Regarding visual outcomes, although there was no statistically significant difference in final BCVA between the groups, the experimental group showed a favorable trend, with a higher proportion of patients experiencing vision improvement and a lower proportion with vision deterioration.
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“a favorable trend”
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In the literature
Lipid Metabolism In the pilot study of patients with MetS, TRE led to significant reduction of atherogenic lipids such as total cholesterol (~7%), low-density lipoprotein cholesterol (LDL-C) (~11%) and non-high-density lipoprotein cholesterol levels (~9%), and a favorable trend towards reduction was found for TG and LDL-C particle number [ 16 ].
In our investigation, a favorable trend in DCR was observed.
Conclusion This analysis reflects a favorable trend in recognizing the need for TVR and PVR in patients with MCT, with associated increased cost but not mortality.
Cefiderocol is well-tolerated and associated with a favorable trend toward improved overall survival [ 9 ].
Despite a favorable trend, the benefit of postoperative chemotherapy on overall survival has not been shown to be significant.
A post-hoc analysis of the data obtained from this clinical trial showed a favorable trend for patients with p53 and EGFR mutations [ 146 ].
Although there is a favorable trend, thrombopoietic agents did not significantly decrease dose delays and/or reductions compared with placebo or no treatment (21.1% [95% CI: 10.8%, 37.0%] vs 40.4% [95% CI: 9.6%, 81.2%], P = 0.364) ( Fig 2 , Table 2 ).
As a result of the very limited number of OS events, the analysis of OS was not powered enough to detect a statistical meaningful difference between these two groups but there is a favorable trend on OS towards zanubrutinib over orelabrutinib (HR 0.68).
Furthermore, a favorable trend can be observed when Hypertension is related to the patients with other coexisting diseases, since hypertensive patients demonstrated a higher number of patients with no primary End Point.
The addition of pembrolizumab was associated with a favorable trend toward improved event-free survival versus placebo plus CRT, but the difference did not reach statistical significance in the ITT population (the 24-month event-free survival rate was 63.2% for the pembrolizumab arm versus 56.2% in the placebo arm). 62 Currently, several clinical trials are exploring the role of different ICIs in LACC setting ( Table 1 ).
31 – 35 Despite these limitations, this study shows a favorable trend of the efficiency of argan oil on skin elasticity of postmenopausal women and provides a good preliminary to a larger study.
Regarding survival, a favorable trend was found for the experimental arm; however, with a median follow-up of 20.6 months, the EFS outcomes were still immature (HR 0.76; 95% CI, 0.40 to 1.44) [ 63 ]. 3.3.
Additionally, while there was a favorable trend toward a reduction in urinary albumin-to-creatinine ratio (UACR) in the ocedurenone group, this change did not reach statistical significance within the study period [ 73 ].
On the other hand, Figure 1 shows that annual cerebrovascular mortality rates in Brazilian capitals had a favorable trend to decline for all genders and age groups, despite patterns variability across the regions in the country ( Table 2 ).
Similarly, in the binary logistic regression model (dependent variable: achievement of ACR70 at week 48), the use of RTX monotherapy showed a favorable trend (adjusted OR = 1.48; 95% CI: 0.89–2.46), although not statistically significant ( p = 0.11).
The authors emphasize that there was a favorable trend in the equol producers, but this is not evident from the results or the figures.
While measuring homophily depends on the traits of the actors under consideration, a favorable trend toward homophily in scientific collaboration has been highlighted in the literature when assessed by gender.
31 From the study of differential treatment effects between younger and older patients for new cancer therapies in solid tumors, a trial evaluating treatments for breast cancer showed a favorable trend among older patients compared with young patients.
Despite the lack of statistical difference, a favorable trend toward improved exercise capacity based on the 6 MWD at 30 days and 6 months was also observed ( Figure 4 ).
Using univariate analysis, although Group 2 showed a favorable trend in patient survival rates compared with Groups 3 and 4, the statistical significance was weak.
Regarding Ann Arbor Stage, a favorable trend was observed in stages I–II: the median PFS was 92 months in Group A vs. 122 months in Group B ( p 0.074).
A recent patient-level meta-analysis has analyzed the efficacy of neoadjuvant FOLFIRINOX in BRPC, finding a favorable trend using FOLFIRINOX (median overall survival of 22 mo and median disease progression-free survival of 18.0 mo)[ 18 ].
PFS showed a favorable trend but was not statistically significant (HR=0.69, 95% CI 0.42–1.14, p=0.15).
Unpublished results ( http://10.0.82.211/rs.3.rs-2451089/v1 Peili Bu) showed that TXL led to a decrease in fibrous cap thickness increase by 27.42 μm compared with the control group, improvement in lipid core angle, reduction in severity grading of angina pectoris, and improvement in quality of life (measured by using Seattle Angina Questionnaire score), showing a favorable trend in reducing composite endpoint events (eg, all-cause death, nonfatal MI, stroke, hospitalization due to angina pectoris).