“a marked trend”

Consequently, we can conclude that with the continuous progress and development of DIG, the value of the older adults care industry exhibits a marked trend of growth.

Moreover, the small sample, which did not even contain all types of B3 lesions, made it difficult to obtain statistically significant results, especially in the analysis of histological types of B3 lesions, where we observed a marked trend toward upgrade in ADH lesions.

Table 2 shows that the modularity index of the GIOTN underwent phased changes from 2000 to 2023: it rose gradually from 0.30 in 2000–2006 to 0.49, indicating strengthened intra‐community ties and weakened inter‐community links, with early signs of regional clustering; declined progressively to 0.06 in 2006–2014, reflecting enhanced inter‐community connectivity and greater trade network integration; peaked at 0.50 in 2015, when the network split into multiple highly autonomous trade communities, underscoring a marked trend toward regional cooperation; fell back to 0.08 in 2015–2020 as inter‐community links intensified and the network reintegrated, demonstrating the resilience of globalization; and rose again in 2021–2023, signaling stronger intra‐regional cluster connectivity in the post‐pandemic era and the reemergence of regional cooperation as a dominant feature.

Assessments grounded in cognitive and neurophysiological methodologies reveal that executive function, though initially emerging during the foundational years of life, exhibits a marked trend of continual strengthening and maturation throughout childhood and adolescence [ 50 ].

The study by Revol [ 88 ] evidences a marked trend to anxiety disorders in a population of early developers consulting in child psychiatry, observing phobias, and even obsessive-compulsive disorders. 5.

The remarkable changes that have occurred in dietary habits throughout past centuries are mostly characterized by a shift towards a sodium-rich diet (i.e., a potassium-to-sodium intake ratio usually < 0.4), and have also been associated with a marked trend towards sodium overload and potassium depletion 17 with significant adverse cardiovascular effects 18 .

There was a marked trend towards decreased mesothelin concentration with the progression of the disease.

There was a marked trend towards a higher tumour incidence in Limk2-KO mice ( figure 9 F).

In addition, all skin quality parameters assessed by the investigator and subjects showed a marked trend of improvement from baseline to week 12 (Figure 9 ).

The high densities of TILs, high ratios of PD-1+/CD8+ cells, and high levels of PD-L1 have been suggested that are negatively associated with melanoma brain metastases size, and high levels of PD-L1 may support a marked trend towards better survival [ 33 ].

We observed a marked trend towards decreased Gcg mRNA expression in the colon of HFD-fed mice, its major expression site (Fig.

Significant differences for group and time were obtained for total cholesterol ( Figure 6 a) and a marked trend for an interaction of group–time was also observed.

Although this reduction was not statistically significant in BxPC-3 cells, there was a marked trend toward a decrease at the G2-phase cell percentage as well.

We observed a marked trend of development of apps oriented toward the Android platform (63%), which can be associated with the popularity and assortment of mobile devices (cell phones and tablets) for this platform.

However, besides the expected unlimited freedom to rotate of CAN in solution, there is a marked trend to select values between 60° and 80°.

However, a marked trend occurs at Re ∼ 3, where fluid dynamics about the architected electrodes transition from inertial to viscous regimes, similarly concluded by Beck et al. 17 To understand how porosity influences the inertial effects, Sh vs Re plots are presented at densities ranging from 0.92 to 0.76 in FCC ( Figure 6 b) structures.

Although we expected a similar variation in our survey on the forest sector, we did not find such a marked trend, and the views on the existence of climate change and its causes were consistently similar across the studied provinces (see S3 File ).

Comparison of the statin-mediated lipidomic changes in MetS with the abnormal plasma lipidomic profile characteristic of prediabetes and T2D in the Australian Diabetes, Obesity, and Lifestyle Study and San Antonio Family Heart Study cohorts by hypergeometric analysis revealed a significant shift toward the lipid profile of controls, indicative of a marked trend toward a normolipidemic phenotype.

There is a marked trend in the widely read newspapers of publishing positive news on smartphone use by teenagers in December; but most of them published the negative effects of the device in September. 7.

There was a marked trend for the association of emotional problems and nail biting (Table 6 ).

Notably, the age of onset of stroke is continuously shifting earlier, with a marked trend toward younger populations.

Additionally, twin-bearing ewes showed a marked trend towards higher blood lactate concentrations compared to those carrying singletons. 3.1.4.

BMI is an indicator for measuring obesity, and there is a marked trend of increasing obesity in younger populations, accompanied by a rapidly rising burden.

Furthermore, there was a marked trend for PRL, E 2 , IL-1α, IL-2, IL-9, IL-10, IL-12 (p40), IL-12 (p70), IL-13, eotaxin, G-CSF, IFN-γ, KC, MCP-1, MIP-1α and RANTES to decrease on day 2 of lactation.

Early articles largely focused on counseling, but there is a marked trend toward the publication of articles on gene profile work.