“a favorable trend”

The camrelizumab group (HR: 0.218, 95% CI: 0.026–1.844, p = 0.162) showed a favorable trend, but the result was not statistically significant, likely due to small sample size and high censoring rate.

Both emulgels demonstrated a favorable trend in reducing inflammatory edema compared to the untreated control group.

Among the studies included in this systematic review, only one study failed to achieve statistical significance in adverse event reduction; however, a favorable trend with dose reduction was reported [ 18 ].

Finally, a recent meta-analysis of MSC-based therapies to treat ARDS revealed a favorable trend toward reduced mortality and inflammatory biomarkers, as well as improved pulmonary function and radiographic data.

A favorable trend was observed in increasing physical activity, and 5 themes emerged that appeared to be central to behavior change among older adults: motivation, support, tailoring, barriers, and perceptions.

Our finding showing a favorable trend of tDCS relative to sham in TMT performance warrants future studies on a larger cohort of MCI subjects.

The recent phase III BETonMACE trial, designed to investigate the impact of APA on cardiovascular outcomes in 2,425 patients with diabetes after an acute coronary syndrome, failed to meet the primary endpoint (cardiovascular death, non-fatal myocardial infarction, or stroke), but showed a favorable trend (18% difference in relative risk), indicating that APA might be a promising treatment option and suggesting that larger clinical trials are needed in this patient population.

Additionally, subgroup analysis based on clinical characteristics indicated that the addition of ICIs to the first-line treatment regimen resulted in a favorable trend of OS benefit across the majority of subgroups ( Figure S1 ).

Subgroup analysis showed a favorable trend for DVMP in high-risk patients (HR 0.78), though this did not reach statistical significance.

Conclusion Indobufen plus clopidogrel significantly reduced SUA levels and showed a favorable trend in reducing gout recurrences without compromising cardiovascular safety.

With respect to ACM, LBBAP was associated with reduced mortality (RR: 0.74), mixed CSP showed a favorable trend (RR: 0.80), and LVSP was associated with significantly increased mortality (RR: 4.00).

Nonetheless, a favorable trend has been observed in terms of the clinical outcomes of the ‘Double Kiss-Culotte’ technique in comparison to ‘classical’ Culotte techniques for both sexes.

47 In this study, the survival rate was not significantly different between the LS-MF and HS-MF groups, although there was a favorable trend in the HS-ER group compared with the HS-MF group, indicating the need for further studies with increased power.

3.3 ERA could not optimize the reproductive outcomes in EET cycles in patients with a history of previous failed embryo transfers At the beginning, some studies reported a favorable trend for the reproductive outcomes in ERA-guided EET cycles in patients with a history of previous failed embryo transfers.

Other items, including “I feel a sense of accomplishment when I successfully complete the course activities” and “In this course, I enjoy challenging materials that allow me to learn new things” also exhibited a favorable trend for the experimental group.

32 months, p = 0.10); nevertheless, there was a favorable trend in the conventional group for patients with bilobar neoplasia, portal hypertension, and elevated AFP [ 70 ].

The studies evaluated buccal gingiva levels when placing the IIP with and without CTG, obtaining a mean buccal gingiva level difference of 0.09 mm (95% CI: −0.54 to 0.72, p = 0.05), statistically not significant, but with a favorable trend.

Our study demonstrated a reduced likelihood of IC+ infarction among patients with successful reperfusion and a favorable trend with good collateral circulation.

Although a favorable trend in the mortality of liver disease due to hepatitis B was observed between 1990 and 2019 [ 51 ].

The observed reduction in serum cholesterol, although not statistically significant in this analysis ( P = .23), follows a favorable trend and is consistent with the known lipid-modifying effects of GLP-1 RAs.

The age-standardized MIR had a favorable trend over time for both sexes (from 34.3 to 22.8), and for both males (from 35.2 to 24.1) and females (from 34.5 to 21.8).

At 12 months, an improvement of initial DAS28-ESR category or maintenance in DAS28-ESR remission/LDA was shown in 181 patients (61.4%, 95% CI [55.5–66.9%]) of the main population with a favorable trend observed in switch patients compared to no-switch patients (69.2%, 95% CI [58.7–78.5%] vs. 57.8%, 95% CI [50.8–64.7%]) (Table 3 ).

Importantly, the STROKESTOP trial provided randomized evidence that systematic screening for AF in an elderly population (aged 75-76 years) with intermittent ECG monitoring was feasible and safe, and although the reduction in stroke or SE did not reach conventional statistical significance, the intervention group demonstrated a favorable trend towards improved clinical outcomes, including fewer strokes and lower mortality[ 18 ].

91 , 92 At the prespecified primary data analysis, treatment with ivonescimab/chemotherapy resulted in significant improvement in PFS (HR 0.52, 95% CI 0.41-0.66, P < 0.00001), with a favorable trend for OS (HR 0.79, 95% CI 0.62-1.01) that did not achieve statistical significance. 90 The primary analysis of OS was event driven and conducted at a time when the median follow-up for the overall population was 29.7 months, but was 9.2 months for the subgroup of patients from North America and Europ

Conversely, assessments of Subjective Task Value showed a relatively even distribution with a favorable trend, with option seven being the most frequently chosen. 4.