In six children with severe physical sequelae and their parents, there was a nonsignificant trend towards more psychological symptoms at follow-up [ 26 ].
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Besides a nonsignificant trend for an increase in REST in transgenic mice, we evaluated the potential effect of a mutated TARDBP overexpression in well-established REST targets by RT-qPCR.
We found that gut microbial diversity was reduced in IBD patients compared with healthy controls, with a nonsignificant trend toward a greater reduction of diversity in UC patients than in CD patients.
In both of the studies, there was a nonsignificant trend toward higher all-cause mortality in the CR intervention group compared with the usual care group (Figure not shown).
There was a nonsignificant trend toward higher successful introduction rate if pasteurized milk was used as test material compared to milk protein powder, and condensed milk.
A nonsignificant trend of decreasing rSO 2 with increasing ketamine infusion was noted.
A nonsignificant trend for improvement was seen in other timing measures, including PTT.
There was, however, no reliable difference in the N2pc amplitudes or latencies between the two cue conditions, although there was a nonsignificant trend for target-color cues to evoke a slightly larger and earlier N2pc than irrelevant-color cues.
In contrast, pooled analyses found no clear association between comorbidity burden and PFS (pooled HR 1.00, 95% CI 0.89-1.14) and only a nonsignificant trend toward more treatment-related AEs in high-CCI groups (pooled HR 1.73, 95% CI 0.79-3.79).
There was a nonsignificant trend for higher odds of cessation in the intervention group compared with the control group.
Controlled trials of rituximab are limited to a single phase II trial in RRMS in which magnetic resonance imaging (MRI) activity at 6 months after a single dose was the primary end point, and in PPMS, a single phase II/III trial revealed a nonsignificant trend for reduced CDP.
The pretreatment group showed a nonsignificant trend of decreased GFAP expression compared with that of the treatment group ( FIGURE 3B ).
However, the MITLIF group showed a nonsignificant trend toward a decreased risk of ASD compared with the OTLIF group, suggesting that MITLIF may be associated with lower long-term morbidity compared with OTLIF [ 20 ].
Outcomes for the 192 patients with proven p16-positive disease according to RPLN status are shown in Figure 2 , with a nonsignificant trend for inferior outcomes for p16-positive patients with involved RPLN compared to those without.
We observed a nonsignificant trend toward increased CD4/CD8 ratios in untreated RRMS patients, which was completely normalized within (but not below) physiological (HD) range in Dac-HYP cohort.
Mortality was greater in levosimendan than in placebo subjects, but there was a nonsignificant trend to improved survival compared to dobutamine subjects (8) .
Increased expression of translocase of outer mitochondrial membrane 20 was associated with a nonsignificant trend toward better prognosis, and increased expression of MCT1 was associated with a better outcome.
Consistent with the first possibility, we observed that there was a nonsignificant trend toward larger changes after mMAN lesion for transitions with low history dependence ( Figure 2—figure supplement 5B ).
Although CHIP carriers in the placebo arm exhibited only a nonsignificant trend toward increased major adverse cardiovascular events (MACE), patients harboring TET2-mutant CHIP derived substantial benefit from IL-1β inhibition with canakinumab [ 23 ].
There was also a nonsignificant trend for greater expression of these proinflammatory cytokines in cells from diabetic compared with tolerant mice.
Interestingly, while prior antibiotic use showed a nonsignificant trend toward poorer outcomes (HR = 1.44; 95% CI = 0.90–2.31), it did not reach statistical significance in this model.
having previously diagnosed diabetes and poor glucose control (HbA1c ≥ 7.0) had significantly higher rate of rapid CACs progression over annual change of > 30% of baseline score (OR:2.3, 95% CI:1.4–23.7) compared to reference group of patients having no previous DM history and HbA1c < 5.7% yet only a nonsignificant trend of increased risk for participants with well controlled known diabetes history (HbA1c < 7.0%), similarly according to fully-adjusted linear regression model % change in geometric mean of PF5 (Progression Factor at 5‘th Year Examination), which is extrapolation of exponential model derived on age an
Apixaban patients had a nonsignificant trend toward a lower risk of hemorrhagic stroke (HR: 0.77, 95% CI: 0.53–1.13) compared with warfarin patients ( Fig 2B ).
Our findings suggest that depressive symptoms showed a nonsignificant trend toward increased risk of incident cancer in middle-aged and older Chinese adults.
However, the estimates for mortality are modified (RR 0.92, 95% CI 0.83–1.02, p=0.098; I 2 =0%) ( figure 2 ), suggesting a nonsignificant trend towards lower mortality in patients randomised to SSD.