“a favorable trend”

Although the proportion of patients from the BRV group who entered into the open phase of the individual trials did not generally show a favorable trend compared to the placebo group, a meta-analysis of trials of adjunctive AEDs in adults with drug-resistant focal epilepsy found the responder rates to placebo virtually double between 1989 and 2009. 100 This may partially explain the unnoticeable difference between BRV and placebo groups.

91 , 92 At the prespecified primary data analysis, treatment with ivonescimab/chemotherapy resulted in significant improvement in PFS (HR 0.52, 95% CI 0.41-0.66, P < 0.00001), with a favorable trend for OS (HR 0.79, 95% CI 0.62-1.01) that did not achieve statistical significance. 90 The primary analysis of OS was event driven and conducted at a time when the median follow-up for the overall population was 29.7 months, but was 9.2 months for the subgroup of patients from North America and Europ

Conversely, assessments of Subjective Task Value showed a relatively even distribution with a favorable trend, with option seven being the most frequently chosen. 4.

Even cases in which preoperative head collapse had progressed by 3 mm or more, a favorable trend of necrotic lesion repair was observed ( Fig. 3 c).

4 This may suggest a favorable trend among future dental practitioners toward inclusion of tobacco cessation into practice.

Although no statistically significant overall survival benefit was observed—likely due to limited statistical power—a favorable trend in OS was noted in the combination arm, supporting its clinical relevance [ 86 ].

7 ). While in subgroup (MI vs CLW), there was a statistically significant difference with a favorable trend in the MI technique ( P = 0.00 < 0.05) (Fig. 8 ).

A recent meta-analysis of four RCTs of varicocelectomy in men with a clinically palpable varicocele, oligozoospermia and otherwise unexplained infertility a favorable trend toward surgical correction was identified. 28 This sheds some light on the controversy and reinforces the current practice by most male reproductive urologists.

For patients with high PD-L1 expression, pembrolizumab showed a favorable trend, but the pre-specified statistical difference was not reached.

Although fasting insulin did not change significantly, the 27.9% reduction in HOMA-IR in the combined group indicates a favorable trend toward enhanced insulin sensitivity, which may become significant in longer trials or larger cohorts.

The lack of significant improvement in mortality rates due to falls in the Polish elderly population observed since 2009, despite a favorable trend in the first decade of the analysis, may be related to an increase in the dynamics of growth in the trend of the oldest people (i.e., those aged over 80), particularly noticeable in the last decade (from 6.4% to 8.5%).

At the end of the 20th century, men in Poland consumed an average of 332 g of meat and its products per day, and women consumed 175 g/day, which indicates the existence of a favorable trend.

Postoperative endoscopic finding in this meta-analysis showed a favorable trend toward PPG.

Post-treatment analgesic use showed a favorable trend in the BioSi-DK group: 68.4% discontinued analgesics entirely (no analgesic use post-treatment) compared with 36.8% of controls.

Secondary Outcomes: PFS, ORR, DCR, and Serious Adverse Effects There was a favorable trend for the addition of EGFR-mAbs to the present standard chemotherapy in PFS, ORR, and DCR.

Despite a favorable trend for dyslipidemia, at the end of follow-up, about 97% of patients had levels of LDL-C ≥ 1.8102 mmol/L and over 50% did not report consumption of lipid lowering medication.

2 ) All trials showed a favorable trend toward reduced syncope recurrence in the active pacing group, with the exception of a single study.

Most of the EORTC QLQ-scales BR23 questionnaires showed a favorable trend in the quality of life except those of sexual functioning, sexual enjoyment, hair loss and the side effects of systemic therapy.

(2025) reported a slightly higher rate of excellent functional outcomes in the screw group (82.2%) compared to the K-wire group (75.3%) using Hardacre criteria, suggesting a favorable trend towards screw fixation.

Interim analysis showed a favorable trend toward OS benefit in amivantamab plus lazertinib (hazard ration (HR) 0.77; 95% CI 0.61–0.96) [ 26 ].

In bariatric surgery, the use of fibrin sealants along suture lines has been demonstrated to offer a favorable trend in reducing the incidence of postoperative complications [ 145 ].

This remarkable increase in long-term survival confirms a favorable trend of prognosis in lung cancer in Taizhou City, which was similar to the trend in other Asian countries like Japan ( 5 ) and Korea ( 14 ).

The forest plot ( Figure 3 ) displays a pooled effect estimate above 1, indicating a favorable trend toward probiotic benefit, although the lack of statistical significance and the limited number of studies warrant cautious interpretation. 3.3.

Despite a favorable trend, the Kaplan–Meier analysis indicated no significant differences in survival between the treated group vs. the shock group. 2.2.

We could not find such a favorable trend for pediatric hip disease patients, which may be explained by different ages in the populations.