“a decreasing trend”

The upward trend of blood creatinine of the rats in the DN group suggested that kidney function had changed (P<0.001), and only the PH group showed a decreasing trend (P<0.01) in ACR levels, but the intensity was lower than that in the MET group ( Figures 2B, C ). 3.5.

The average dose per prescription per month (18.27–19.21 mg before the publication of the safety letter and 15.39–16.93 mg after the publication of safety letter) followed a decreasing trend before the safety letter (TIME1: −0.02, p-value <0.01).

A decreasing trend of incidence rate was observed among patients with HIV ( P < 0.01), from 17.8 to 16.0/1,000 PY among those aged <65 years to 10.70/1,000 PY (95 % CI 6.62–16.35) in those aged 65+ years.

Although a decreasing trend was noted in the bacterial counts of many patients, it was statistically significant at 1 month only (p = 0.01, n = 10).

pylori -related PUD exhibited a decreasing trend after 2014 ( P = 0.01), drug-related PUD demonstrated an increasing trend ( P = 0.04), and idiopathic PUD showed an increasing trend in the old-age group ( P = 0.01) during 10 years.

Uptake data show a decreasing trend from (25.6 ± 5.6)% to (9.3 ± 2.9)% (p < 0.01), after 30 min exposure, and from (30.0 ± 5.6)% to (12.6 ± 3.3)% (p < 0.001), after 2 h exposure.

From December 2020 to August 2021, there was again a decreasing trend (MPC, -13.8; 95% CI: -23.3, -3.5; P = 0.01), followed by a slight increase from August 2021 to April 2022 (MPC, 4.2; 95% CI: -8.4, 18.6; P = 0.52).

Based on linear regression modeling, PFOS exposure caused a decreasing trend in total viable brood size (F(1,10)=9.22, adjusted R 2 =0.43; P = 0.01) ( Fig. 2C ). 6:2 Cl-PFESA exposure led to a similar decreasing trend in total viable brood size (F(1,10)=6.43, adjusted R 2 =0.33; P = 0.03) ( Fig. 2D ).

Conversely, the protein levels of NLRP3 were elevated in the mod group compared to the sham group ( P < 0.01) and downregulated in the Brt-L, Brt-M, and Brt-H groups in a decreasing trend compared to the mod group (Fig. 4 E, P < 0.01).

The rate of HBV infection detection from 2018 to 2021 showed a decreasing trend year by year ( P = 0.01), with the decline being most significant from 2018 to 2019 (Fig. 3 ).

In this subgroup, mean plasma indoxyl sulfate concentrations demonstrated a decreasing trend from the baseline value of 2.5 ± 0.7 μg/mL, with values of 2.1 ± 0.9 μg/mL at week 4 (p < 0.01), 2.1 ± 1.3 μg/mL at week 12 (p = 0.07), and 2.0 ± 1.1 μg/mL at week 24 (p < 0.05).

A proportion of patients with GGO and consolidation presented a decreasing trend during the 21 days after disease onset ( y = 0.48–0.09 x , p < 0.01), while a proportion of patient with all three findings including ground glass opacities, consolidation, and linear opacities presented an increasing trend ( y = 0.12–0.11 x , p < 0.01).

The longitudinal results showed a decreasing trend of negative correlation between AB and PA under T1-T3 stages (r = −0.29, r = −0.44, P < 0.01), and no significant change in the degree of negative correlation with HSK (r = −0.28, r = −0.35, P < 0.01).

During 2016–2019, already a decreasing trend in SSI incidence after colorectal surgeries was observed (7.2%; 7.2%; 6.3%; 5.0%, respectively), while the proportion of closed procedures increased ( p < 0.01, Additional file 1 : Figure S2).

The proportion of esotropia surgeries showed a decreasing trend from 2016 to 2020 (χ 2 = 31.95, P < 0.01), while the proportion of exotropia surgeries showed an increasing trend over time, but this was not significant ( P = 0.109) (Table 2 ).

There was no statistically significant difference in the proportion of boys and girls infected with adenovirus ( P = 0.176), whereas the proportion of boys with rotavirus A infection or coinfection showed a decreasing trend, accompanied by an increase in girls ( P < 0.01).

As shown in Figure 3 , the expression levels of the four candidate marker genes began to increase significantly after 0.5 h of chitin treatment ( p < 0.05), and their transcription levels reached a highly significant peak at 2–4 hpt ( p < 0.01) and then showed a decreasing trend.

SvO 2 exhibited a decreasing trend, which was more evident after the dobutamine treatment, at both T 1 and T 2 (T 1 : p = 0.01; T 2 : p = 0.04) ( Figure 6 ).

Lactoferrin could shorten time to reach full enteral feeding (weighted mean difference [WMD] = −2.11, 95% CI −3.12 to −1.10; P < .01) and showed a decreasing trend of duration of hospitalization (WMD = −1.69, 95% CI −6.87 to 3.50; P < .01; I = 95%).

Blood biochemical parameters ( Table 4 ) indicated a decreasing trend in BUN concentration with increasing levels of MP supplementation in broilers (P < 0.01).

A decreasing trend was observed for theophylline ( P = .01) (Table 1 ).

The mRNA expressions of E2F and ESR1 were positively associated with FOXM1 , significantly increasing from LPAs to SPAs (Jonckheere-Terpstra test, P<0.01 Figure 2H,I ), while FOXO3A showed a decreasing trend (Jonckheere-Terpstra test, P<0.01, Figure 2J ).

Conversely, SP-A exhibited a decreasing trend in the control and 0 h groups but increased in the serum of 24 h group ( F = 52.629, P < 0.01).

There was a decreasing trend in cesarean section rate with increasing gestational age (88.9% vs 82.9% vs 82.3%, P<0.01), while the emergency cesarean section rate increased (30.9% vs 33.9% vs 39.6%, P<0.01).

In contrast with the model group, the heart disease of rats in 3‐methyladenine and QSYQ groups reduced, and both HMI and LVMI showed a decreasing trend ( P < 0.01).