Barely Significant
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“a clear trend”

19,461 sentences · 19,461 papers · 31,348 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

There were no significant methylation differences between other tumor sub-groups (MSS/MSI-L) and normal tissue samples ( S8 Fig ) ; however, there was a clear trend of higher levels of MLH1 promoter methylation among rhesus sporadic MSI-H compared to MSS tumors as well as a notorious absence of MLH1 methylation in the only LS tumor tested, which is consistent with human CRC biology.
Therefore, while there is not a statistically significant difference in the number of total cells per gram of tissue isolated between the sequential and simultaneous digestion methods (paired t -test, p = 0.1158), there is a clear trend of more cells isolated using the sequential method (six of seven samples tested) and consistently better viability for all seven skin samples directly compared.