Other than a nonsignificant trend towards decreased modulated vSMCs with TMAO feeding, the single-cell distribution from HC+TMAO versus HC mice was similar (Figure 1 H; Table S2 ).
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There was a nonsignificant trend toward an increasing Christmas holiday effect in the later time periods, suggesting against any attenuation of the size of the Christmas effect (Table S3).
Mutation of other genes, including KIT , PHF6 , TP53 , RUNX1 , TET2 , ASXL1 , and FLT3 ‐ITD, were associated with a nonsignificant trend of reduced OS, whereas mutation of several genes, including CEBPA double mutation , IDH1 , IDH2 , and NPM1 were trended to correlate with a prolonged survival (Table 1 ).
However, within the QQ genotype, we found a nonsignificant trend, with Caucasians having a higher mean DZOase activity than African Americans.
35 In our study, atrial fibrosis showed a nonsignificant trend toward an increase in aged rabbits and human AF samples ( Supplemental Figures 1 and 2 ), consistent with high interindividual variability.
Quantitative IHC analysis revealed significant 2.2- and 3.0-fold increases in retinal NGSDMD and CCasp3 signals, respectively, in AD versus normal-cognition controls ( p < 0.001–0.0001), whereas MCI retinas exhibited a nonsignificant trend toward elevation (Fig. 4G , I).
The summary risk ratio for contrast-induced nephropathy was 0.68 (95% CI, 0.46 to 1.02), a nonsignificant trend towards benefit in patients treated with intravenous NAC.
Finally, we observed a nonsignificant trend of NF-κB pathway-activating mutagenic events in patients with TNFRSF17 biallelic loss or mutations, with three out of the six patients harboring clonal TRAF3 or CYLD or MAP3K14 biallelic deletion or SNVs (Supplementary Fig. 7 ).
A strong association between closure devices and major bleeding was established using unadjusted regression and propensity‐matched methods, with a nonsignificant trend also demonstrated with adjusted regression.
A recent Indian study has demonstrated significant improvement in the quality of life and a nonsignificant trend toward improvement in glycemic control of diabetic patients practicing the comprehensive yogic breathing program.[ 9 ] Yet another study from India showed that cardiac autonomic functions improved in patients with diabetes who followed the comprehensive yogic breathing program.[ 10 ] Another study showed that 8-week yoga intervention was feasible and resulted in greater weight loss, reduction in waist circumference and psychological well-being when compared to a walking control.[ 11 ] Thus, evidence for benefit of yoga is becoming more robust.
By comparison, there was a nonsignificant trend for increased median survival with ILF in this study (10.8 months) and this compares well with data reported for more recent exploratory combinations such as capecitabine and docetaxel (10.5 months), and epirubicin, docetaxel and cisplatin (11.0 months) ( Lee et al , 2004 ; Park et al , 2004 ).
In case of macrometastatic disease, there was a nonsignificant trend toward better outcomes in axillary recurrences and survival after cALND, but only after analysis was adjusted for clinicopathologic differences. 10 In the ACOSOG Z0011 trial, Giuliano et al. 65 observed no differences in overall survival between the cALND arm and the arm in which cALND was not performed.
There was a nonsignificant trend for faster reactions of CB (296 ± 36 ms) compared with SC (315 ± 24 ms) in response to right index finger stimulation.
Although the former identified a nonsignificant trend toward increased weight in group‐MD but not in group‐RD, RM‐ANOVA results indicated statistically significant changes in weight between D0 and D60, independent on the diet administered.
In early-stage patients, low EpAb3-5-assessed EpCAM expression was significantly associated with improved OS in most early-stage subgroup analyses (Figure 3 A, 3C, and 3D), whereas only a nonsignificant trend was observed in node-negative patients (Figure 3 B).
Surprisingly, 11 (OP-lysine) was present already in raw meat with 22.8 μg/kg protein and only gave a nonsignificant trend to 24.2 μg/kg when heated.
1 (F and G) , it is apparent that the onset of neutrophil recruitment is independent of dose, while the rate of recruitment may be dose dependent at later time points, which is seen as a nonsignificant trend in the respective 90-min data.
The rest of the morbidities did not show significant gender differences between years, although a nonsignificant trend toward a decrease or dilution of the gap could be observed in high cholesterol and high blood pressure. 3.3.
Further, it demonstrated a nonsignificant trend towards reducing the blood transfusion rate.
The risk increased with the severity of the TBI and showed a nonsignificant trend towards a stronger association between AD and TBI in men with ApoEε4 alleles [ 9 ].
Comparing older (age > 30 years; n = 20) and younger volunteers revealed a nonsignificant trend towards reduction in cerebrovascular reactivity (difference 0.07; 95% CI: −0.25 to 0.13) between the groups.
mutans was recorded, but a nonsignificant trend was seen for Lactobacilli.
Amongst patients with low-risk disease (defined as a PSA <10 ng ml −1 and Gleason <7), there was a significant reduction in both all-cause mortality and distant recurrence with RP and a nonsignificant trend towards reduction in prostate-cancer related mortality.
Blanco et al found a strong correlation between the stimulated salivary function and the QOL scores 6 months after RT and a nonsignificant trend towards improvement in the mean QOL scores between 6 and 12 months [ 5 ].
Leukemia development was monitored monthly by analyzing CD5 + CD19 + cells in the PB of CD49dΔB TCL1-tg mice and TCL1-tg littermates, with a nonsignificant trend of higher leukocytosis at months 5, 6, 9, and 10 in the CD49dΔB TCL1-tg model ( Figure 1 B).