Although we only observed 11 patients with MDR TB and diabetes, we found a nonsignificant trend toward an increased median time to sputum culture conversion among MDR TB patients with diabetes.
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Results also showed a nonsignificant trend toward better performance in the incongruent trials of the Flanker Squared Task, an effect that was mediated by reduced perceived exertion. status released display-pdf yes is-in-collection-domain yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Revised 2025 Jun 23; Received 2025 May 14; Accepted 2025 Jul 16; Issue date 2025 Oct. 1.
Although reduction of pain and REU had a nonsignificant trend favoring triamcinolone acetonide in this study, they showed that PRF could be a potentially safer alternative for corticosteroids.
In the majority of available surveys, insulin therapy was actually associated with significantly increased risk of cancer [ 31 – 39 ] or a nonsignificant trend toward an increased incidence of malignancies [ 40 – 43 ].
53 In addition, rest breaks were found to be protective against severe increases in creatinine and a nonsignificant trend that increasing USG was associated with increases in creatinine.
The relationship between CPAP adherence and health literacy has been evaluated in only two trials, in which health literacy was a secondary outcome; one found a nonsignificant trend toward poor adherence with low health literacy, and the other found no significant relationship [ 8 , 17 ].
Notably, a recent meta-analysis of melatonin in CABG patients found only a nonsignificant trend toward lower CK-MB with melatonin [ 14 ], consistent with our results.
Among those with positive PD‐L1 expression (TC1/2/3 or IC1/2/3) treated with atezolizumab, an elevated pretreatment LDH level was associated with a nonsignificant trend of worse PFS and OS; this likely reflected the small patient numbers.
Pravastatin was associated with improved OS (HR: 0.674, 95% CI: 0.471–0.964) but showed a nonsignificant trend toward improvement in DFS (HR: 0.742, 95% CI: 0.532–1.037) [ Table 2 ].
Maternal smoking during pregnancy inferred a nonsignificant trend for SUDEP risk (OR 1.79; 95% CI .93–3.43).
2 , 10 The reason this was not found could be due to the small sample size, as a nonsignificant trend towards increased medication discrepancies in regular medications with longer stay was observed.
In the entire cohort, CD8 + T-cell density showed a nonsignificant trend toward reduction in TTF-1-negative tumors.
The other species were not significantly different (and Anas clypeata even showed a nonsignificant trend of increased alpha diversity in IAV + individuals, Fig. 3B ).
Females showed a slightly lower baseline of proliferation and a nonsignificant trend toward reduction with LPS.
However, patients with low CMAP amplitudes of the tibial nerve ( Table 2 ) did show a nonsignificant trend towards a higher ODSS and a longer disease duration than patients with higher amplitudes, and also had significantly increased proximal CSA-HRUS-MRN values of the tibial nerve as well as significantly decreased FA in proximal nerve segments.
While only a nonsignificant trend towards better OS was observed with surgery, we found that DFS was significantly longer in resected patients.
Additionally, vitamin B12 showed a nonsignificant trend in reducing contrast surround suppression [ 218 ], and vitamin B12 is associated with GABA increase and glutamate decrease in animal models [ 234 ].
A nonsignificant trend for decreasing AMH with BMI was also observed. 10 Our results are concordant with these findings suggesting that lower AMH may be a marker of obesity and metabolic dysfunction.
The attenuation of this association to a nonsignificant trend in the female-only model may reflect reduced statistical power or genuinely weaker effect in female patients, warranting further investigation.
However, the reverse method showed a nonsignificant trend toward lower PCR.
8 French study reported a high early mortality rate of 32% among 31 patients with PPFE, with a nonsignificant trend toward higher early mortality in those with a flat chest compared with those without (70% vs. 48%). 9 These findings further support the potential benefit for performing LT before chest flattening becomes advanced.
81 However, the clinical significance of this finding remains unclear, as there was only a nonsignificant trend toward an increased prevalence of assay-defined B12D in the lithium group at 1 center, and no cases at the other center. 81 Additionally, a statistically significant direct association was reported between hair lithium and cobalt concentrations, suggesting a role of lithium in the transport and distribution of vitamin B 12 . 82 This interaction may contribute to the observed decrease in serum B 12 levels in patients on lithium therapy.
hHSPB1-overexpressing mice showed enhanced expression of pro-inflammatory cytokines Tnf and Il1b as well as increased immunoreactivity of astrocyte and microglial activation markers in response to ethanol-induced acute brain injury, whereas they exhibited a nonsignificant trend of decreased apoptosis.
Singh et al found a significant negative impact of Black race on LOS and a nonsignificant trend of Black patient discharge to rehabilitation facilities.
The meta‐analysis indicated a nonsignificant trend towards reduced all‐cause mortality in KT patients with hypophosphatemia.