“a mild trend”

3 ), although a mild trend was observed.

Earlier studies also reported possible negative outcome after DBS for semantic and phonematic verbal fluency and a mild trend for a deterioration of verbal memory (Foki et al. 2017 , Foki et al. 2018 , Harati et al. 2013 ).

We agree that this is a very interesting question, and we have now performed various additional studies to explore the role of nAchR signaling in ISC to EE differentiation: – To confirm our nAchR α2 MARCM data, we utilized the esgF/O strategy (Jiang et al., 2009) to knock down the expression of other subunits in clones via RNAi and observed a mild trend towards fewer EEs in α2 and α4 knockdowns (Figure 2 —figure supplement 2F).

When HGSOC were stratified to stage a mild trend of augmented RANK expression, an increasing stage was observed, but no significant differences were detected ( Figure 2 C). 2.1.2.

A mild trend to have a higher rate of hypovitaminosis D (81,3% vs 68,3%), arthralgia (47% vs 32%), GERD (66% vs 52%), ILD (36% vs 27%), anti CCp positive (12% vs 7%), electrocardiogram abnormalities (19% vs 10%) and PAH (50% vs 32%) was observed in pts-SSc with nRAD compared to those without.

Global longitudinal strain (GLS) of the left ventricle did not show statistically significant changes in response to either pacing strategy ( p = 0.212), although a mild trend toward improvement was noted following biventricular pacing.

TGF-β showed a mild trend of increased expression at early time points whereas BMP-2 rose steadily throughout the investigated 8 weeks of healing, thus paralleling the observed increase in bone formation.

Interestingly, BAY treatment promoted a relative decrease in weight of the fast-twitch extensor digitorum longus (EDL) and a mild trend for decreasing the weight of the quadriceps ( Figure 2, G and H ).

A mild trend for larger amplification in slow frequency power is shown for network size > 200.

While not statistically significant, there was a mild trend toward higher MPOD levels in subjects who reported no difficulty driving at night (0.47 ± 0.18 DU) than in those who reported at least a little difficulty (0.39 ± 0.13 DU; 0.10; t [21] = 1.229, p = 0.116).

Using a difference plot, a mild trend of differences was proportional to the measurement's magnitude.

Notably, while this group exhibited a mild trend toward reduced inflammation, the effect did not reach statistical significance.

We observed only a mild trend toward reduction in the frequency of apoptosis in HSPC subsets in Tet2 -KO relative to WT mice (Supplementary Fig. 7a ).

Right ventricle hypertrophy (measured by Fulton index) showed only a mild trend of increase in both males and females without reaching statistical significance (Fig. 1 b).

Hypertension showed a mild trend in non-paroxysmal AF [OR 1.63 (95% CI 1.22–2.18)] but none in paroxysmal AF [OR 0.95 (95% CI 0.42–2.11)], though the subgroup difference was not significant ( P = 0.21) (see Supplementary material online , Figure S5A ).

Analysis of EM sections revealed a mild trend of reduced nuclear-mitochondrial membrane contact sites in the untreated parasites compared with the iTgNup503 line; however, no change in the abundance of the nuclear mitochondrial membrane contact sites following TgNup134 depletion was seen ( Fig. 5 E ) in support of the specificity of the observed reduction upon TgNup503 depletion.

And although a mild trend towards improvement in some dysphagia domains was evident, we found neither a statistically significant nor clinical meaningful impact.

There was a mild trend towards less inflammatory response in implanted App NL−G−F mice compared to implanted WT.

Intriguingly, 8-m-old male Lmna f/f ;AC mice exhibited a mild trend toward reduced average adipocyte size at room temperature (RT) (Fig. 4e ), accompanied by reduced mRNA levels of Ucp1 , Pgc1a , and Pparg in iWAT (Fig. 4g ).

In addition, it is important to note that the large size of the whale RGCs were between 26.5 and 112.9 μm in diameter, with an average size of 52.5 μm in the center and 65.3 μm in the periphery of the retina, reflecting a mild trend in the increase of the soma size toward periphery.

However, a mild trend toward reduced satisfaction was observed among those with persistent numbness.

A mild trend towards increased overlap of both structures after combined application of both drugs suggested mild additive or synergistic BCL-2 pathway-mediated anti-apoptotic signaling.

Chemotherapy had no measurable impact, and radiotherapy showed only a mild trend toward poorer aesthetic scores.

There was no significant difference between night and day exposure levels, despite a mild trend for less noise during the night shift.

The major complication rate shows a mild trend of increase in the third stage, which may be caused by the new participants of the second and third operators.