjusted OR of 1.54 (95% CI: 0.95–2.50) indicates that a clinically meaningful association cannot be definitively excluded with the present sample size.
There was a nonsignificant trend towards improved outcome in patients with high EGFR expression compared with low EGFR expression (TTP 5.1 months versus 1.8 months and OS 7.8 months versus 2.8 months). 73 In all the trials of oral TKIs as monotherapy or combination therapy, there has been no significant additional toxicity associated with the use of TKIs.
Furthermore, information about the protocol for the review was associated with a nonsignificantly lower number of ‘No’ answers in univariate analysis and a nonsignificant trend in multivariable analysis.
Conversely, anticoagulant therapy was associated with a nonsignificant trend toward an increased risk of major bleeding (relative risk, 1.19; 95% confidence interval, 0.85–1.66; I 2 = 13.5%).
Our data demonstrated that berberine with a minimal oral administration dose of 1.2 g/day had a nonsignificant trend toward higher proportion of SR during the one-year follow-up when compared with amiodarone ( Figure 2 ).
The FOxTROT trial demonstrated a significant decrease in the R1 resection rate and a nonsignificant trend toward better oncological outcomes at 2 years. 14 However, only a few patients in the FOxTROT trial had colonic obstructions (2.7%).
Furthermore, we used IAV as a primary stimulus and total RNA from T4R as the secondary stimulus, but we could only observe a nonsignificant trend to increased IL-12p70 production relative to bacterial RNA alone (see Fig.
Haptoglobin levels did not significantly correlate with lesion number overall (r = 0.00; P = .975), although a nonsignificant trend toward reduced haptoglobin was noted in the ≥50 lesion group.
Although the numerical increase from 91.8% to 100% was not statistically significant (χ2 = 2.60, p = 0.107), it is reported as a nonsignificant trend rather than a definitive effect.
Effect of standard antiarrhythmic strategies Among those patients in whom a single antiarrhythmic therapy was initiated or added and where multiple rhythm monitors were available, there was no difference in subsequent control of AF burden across time (Supplemental Table 6A ); there was a nonsignificant trend toward reduction in those managed with the addition of ≥2 antiarrhythmics.
[ 20 ] ( Table 3 ) showed a nonsignificant trend towards improved complete control of nausea (50% versus 38% with placebo) and vomiting (78% versus 71%) (i.e., primary end point was not reached).
In our work a nonsignificant trend toward better LPFS with a lower EDIC and no clear improvement in PFS was observed.
There was a nonsignificant trend of increase in author number and also a nonsignificant decrease in the percentage of review, clinical trials and editorial articles of duplicate publication between the two groups of years.